Search Results - "Theiss, Arianne L"

Gut bacteria signaling to mitochondria in intestinal inflammation and cancer by Jackson, Dakota N., Theiss, Arianne L.

“…The gastrointestinal microbiome plays a pivotal role in physiological homeostasis of the intestine as well as in the pathophysiology of diseases including…”
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Essential turmeric oils enhance anti-inflammatory efficacy of curcumin in dextran sulfate sodium-induced colitis by Toden, Shusuke, Theiss, Arianne L., Wang, Xuan, Goel, Ajay

“…Turmeric has been used as a medicinal herb for thousands of years for treatment of various disorders. Although curcumin is the most studied active constituents…”
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The role and therapeutic potential of prohibitin in disease by Theiss, Arianne L., Sitaraman, Shanthi V.

“…Prohibitin 1 (PHB1), a pleiotropic protein in the cell, has been implicated in the regulation of proliferation, apoptosis, transcription, mitochondrial protein…”
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Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis by Jackson, Dakota N, Panopoulos, Marina, Neumann, William L, Turner, Kevin, Cantarel, Brandi L, Thompson-Snipes, LuAnn, Dassopoulos, Themistocles, Feagins, Linda A, Souza, Rhonda F, Mills, Jason C, Blumberg, Richard S, Venuprasad, K, Thompson, Winston E, Theiss, Arianne L

“…Although perturbations in mitochondrial function and structure have been described in the intestinal epithelium of Crohn's disease and ulcerative colitis…”
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Autophagy in Crohn's Disease: Converging on Dysfunctional Innate Immunity by Alula, Kibrom M, Theiss, Arianne L

“…Crohn's disease (CD) is a chronic inflammatory bowel disease marked by relapsing, transmural intestinal inflammation driven by innate and adaptive immune…”
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Inner mitochondrial membrane protein Prohibitin 1 mediates Nix-induced, Parkin-independent mitophagy by Alula, Kibrom M., Delgado-Deida, Yaritza, Callahan, Rosemary, Till, Andreas, Underwood, Lucia, Thompson, Winston E., Souza, Rhonda F., Dassopoulos, Themistocles, Onyiah, Joseph, Venuprasad, K., Theiss, Arianne L.

“…Autophagy of damaged mitochondria, called mitophagy, is an important organelle quality control process involved in the pathogenesis of inflammation, cancer,…”
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Prohibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells by Kathiria, Arwa S, Butcher, Lindsay D, Feagins, Linda A, Souza, Rhonda F, Boland, C Richard, Theiss, Arianne L

“…Autophagy is an adaptive response to extracellular and intracellular stress by which cytoplasmic components and organelles, including damaged mitochondria, are…”
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Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice by Alula, Kibrom M, Dowdell, Alexander S, LeBere, Brittany, Lee, J Scott, Levens, Cassandra L, Kuhn, Kristine A, Kaipparettu, Benny A, Thompson, Winston E, Blumberg, Richard S, Colgan, Sean P, Theiss, Arianne L

“…Intestinal epithelial cell (IEC) mitochondrial dysfunction involvement in inflammatory bowel diseases (IBD), including Crohn's disease affecting the small…”
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Physiological Reports celebrates its first 10 years by Adams, Josephine C., Price, Oliver J., Rogers, Natasha, Rounds, Sharon, Taruno, Akiyuki, Theiss, Arianne L., Uchida, Shizuka, Wright, David C.

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RORγt protein modifications and IL-17-mediated inflammation by Kumar, Ritesh, Theiss, Arianne L., Venuprasad, K.

“…RORγt, the master transcription factor for cytokine interleukin (IL)-17, is expressed explicitly in Th17 cells, γδT cells, and type 3 innate lymphoid cells in…”
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Prohibitin protects against oxidative stress in intestinal epithelial cells by Theiss, Arianne L, Idell, Richard D, Srinivasan, Shanthi, Klapproth, Jan-Michael, Jones, Dean P, Merlin, Didier, Sitaraman, Shanthi V

“…Prohibitin (PHB) is an evolutionarily conserved and ubiquitously expressed protein whose expression or function in intestinal diseases is not known. In this…”
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Mitochondria and Inflammatory Bowel Diseases: Toward a Stratified Therapeutic Intervention by Ho, Gwo-tzer, Theiss, Arianne L

“…Mitochondria serve numerous critical cellular functions, rapidly responding to extracellular stimuli and cellular demands while dynamically communicating with…”
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Targeting Mitochondrial Damage as a Therapeutic for Ileal Crohn’s Disease by Alula, Kibrom M., Jackson, Dakota N., Smith, Andrew D., Kim, Daniel S., Turner, Kevin, Odstrcil, Elizabeth, Kaipparettu, Benny A., Dassopoulos, Themistocles, Venuprasad, K., Feagins, Linda A., Theiss, Arianne L.

“…Paneth cell defects in Crohn’s disease (CD) patients (called the Type I phenotype) are associated with worse clinical outcomes. Recent studies have implicated…”
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Nanoparticle‐based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis by Theiss, Arianne L., Laroui, Hamed, Obertone, Tracy S., Chowdhury, Indrajit, Thompson, Winston E., Merlin, Didier, Sitaraman, Shanthi V.

“…Background: Intestinal epithelial expression of antioxidants and nuclear factor kappa B (NF‐κB) contribute to mucosal barrier integrity and epithelial…”
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NLRP6 in host defense and intestinal inflammation by Venuprasad, K., Theiss, Arianne L.

“…NLRP6 is a member of the NLR (nucleotide-oligomerization domain-like receptor) family of proteins that recognize pathogen-derived factors and damage-associated…”
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Burn the fat: colon cancer tumors are skilled at lipid storage during obesity by Theiss, Arianne L., Williams, Christopher S.

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Ptpn2: A Critical Regulator of Paneth Cell Homeostasis by Theiss, Arianne L.

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Mitochondrial function and gastrointestinal diseases by Haque, Parsa S., Kapur, Neeraj, Barrett, Terrence A., Theiss, Arianne L.

“…Mitochondria are dynamic organelles that function in cellular energy metabolism, intracellular and extracellular signalling, cellular fate and stress…”
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Stat3: friend or foe in colitis and colitis-associated cancer? by Han, Jie, Theiss, Arianne L

“…Chronic inflammation predisposes tissue to cancer development. Individuals afflicted with inflammatory bowel diseases are at an increased risk of developing…”
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Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation by Mukherjee, Sandip, Kumar, Ritesh, Tsakem Lenou, Elviche, Basrur, Venkatesha, Kontoyiannis, Dimitris L., Ioakeimidis, Fotis, Mosialos, George, Theiss, Arianne L., Flavell, Richard A., Venuprasad, K.

“…The inflammasome NLRP6 plays a crucial role in regulating inflammation and host defense against microorganisms in the intestine. However, the molecular…”
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