Search Results - "Theodore, William"

Generic antiepileptic drugs—Safe or harmful in patients with epilepsy? by Holtkamp, Martin, Theodore, William H.

“…Summary Generic antiepileptic drugs (AED) are significantly cheaper than brand name drugs, and may reduce overall health care expenditures. Regulatory bodies…”
Get full text

Epilepsy in the Hippocratic collection: Seizures and syndromes by Theodore, William H.

“…•The Hippocratic collection presents a physiologic view of epilepsy.•It appears to distinguish between seizures occurring alone, or associated with another…”
Get full text

Recommendations for the use of structural magnetic resonance imaging in the care of patients with epilepsy: A consensus report from the International League Against Epilepsy Neuroimaging Task Force by Bernasconi, Andrea, Cendes, Fernando, Theodore, William H., Gill, Ravnoor S., Koepp, Matthias J., Hogan, Robert Edward, Jackson, Graeme D., Federico, Paolo, Labate, Angelo, Vaudano, Anna Elisabetta, Blümcke, Ingmar, Ryvlin, Philippe, Bernasconi, Neda

“…Structural magnetic resonance imaging (MRI) is of fundamental importance to the diagnosis and treatment of epilepsy, particularly when surgery is being…”
Get full text

Presurgical Focus Localization in Epilepsy: PET and SPECT by Theodore, William H., MD

“…Positron emission tomography (PET) and single photon emission computed tomography (SPECT) can be used to assist localization of seizure foci in patients with…”
Get full text

Circadian and circaseptan rhythms in human epilepsy: a retrospective cohort study by Karoly, Philippa J, Goldenholz, Daniel M, Freestone, Dean R, Moss, Robert E, Grayden, David B, Theodore, William H, Cook, Mark J

“…Epilepsy has long been suspected to be governed by cyclic rhythms, with seizure rates rising and falling periodically over weeks, months, or even years. The…”
Get full text

Infection with HHV-6 and its role in epilepsy by Bartolini, Luca, Theodore, William H., Jacobson, Steven, Gaillard, William D.

“…•This review examines the role of HHV-6 infection in epilepsy.•HHV-6 infection has been linked with febrile seizures, TLE and encephalitis.•We discuss…”
Get full text

Practice guideline summary: Use of fMRI in the presurgical evaluation of patients with epilepsy by Szaflarski, Jerzy P, Gloss, David, Binder, Jeffrey R, Gaillard, William D, Golby, Alexandra J, Holland, Scott K, Ojemann, Jeffrey, Spencer, David C, Swanson, Sara J, French, Jacqueline A, Theodore, William H

“…Objective: To assess the diagnostic accuracy and prognostic value of functional MRI (fMRI) in determining lateralization and predicting postsurgical language…”
Get full text

The Relationship between Glucose Metabolism, Resting-State fMRI BOLD Signal, and GABA A -Binding Potential: A Preliminary Study in Healthy Subjects and Those with Temporal Lobe Epilepsy by Nugent, Allison C, Martinez, Ashley, D'Alfonso, Alana, Zarate, Carlos A, Theodore, William H

“…Glucose metabolism has been associated with magnitude of blood oxygen level-dependent (BOLD) signal and connectivity across subjects within the default mode…”
Get full text

Practice guideline summary: Use of fMRI in the presurgical evaluation of patients with epilepsy: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology by Szaflarski, Jerzy P, Gloss, David, Binder, Jeffrey R, Gaillard, William D, Golby, Alexandra J, Holland, Scott K, Ojemann, Jeffrey, Spencer, David C, Swanson, Sara J, French, Jacqueline A, Theodore, William H

“…OBJECTIVE:To assess the diagnostic accuracy and prognostic value of functional MRI (fMRI) in determining lateralization and predicting postsurgical language…”
Get full text

Neuroinflammation in neocortical epilepsy measured by PET imaging of translocator protein by Dickstein, Leah P., Liow, Jeih‐San, Austermuehle, Alison, Zoghbi, Sami, Inati, Sara K., Zaghloul, Kareem, Zanotti‐Fregonara, Paolo, Theodore, William H.

“…Objectives Neuroinflammation, implicated in epilepsy, can be imaged in humans with positron emission tomography (PET) ligands for translocator protein 18 kDa…”
Get full text

Identification of clinically relevant biomarkers of epileptogenesis — a strategic roadmap by Simonato, Michele, Agoston, Denes V., Brooks-Kayal, Amy, Dulla, Chris, Fureman, Brandy, Henshall, David C., Pitkänen, Asla, Theodore, William H., Twyman, Roy E., Kobeissy, Firas H., Wang, Kevin K., Whittemore, Vicky, Wilcox, Karen S.

