Search Results - "Theodosiou, Anastasia A"
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Qualitative interview study exploring the perspectives of pregnant women on participating in controlled human infection research in the UK
Published in BMJ open (27-12-2023)“…IntroductionPregnant women have been historically excluded from interventional research. While recent efforts have been made to improve their involvement,…”
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Controlled human infection with Neisseria lactamica in late pregnancy to measure horizontal transmission and microbiome changes in mother–neonate pairs: a single-arm interventional pilot study protocol
Published in BMJ open (18-05-2022)“…IntroductionInfant upper respiratory microbiota are derived partly from the maternal respiratory tract, and certain microbiota are associated with altered risk…”
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Artificial intelligence, machine learning and deep learning: Potential resources for the infection clinician
Published in The Journal of infection (01-10-2023)“…Artificial intelligence (AI), machine learning and deep learning (including generative AI) are increasingly being investigated in the context of research and…”
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Excluding Clinically Significant Bacteremia by 24 Hours in Otherwise Well Febrile Children Younger Than 16 Years: A Study of More Than 50,000 Blood Cultures
Published in The Pediatric infectious disease journal (01-09-2019)“…BACKGROUND:In febrile children given empiric parenteral antibiotics, guidelines advise provisional reporting of negative blood cultures and antibiotic review…”
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Microbiotoxicity: antibiotic usage and its unintended harm to the microbiome
Published in Current opinion in infectious diseases (01-10-2023)“…Antibiotic use is associated with development of antimicrobial resistance and dysregulation of the microbiome (the overall host microbial community). These…”
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A systematic review and meta‐analysis of the prevalence of human cytomegalovirus shedding in seropositive pregnant women
Published in Reviews in medical virology (01-11-2022)“…The detection of human cytomegalovirus (HCMV) in an individual's bodily fluid by culture techniques or through HCMV DNA detection by polymerase chain reaction,…”
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A Questionnaire-based Study Exploring Participant Perspectives in a Perinatal Human Challenge Trial
Published in The Pediatric infectious disease journal (01-11-2023)“…Pregnant women have historically been excluded from most medical research, including human challenge studies. The proof-of-concept Lactamica 9 human challenge…”
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The nonpathogenic commensal Neisseria: friends and foes in infectious disease
Published in Current opinion in infectious diseases (01-10-2019)“…PURPOSE OF REVIEWNonpathogenic commensal Neisseria are rarely considered in the clinical setting despite evidence that they can cause invasive opportunistic…”
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The infant pharyngeal microbiomes: origin, impact and manipulation
Published in Current opinion in infectious diseases (01-12-2020)“…PURPOSE OF REVIEWThere has been an exponential increase in research into infant microbiome evolution, and it appears that pharyngeal microbiota are associated…”
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Manipulating the infant respiratory microbiomes to improve clinical outcomes: A review of the literature
Published in The Journal of infection (01-06-2021)“…•Infant respiratory microbiome profiles are associated with disease (including respiratory tract infections and asthma), although the mechanism for this…”
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Cassandra’s prophecy: medic or mother? Exploring the relevance of age-related fertility decline to women in medicine
Published in Reproductive biomedicine online (01-07-2013)“…Abstract This commentary presents a response to ‘Cassandra’s prophecy’ from the perspective of a final-year medical student, in an attempt to gauge the…”
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Abortion legislation: exploring perspectives of general practitioners and obstetrics and gynaecology clinicians
Published in Reproductive biomedicine online (01-02-2015)“…Abstract Abortion legislation remains a contentious topic in the UK, which receives much attention from politicians, clinicians and professional bodies alike…”
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The politics of human embryo research and the motivation to achieve PGD
Published in Reproductive biomedicine online (01-05-2011)“…Abstract This article reports a historical study of factors influencing the achievement of clinical preimplantation genetic diagnosis (PGD) in 1990, 22 years…”
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Effect of colonisation with Neisseria lactamica on cross-reactive anti-meningococcal B-cell responses: a randomised, controlled, human infection trial
Published in The Lancet. Microbe (01-12-2022)“…Pharyngeal colonisation by the commensal bacterium Neisseria lactamica inhibits colonisation by Neisseria meningitidis and has an inverse epidemiological…”
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Controlled human infection with Neisseria lactamica induces B-cell responses that are cross-reactive with Neisseria meningitidis
Published in The Journal of immunology (1950) (01-05-2020)“…Neisseria lactamica (Nlac) is a commensal of the human oropharynx. Colonisation with Nlac significantly reduces colonisation by N. meningitidis (Nmen). We…”
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