Search Results - "Theill, Lars E."

RANK-L AND RANK: T Cells, Bone Loss, and Mammalian Evolution by Theill, Lars E, Boyle, William J, Penninger, Josef M

“…TNF and TNFR family proteins play important roles in the control of cell death, proliferation, autoimmunity, the function of immune cells, or the organogenesis…”
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Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms by Hevroni, D, Rattner, A, Bundman, M, Lederfein, D, Gabarah, A, Mangelus, M, Silverman, M A, Kedar, H, Naor, C, Kornuc, M, Hanoch, T, Seger, R, Theill, L E, Nedivi, E, Richter-Levin, G, Citri, Y

“…Long-term plasticity of the central nervous system (CNS) involves induction of a set of genes whose identity is incompletely characterized. To identify…”
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Function of the Homeodomain Protein GHF1 in Pituitary Cell Proliferation by Castrillo, José-Luis, Theill, Lars E., Karin, Michael

“…Mutations that cause pituitary dwarfism in the mouse reside in the gene encoding the transcription factor growth hormone factor 1 (GHF1 or pit1). These dwarf…”
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Dissection of functional domains of the pituitary-specific transcription factor GHF-1 by Theill, Lars E, Castrillo, José-Luis, Wu, David, Karin, Michael

“…The specific expression of growth hormone (GH) in the somatotrophic cells of the anterior pituitary is largely attributable to a short promoter in the 5'…”
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Isoform-specific expression and function of neuregulin by Meyer, D, Yamaai, T, Garratt, A, Riethmacher-Sonnenberg, E, Kane, D, Theill, L E, Birchmeier, C

“…Neuregulin (also known as NDF, heregulin, ARIA, GGF or SMDF), induces cell growth and differentiation. Biological effects of neuregulin are mediated by members…”
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TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation by Xia, X Z, Treanor, J, Senaldi, G, Khare, S D, Boone, T, Kelley, M, Theill, L E, Colombero, A, Solovyev, I, Lee, F, McCabe, S, Elliott, R, Miner, K, Hawkins, N, Guo, J, Stolina, M, Yu, G, Wang, J, Delaney, J, Meng, S Y, Boyle, W J, Hsu, H

“…We and others recently reported tumor necrosis factor (TNF) and apoptosis ligand-related leukocyte-expressed ligand 1 (TALL-1) as a novel member of the TNF…”
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Neuritin: A Gene Induced by Neural Activity and Neurotrophins that Promotes Neuritogenesis by Naeve, Gregory S., Ramakrishnan, Meena, Kramer, Rainer, Hevroni, Dana, Citri, Yoav, Theill, Lars E.

“…Neural activity and neurotrophins induce synaptic remodeling in part by altering gene expression. A cDNA encoding a glycosylphoshatidylinositol-anchored…”
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Maintenance of Acetylcholine Receptor Number by Neuregulins at the Neuromuscular Junction in Vivo by Sandrock, Alfred W., Dryer, Stuart E., Rosen, Kenneth M., Gozani, Shai N., Kramer, Rainer, Theill, Lars E., Fischbach, Gerald D.

“…ARIA (for acetylcholine receptor-inducing activity), a protein purified on the basis of its ability to stimulate acetylcholine receptor (AChR) synthesis in…”
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APRIL and TALL-1 and receptors BCMA and TACI: system for regulating humoral immunity by Theill, Lars E, Yu, Gang, Boone, Tom, Delaney, John, Hawkins, Nessa, Kelley, Michael, Ramakrishnan, Meena, McCabe, Susan, Qiu, Wan-rong, Kornuc, Masayo, Xia, Xing-Zhong, Guo, Jane, Stolina, Marina, Boyle, William J, Sarosi, Ildiko, Hsu, Hailing, Senaldi, Giorgio

