Search Results - "Therapeutic advances in respiratory disease"

C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis by Huang, Ian, Pranata, Raymond, Lim, Michael Anthonius, Oehadian, Amaylia, Alisjahbana, Bachti

“…Background: Patients critically ill with coronavirus disease-2019 (COVID-19) feature hyperinflammation, and the associated biomarkers may be beneficial for…”
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Defining the relationship between COPD and CVD: what are the implications for clinical practice? by Morgan, Ann D, Zakeri, Rosita, Quint, Jennifer K

“…Cardiovascular diseases (CVDs) are arguably the most important comorbidities in chronic obstructive pulmonary disease (COPD). CVDs are common in people with…”
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Lung under attack by COVID-19-induced cytokine storm: pathogenic mechanisms and therapeutic implications by Pelaia, Corrado, Tinello, Caterina, Vatrella, Alessandro, De Sarro, Giovambattista, Pelaia, Girolamo

“…The lung is a key target of the cytokine storm that can be triggered by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for the…”
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Targeting the gut–lung microbiota axis by means of a high-fibre diet and probiotics may have anti-inflammatory effects in COVID-19 infection by Conte, Luana, Toraldo, Domenico Maurizio

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 1 is a 2019 novel coronavirus, which only in the European area has led to more than 300,000 cases…”
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Doxycycline treatment of high-risk COVID-19-positive patients with comorbid pulmonary disease by Yates, Paul A., Newman, Steven A., Oshry, Lauren J., Glassman, Robert H., Leone, Ashton M., Reichel, Elias

“…Infection with novel SARS-CoV-2 carries significant morbidity and mortality in patients with pulmonary compromise, such as lung cancer, autoimmune disease, and…”
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The role of viral infections in exacerbations of chronic obstructive pulmonary disease and asthma by Hewitt, Richard, Farne, Hugo, Ritchie, Andrew, Luke, Emma, Johnston, Sebastian L., Mallia, Patrick

“…Asthma and chronic obstructive pulmonary disease (COPD) are major causes of global morbidity and mortality worldwide. The clinical course of both asthma and…”
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Role of immune-checkpoint inhibitors in lung cancer by Jain, Prantesh, Jain, Chhavi, Velcheti, Vamsidhar

“…Immune checkpoint inhibitors, mainly drugs targeting the programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) and cytotoxic T-lymphocyte…”
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Omalizumab, the first available antibody for biological treatment of severe asthma: more than a decade of real-life effectiveness by Pelaia, Corrado, Calabrese, Cecilia, Terracciano, Rosa, de Blasio, Francesco, Vatrella, Alessandro, Pelaia, Girolamo

“…Omalizumab was the first, and for a long time the only available monoclonal antibody for the add-on treatment of severe allergic asthma. In particular,…”
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Management of advanced non-small cell lung cancers with known mutations or rearrangements: latest evidence and treatment approaches by Shea, Meghan, Costa, Daniel B., Rangachari, Deepa

“…Precision oncology is now the evidence-based standard of care for the management of many advanced non-small cell lung cancers (NSCLCs). Expert consensus has…”
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Respiratory viral infections in the elderly by Watson, Alastair, Wilkinson, Tom M. A.

“…With the global over 60-year-old population predicted to more than double over the next 35 years, caring for this aging population has become a major global…”
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Digital healthcare in COPD management: a narrative review on the advantages, pitfalls, and need for further research by Watson, Alastair, Wilkinson, Tom M.A.

“…Chronic obstructive pulmonary disease (COPD) remains a leading cause of morbidity and mortality despite current treatment strategies which focus on smoking…”
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Validation of a visual analog scale for assessing cough severity in patients with chronic cough by Martin Nguyen, Allison, Bacci, Elizabeth D., Vernon, Margaret, Birring, Surinder S., Rosa, Carmen La, Muccino, David, Schelfhout, Jonathan

“…Introduction: Patients with chronic cough experience considerable burden. The cough severity visual analog scale (VAS) records patients’ assessment of cough…”
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Early COPD: current evidence for diagnosis and management by Fazleen, Aishath, Wilkinson, Tom

“…Chronic obstructive pulmonary disease (COPD) affects one-tenth of the world’s population and has been identified as a major global unmet health need by the…”
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Mepolizumab improves sino-nasal symptoms and asthma control in severe eosinophilic asthma patients with chronic rhinosinusitis and nasal polyps: a 12-month real-life study by Detoraki, Aikaterini, Tremante, Eugenio, D’Amato, Maria, Calabrese, Cecilia, Casella, Claudia, Maniscalco, Mauro, Poto, Remo, Brancaccio, Raffaele, Boccia, Matilde, Martino, Maria, Imperatore, Clara, Spadaro, Giuseppe

“…Background: Severe eosinophilic asthma is frequently associated to chronic rhinosinusitis and nasal polyposis (CRSwNP) that contribute to poor asthma control…”
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Risk of pneumonitis in cancer patients treated with immune checkpoint inhibitors: a meta-analysis by Abdel-Rahman, Omar, Fouad, Mona

“…Background: A meta-analysis of the risk of pneumonitis associated with the use of immune checkpoint inhibitors in cancer patients has been conducted. Methods:…”
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Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation by Goërtz, Yvonne M. J., Spruit, Martijn A., Van ‘t Hul, Alex J., Peters, Jeannette B., Van Herck, Maarten, Nakken, Nienke, Djamin, Remco S., Burtin, Chris, Thong, Melissa S. Y., Coors, Arnold, Meertens-Kerris, Yvonne, Wouters, Emiel F. M., Prins, Judith B., Franssen, Frits M. E., Muris, Jean W. M., Vanfleteren, Lowie E. G. W., Sprangers, Mirjam A. G., Janssen, Daisy J. A., Vercoulen, Jan H.

“…Background: The objective of this study was to compare fatigue levels between subjects with and without COPD, and to investigate the relationship between…”
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Impact of elexacaftor/tezacaftor/ivacaftor on depression and anxiety in cystic fibrosis by Zhang, Lijia, Albon, Dana, Jones, Marieke, Bruschwein, Heather

“…Background: Cystic fibrosis (CF) is associated with worsening of depression and anxiety symptoms. Elexacaftor/tezacaftor/ivacaftor (Trikafta®), a cystic…”
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Biomarkers in the diagnosis of pleural diseases: a 2018 update by Porcel, José M.

“…The use of biomarkers on pleural fluid (PF) specimens may assist the decision-making process and enhance clinical diagnostic pathways. Three paradigmatic…”
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Leicester Cough Questionnaire validation and clinically important thresholds for change in refractory or unexplained chronic cough by Nguyen, Allison Martin, Schelfhout, Jonathan, Muccino, David, Bacci, Elizabeth D., La Rosa, Carmen, Vernon, Margaret, Birring, Surinder S.

“…Introduction: The Leicester Cough Questionnaire (LCQ), a cough-specific quality-of-life measure, evaluates the impact of cough across physical, psychological,…”
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The role of the NLRP3 inflammasome in pulmonary diseases by Hosseinian, Nima, Cho, Young, Lockey, Richard F, Kolliputi, Narasaiah

“…Respiratory diseases and lung injuries are one of the leading causes of death in the world. One critical component of these diseases is exaggerated…”
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