Search Results - "Thi Hue Kien, Duong"
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Host and viral features of human dengue cases shape the population of infected and infectious Aedes aegypti mosquitoes
Published in Proceedings of the National Academy of Sciences - PNAS (28-05-2013)“…Dengue is the most prevalent arboviral disease of humans. The host and virus variables associated with dengue virus (DENV) transmission from symptomatic dengue…”
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Genetic epidemiology of dengue viruses in phase III trials of the CYD tetravalent dengue vaccine and implications for efficacy
Published in eLife (05-09-2017)“…This study defined the genetic epidemiology of dengue viruses (DENV) in two pivotal phase III trials of the tetravalent dengue vaccine, CYD-TDV, and thereby…”
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Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti
Published in Science translational medicine (18-03-2015)“…Dengue is the most common arboviral infection of humans and is a public health burden in more than 100 countries. Aedes aegypti mosquitoes stably infected with…”
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Viral genetic diversity and protective efficacy of a tetravalent dengue vaccine in two phase 3 trials
Published in Proceedings of the National Academy of Sciences - PNAS (04-09-2018)“…Two phase 3 placebo-controlled trials of the CYD-TDV vaccine, evaluated in children aged 2–14 y (CYD14) and 9–16 y (CYD15), demonstrated vaccine efficacy (VE)…”
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A Randomized, Double-Blind Placebo Controlled Trial of Balapiravir, a Polymerase Inhibitor, in Adult Dengue Patients
Published in The Journal of infectious diseases (01-05-2013)“…Background. Dengue is the most common arboviral infection of humans. There are currently no specific treatments for dengue. Balapiravir is a prodrug of a…”
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An Evidence-Based Algorithm for Early Prognosis of Severe Dengue in the Outpatient Setting
Published in Clinical infectious diseases (01-03-2017)“…Background. Early prediction of severe dengue could significantly assist patient triage and case management. Methods. We prospectively investigated 7563…”
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Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam
Published in eLife (21-06-2024)“…Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate…”
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Epidemiological, Serological, and Virological Features of Dengue in Nha Trang City, Vietnam
Published in The American journal of tropical medicine and hygiene (01-01-2018)“…Vietnam is endemic for dengue. We conducted a series of retrospective and prospective studies to characterize the epidemiology of dengue and population…”
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The Early Whole-Blood Transcriptional Signature of Dengue Virus and Features Associated with Progression to Dengue Shock Syndrome in Vietnamese Children and Young Adults
Published in Journal of Virology (01-12-2010)“…OA Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Wolbachia wMel strain-mediated effects on dengue virus vertical transmission from Aedes aegypti to their offspring
Published in Parasites & vectors (31-08-2023)“…Dengue virus serotypes (DENV-1 to -4) can be transmitted vertically in Aedes aegpti mosquitoes. Whether infection with the wMel strain of the endosymbiont…”
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Validation of an internally controlled one-step real-time multiplex RT-PCR assay for the detection and quantitation of dengue virus RNA in plasma
Published in Journal of virological methods (01-11-2011)“…► Validation of internally controlled one step real time multiplex DENV RT-PCR assay. ► The sensitivity, specificity, linearity, reproducibility and precision…”
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Field- and clinically derived estimates of Wolbachia-mediated blocking of dengue virus transmission potential in Aedes aegypti mosquitoes
Published in Proceedings of the National Academy of Sciences - PNAS (09-01-2018)“…The wMel strain of Wolbachia can reduce the permissiveness of Aedes aegypti mosquitoes to disseminated arboviral infections. Here, we report that wMel-infected…”
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Lovastatin for the Treatment of Adult Patients With Dengue: A Randomized, Double-Blind, Placebo-Controlled Trial
Published in Clinical infectious diseases (15-02-2016)“…Background. Dengue endangers billions of people in the tropical world, yet no therapeutic is currently available. In part, the severe manifestations of dengue…”
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Higher Plasma Viremia in the Febrile Phase Is Associated With Adverse Dengue Outcomes Irrespective of Infecting Serotype or Host Immune Status: An Analysis of 5642 Vietnamese Cases
Published in Clinical infectious diseases (15-06-2021)“…Abstract Background One of the generally accepted constructs of dengue pathogenesis is that clinical disease severity is at least partially dependent upon…”
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Multiple Wolbachia strains provide comparative levels of protection against dengue virus infection in Aedes aegypti
Published in PLoS pathogens (13-04-2020)“…The insect bacterium Wolbachia pipientis is being introgressed into Aedes aegypti populations as an intervention against the transmission of medically…”
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A serotype-specific and tiled amplicon multiplex PCR method for whole genome sequencing of dengue virus
Published in Journal of virological methods (01-07-2024)“…Dengue fever, a mosquito-borne viral disease of significant public health concern in tropical and subtropical regions, is caused by any of the four serotypes…”
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Comparative Susceptibility of Aedes albopictus and Aedes aegypti to Dengue Virus Infection After Feeding on Blood of Viremic Humans: Implications for Public Health
Published in The Journal of infectious diseases (15-10-2015)“…Aedes albopictus is secondary to Aedes aegypti as a vector of dengue viruses (DENVs) in settings of endemicity, but it plays an important role in areas of…”
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Evolutionarily Successful Asian 1 Dengue Virus 2 Lineages Contain One Substitution in Envelope That Increases Sensitivity to Polyclonal Antibody Neutralization
Published in The Journal of infectious diseases (15-03-2016)“…The 4 dengue virus serotypes (DENV-1–4) cause the most prevalent mosquito-borne viral disease of humans worldwide. DENV-2 Asian 1 (A1) genotype viruses…”
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Tracking Dengue Virus Intra-host Genetic Diversity during Human-to-Mosquito Transmission
Published in PLoS neglected tropical diseases (01-09-2015)“…Dengue virus (DENV) infection of an individual human or mosquito host produces a dynamic population of closely-related sequences. This intra-host genetic…”
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Chikungunya and Zika Virus Cases Detected against a Backdrop of Endemic Dengue Transmission in Vietnam
Published in The American journal of tropical medicine and hygiene (01-07-2017)“…Between 2010 and 2014, four chikungunya and two Zika virus infections were identified among 8,105 febrile children in southern Vietnam. Zika viruses were…”
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