“…Onset of many forms of epilepsy occurs after an initial epileptogenic insult or as a result of an identified genetic defect. Given that the precipitating…”
Get full text

Confusing placebo effect with natural history in epilepsy: A big data approach by Goldenholz, Daniel M., Moss, Robert, Scott, Jonathan, Auh, Sungyoung, Theodore, William H.

“…For unknown reasons, placebos reduce seizures in clinical trials in many patients. It is also unclear why some drugs showing statistical superiority to placebo…”
Get full text

Neuroinflammation in Temporal Lobe Epilepsy Measured Using Positron Emission Tomographic Imaging of Translocator Protein by Gershen, Leah D, Zanotti-Fregonara, Paolo, Dustin, Irene H, Liow, Jeih-San, Hirvonen, Jussi, Kreisl, William C, Jenko, Kimberly J, Inati, Sara K, Fujita, Masahiro, Morse, Cheryl L, Brouwer, Chad, Hong, Jinsoo S, Pike, Victor W, Zoghbi, Sami S, Innis, Robert B, Theodore, William H

“…Neuroinflammation may play a role in epilepsy. Translocator protein 18 kDa (TSPO), a biomarker of neuroinflammation, is overexpressed on activated microglia…”
Get more information

Characterization of atypical language activation patterns in focal epilepsy by Berl, Madison M., Zimmaro, Lauren A., Khan, Omar I., Dustin, Irene, Ritzl, Eva, Duke, Elizabeth S., Sepeta, Leigh N., Sato, Susumu, Theodore, William H., Gaillard, William D.

“…Objective Functional magnetic resonance imaging is sensitive to the variation in language network patterns. Large populations are needed to rigorously assess…”
Get full text

Sleep physiology in patients with epilepsy: Influence of seizures on rapid eye movement (REM) latency and REM duration by Kilgore‐Gomez, Alexandrea, Norato, Gina, Theodore, William H., Inati, Sara K., Rahman, Shareena A.

“…Objective A well‐established bidirectional relationship exists between sleep and epilepsy. Patients with epilepsy tend to have less efficient sleep and shorter…”
Get full text

Language functional MRI and direct cortical stimulation in epilepsy preoperative planning by Austermuehle, Alison, Cocjin, John, Reynolds, Richard, Agrawal, Shubhi, Sepeta, Leigh, Gaillard, William D., Zaghloul, Kareem A., Inati, Sara, Theodore, William H.

“…Objective Presurgical language assessment can help minimize damage to eloquent cortex during resective epilepsy surgery. Two methods for presurgical language…”
Get full text

Immune‐mediated epilepsies by Granata, Tiziana, Cross, Helen, Theodore, William, Avanzini, Giuliano

“…Summary A pathogenic role of immunity in epilepsies has long been suggested based on observations of the efficacy of immune‐modulating treatments and, more…”
Get full text

Long‐term monitoring of cardiorespiratory patterns in drug‐resistant epilepsy by Goldenholz, Daniel M., Kuhn, Amanda, Austermuehle, Alison, Bachler, Martin, Mayer, Christopher, Wassertheurer, Siegfried, Inati, Sara K., Theodore, William H.

“…Summary Objective Sudden unexplained death in epilepsy (SUDEP) during inpatient electroencephalography (EEG) monitoring has been a rare but potentially…”
Get full text

Language lateralization from task‐based and resting state functional MRI in patients with epilepsy by Rolinski, Rachel, You, Xiaozhen, Gonzalez‐Castillo, Javier, Norato, Gina, Reynolds, Richard C., Inati, Sara K., Theodore, William H.

“…We compared resting state (RS) functional connectivity and task‐based fMRI to lateralize language dominance in 30 epilepsy patients (mean age = 33; SD = 11; 12…”
Get full text

Neuroinflammation imaging markers for epileptogenesis by Koepp, Matthias J., Årstad, Eric, Bankstahl, Jens P., Dedeurwaerdere, Stefanie, Friedman, Alon, Potschka, Heidrun, Ravizza, Teresa, Theodore, William H., Baram, Tallie Z.

“…Summary Epilepsy can be a devastating disorder. In addition to debilitating seizures, epilepsy can cause cognitive and emotional problems with reduced quality…”
Get full text