Search Results - "Theisen, Terence C"
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Transcriptional signatures of clonally derived Toxoplasma tachyzoites reveal novel insights into the expression of a family of surface proteins
Published in PloS one (25-02-2022)“…Toxoplasma gondii has numerous, large, paralogous gene families that are likely critical for supporting its unparalleled host range: nearly any nucleated cell…”
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Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii
Published in PLoS pathogens (22-01-2018)“…Toxoplasma gondii is an obligate intracellular parasite that can infect virtually all nucleated cells in warm-blooded animals. The ability of Toxoplasma…”
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A single-parasite transcriptional atlas of Toxoplasma Gondii reveals novel control of antigen expression
Published in eLife (17-02-2020)“…a protozoan parasite, undergoes a complex and poorly understood developmental process that is critical for establishing a chronic infection in its intermediate…”
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Coimmunoprecipitation with MYR1 Identifies Three Additional Proteins within the Toxoplasma gondii Parasitophorous Vacuole Required for Translocation of Dense Granule Effectors into Host Cells
Published in mSphere (19-02-2020)“…is a ubiquitous, intracellular protozoan that extensively modifies infected host cells through secreted effector proteins. Many such effectors must be…”
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Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells
Published in Journal of virology (01-08-2015)“…Ebola virus (EBOV) causes a severe hemorrhagic fever with a deficient immune response, lymphopenia, and lymphocyte apoptosis. Dendritic cells (DC), which…”
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Patterns of Interferon Regulatory Factor 1 (IRF1) Expression By Respiratory Epithelial Cells Reveal Non-Redundancy of Type I Versus Type III Interferons
Published in Journal of allergy and clinical immunology (01-02-2016)“…Whether types I and III IFN have non-redundant functions in anti-viral defense is unknown. Because transcription factors dictate cellular phenotype and…”
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IFN-beta and IFN-lambda1 Induce Kinetically Distinct Patterns of Transcription Factor Interferon Stimulated Genes in Respiratory Epithelial Cells
Published in Journal of allergy and clinical immunology (01-02-2015)“…Methods We determined unique or cooperative roles for types I and III IFN in cellular activation by stimulating BEAS-2B human respiratory epithelial cells with…”
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Distinct Patterns of Expression of Transcription Factors in Response to Interferonβ and Interferonλ1
Published in Journal of interferon & cytokine research (01-10-2016)“…After viral infection, type I and III interferons (IFNs) are coexpressed by respiratory epithelial cells (RECs) and activate the ISGF3 transcription factor…”
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210: Characterization of human interferon subtype and interferon-stimulated gene signatures
Published in Cytokine (Philadelphia, Pa.) (01-09-2013)“…Type I interferons (IFNs) are expressed by all nucleated cells in response to viral pathogens and modulate innate and adaptive immune responses by stimulating…”
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High-throughput quantitative real-time RT-PCR assay for determining expression profiles of types I and III interferon subtypes
Published in Journal of visualized experiments (24-03-2015)“…Described in this report is a qRT-PCR assay for the analysis of seventeen human IFN subtypes in a 384-well plate format that incorporates highly specific…”
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Transcriptional signatures of clonally derived Toxoplasma tachyzoites reveal novel insights into the expression of a family of surface proteins
Published in PloS one (01-01-2022)“…Toxoplasma gondii has numerous, large, paralogous gene families that are likely critical for supporting its unparalleled host range: nearly any nucleated cell…”
Get full text
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High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
Published in Journal of visualized experiments (24-03-2015)Get full text
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