“…We report that the tumor neurosis factor homolog APRIL (a proliferation-inducing ligand) stimulates in vitro proliferation of primary B and T cells and…”
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A Set of Genes Expressed in Response to Light in the Adult Cerebral Cortex and Regulated during Development by Nedivi, Elly, Fieldust, Sheila, Theill, Lars E., Hevroni, Dana

“…Activity-dependent plasticity is thought to underlie both formation of appropriate synaptic connections during development and reorganization of adult cortical…”
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The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein by Bodner, M, Castrillo, J L, Theill, L E, Deerinck, T, Ellisman, M, Karin, M

“…Growth hormone factor 1 (GHF-1) is a pituitary-specific transcription factor that plays a critical role in cell type-specific expression of the growth hormone…”
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Regulation of the pituitary-specific homeobox gene GHF1 by cell-autonomous and environmental cues by McCormick, Alison, Brady, Helen, Theill, Lars E, Karin, Michael

“…Homeodomain proteins function in determination of mating type in yeast, segmentation in fruit flies and cell-type specific gene expression in mammals. In…”
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Polyethylene Glycolated Recombinant TNF Receptor I Improves Insulitis and Reduces Incidence of Spontaneous and Cyclophosphamide-Accelerated Diabetes in Nonobese Diabetic Mice by Wang, Jin-Lin, Qian, Xueming, Chinookoswong, Narumol, Lu, John, Chow, Gwyneth, Theill, Lars E, Shi, Zhi-Qing

“…We have conducted three studies to examine the role of TNFα in islet destruction in female nonobese diabetic mouse (NOD) mice, a model of human autoimmune…”
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An Activation Function in Pit-1 Required Selectively for Synergistic Transcription by Chang, W, Zhou, W, Theill, L E, Baxter, J D, Schaufele, F

“…Synergistic transcription activation is a key component in the generation of the spectrum of eukaryotic promoter activities by a limited number of…”
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Neuregulins with an Ig-Like Domain are Essential for Mouse Myocardial and Neuronal Development by Kramer, Rainer, Bucay, Nathan, Kane, Darci J., Martin, Laura E., Tarpley, John E., Theill, Lars E.

“…Neuregulins are ligands for the erbB family of receptor tyrosine kinases and mediate growth and differentiation of neural crest, muscle, breast cancer, and…”
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Expression of GHF-1 protein in mouse pituitaries correlates both temporally and spatially with the onset of growth hormone gene activity by Dollé, P, Castrillo, J L, Theill, L E, Deerinck, T, Ellisman, M, Karin, M

“…The relationship between expression of the pituitary-specific transcription factor, GHF-1, and activation of the growth hormone and prolactin genes during…”
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GHF-1-promoter-targeted immortalization of a somatotropic progenitor cell results in dwarfism in transgenic mice by LEW, D, BRADY, H, KLAUSING, K, YAGINUMA, K, THEILL, L. E, STAUBER, C, KARIN, M, MELLON, P. L

“…During pituitary development, the homeo domain protein GHF-1 is required for generation of somatotropes and lactotropes and for growth hormone (GH) and…”
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Differential splicing of the GHF1 primary transcript gives rise to two functionally distinct homeodomain proteins by Theill, L.E., Hattori, K., Lazzaro, D., Castrillo, J.L., Karin, M.

“…The POU domain protein GHF‐1 has a critical role in generation, proliferation and phenotypic expression of three pituitary cell types. GHF‐1 functions in part…”
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Growth hormone gene regulation: a paradigm for cell-type-specific gene activation by Karin, M, Castrillo, J L, Theill, L E

“…The growth hormone (GH) gene is specifically expressed within specialized cells of the anterior pituitary. The central role in GH gene activation is played by…”
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Partial processing of the neuropeptide Y precursor in transfected CHO cells by Wulff, Birgitte Schjellerup, O'Hare, Mairead M.T., Boel, Esper, Theill, Lars E., Schwartz, Thue W.

“…The activation of regulatory peptides by post-translational modification of their biosynthetic precursors is generally thought to occur only in neuroendocrine…”
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