Search Results - "Theodossiou, Sophia K"

Engineering Cell-ECM-Material Interactions for Musculoskeletal Regeneration by Jones, Calvin L, Penney, Brian T, Theodossiou, Sophia K

“…The extracellular microenvironment regulates many of the mechanical and biochemical cues that direct musculoskeletal development and are involved in…”
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Dielectrophoretic Characterization of Tenogenically Differentiating Mesenchymal Stem Cells by Giduthuri, Anthony T, Theodossiou, Sophia K, Schiele, Nathan R, Srivastava, Soumya K

“…Tendons are collagenous musculoskeletal tissues that connect muscles to bones and transfer the forces necessary for movement. Tendons are susceptible to injury…”
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A 3D printed mechanical bioreactor for investigating mechanobiology and soft tissue mechanics by Raveling, Abigail R., Theodossiou, Sophia K., Schiele, Nathan R.

“…[Display omitted] Mechanical loading is an important cue for directing stem cell fate and engineered tissue formation in vitro. Stem cells cultured on…”
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Akt signaling is activated by TGFβ2 and impacts tenogenic induction of mesenchymal stem cells by Theodossiou, Sophia K, Murray, Jett B, Hold, LeeAnn A, Courtright, Jeff M, Carper, Anne M, Schiele, Nathan R

“…Tissue engineered and regenerative approaches for treating tendon injuries are challenged by the limited information on the cellular signaling pathways driving…”
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Ex-vivo quantification of ovine pia arachnoid complex biomechanical properties under uniaxial tension by Conley Natividad, Gabryel, Theodossiou, Sophia K, Schiele, Nathan R, Murdoch, Gordon K, Tsamis, Alkiviadis, Tanner, Bertrand, Potirniche, Gabriel, Mortazavi, Martin, Vorp, David A, Martin, Bryn A

“…The pia arachnoid complex (PAC) is a cerebrospinal fluid-filled tissue conglomerate that surrounds the brain and spinal cord. Pia mater adheres directly to the…”
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Models of tendon development and injury by Theodossiou, Sophia K, Schiele, Nathan R

“…Tendons link muscle to bone and transfer forces necessary for normal movement. Tendon injuries can be debilitating and their intrinsic healing potential is…”
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TGFβ2-induced tenogenesis impacts cadherin and connexin cell-cell junction proteins in mesenchymal stem cells by Theodossiou, Sophia K., Tokle, John, Schiele, Nathan R.

“…Tenogenic differentiation of stem cells is needed for tendon tissue engineering approaches. A current challenge is the limited information on the…”
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Localized, on-demand, sustained drug delivery from biopolymer-based materials by Wu, Junqi, Shaidani, Sawnaz, Theodossiou, Sophia K, Hartzell, Emily J, Kaplan, David L

“…Local drug delivery facilitiates higher concentrations of drug molecules at or near the treatment site to enhance treatment efficiency and reduce drug toxicity…”
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Perspectives on scaling production of adipose tissue for food applications by Yuen Jr, John S.K., Stout, Andrew J., Kawecki, N. Stephanie, Letcher, Sophia M., Theodossiou, Sophia K., Cohen, Julian M., Barrick, Brigid M., Saad, Michael K., Rubio, Natalie R., Pietropinto, Jaymie A., DiCindio, Hailey, Zhang, Sabrina W., Rowat, Amy C., Kaplan, David L.

“…With rising global demand for food proteins and significant environmental impact associated with conventional animal agriculture, it is important to develop…”
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Onset of neonatal locomotor behavior and the mechanical development of Achilles and tail tendons by Theodossiou, Sophia K., Bozeman, Aimee L., Burgett, Nicholas, Brumley, Michele R., Swann, Hillary E., Raveling, Abigail R., Becker, Jordan J., Schiele, Nathan R.

“…Tendon tissue engineering approaches are challenged by a limited understanding of the role mechanical loading plays in normal tendon development. We propose…”
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Neonatal Spinal Cord Transection Decreases Hindlimb Weight-Bearing and Affects Formation of Achilles and Tail Tendons by Theodossiou, Sophia K, Pancheri, Nicholas M, Martes, Alleyna C, Bozeman, Aimee L, Brumley, Michele R, Raveling, Abigail R, Courtright, Jeffrey M, Schiele, Nathan R

“…Mechanical loading may be required for proper tendon formation. However, it is not well understood how tendon formation is impacted by the development of…”
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Sudan Black B Pretreatment to Suppress Autofluorescence in Silk Fibroin Scaffolds by Foster, Olivia, Shaidani, Sawnaz, Theodossiou, Sophia K., Falcucci, Thomas, Hiscox, Derek, Smiley, Brooke M., Romano, Chiara, Kaplan, David L.

“…Natural polymers are extensively utilized as scaffold materials in tissue engineering and 3D disease modeling due to their general features of…”
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Cell-cell junctions in developing and adult tendons by Theodossiou, Sophia K., Murray, Jett B., Schiele, Nathan R.

“…Tendons connect muscles to bones to transfer the forces necessary for movement. Cell-cell junction proteins, cadherins and connexins, may play a role in tendon…”
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Dielectrophoresis as a tool for electrophysiological characterization of stem cells by Giduthuri, Anthony T, Theodossiou, Sophia K, Schiele, Nathan R, Srivastava, Soumya K

“…Dielectrophoresis (DEP), a nonlinear electrokinetic technique caused by Maxwell-Wagner interfacial polarization of neutral particles in an electrolyte…”
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Akt signaling is activated by TGF[beta]2 and impacts tenogenic induction of mesenchymal stem cells by Theodossiou, Sophia K, Murray, Jett B, Hold, LeeAnn A, Courtright, Jeff M, Carper, Anne M, Schiele, Nathan R

“…Background Tissue engineered and regenerative approaches for treating tendon injuries are challenged by the limited information on the cellular signaling…”
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Mechanical and Cellular Factors Regulating Tendon Development by Theodossiou, Sophia K

“…Tendons are collagenous musculoskeletal tissues that transfer forces from muscle to bone to facilitate movement. Tendons are frequently injured, and the…”
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