Search Results - "The journal of peptide research"

Effects of single d-amino acid substitutions on disruption of β-sheet structure and hydrophobicity in cyclic 14-residue antimicrobial peptide analogs related to gramicidin S by Lee, D.L., Powers, J.P.S., Pflegerl, K., Vasil, M.L., Hancock, R.E.W, Hodges, R.S.

“…:  Gramicidin S (GS) is a 10‐residue cyclic β‐sheet peptide with lytic activity against the membranes of both microbial and human cells, i.e. it possesses…”
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Chemoselective synthesis of peptides containing major advanced glycation end-products of lysine and arginine by Gruber, P., Hofmann, T.

“…:  Useful methodologies have been developed, enabling the straightforward synthesis of peptides containing Nɛ‐(carboxymethyl)‐l‐lysine (CML) and…”
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Purification and characterization of charantin, a napin-like ribosome-inactivating peptide from bitter gourd (Momordica charantia) seeds by Parkash, A., Ng, T.B., Tso, W.W.

“…:  A peptide designated charantin, with a molecular mass of 9.7 kDa, was isolated from bitter gourd seeds. The procedure comprised affinity chromatography on…”
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Development and validation of opioid ligand-receptor interaction models: The structural basis of mu vs. delta selectivity by Mosberg, H.I., Fowler, C.B.

“…: Opioid receptor binding conformations for two structurally related, conformationally constrained tetrapeptides, JOM‐6 (µ receptor selective) and JOM‐13 (δ…”
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Purification and mass spectroscopic analysis of human CB1 cannabinoid receptor functionally expressed using the baculovirus system by Xu, W., Filppula, S.A., Mercier, R., Yaddanapudi, S., Pavlopoulos, S., Cai, J., Pierce, W.M., Makriyannis, A.

“…:  The cannabinoid receptor 1 (CB1) cannabinoid receptor is an essential component of the cannabinergic system. It has been recognized as a therapeutic target…”
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Roles of residues 3 and 4 in cyclic tetrapeptide ligand recognition by the κ-opioid receptor by Przydzial, M.J., Pogozheva, I.D., Bosse, K.E., Andrews, S.M., Tharp, T.A., Traynor, J.R., Mosberg, H.I.

“…:  A series of cyclic, disulfide‐ or dithioether‐containing tetrapeptides based on previously reported potent μ‐ and δ‐selective analogs has been explored with…”
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From pro defensins to defensins: synthesis and characterization of human neutrophil pro α-defensin-1 and its mature domain by Wu, Z., Prahl, A., Powell, R., Ericksen, B., Lubkowski, J., Lu, W.

“…: Human neutrophil α‐defensins (HNPs) are small, cationic, Cys‐rich antimicrobial proteins that play important roles in innate immunity against infectious…”
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Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity by Yoshida, K., Mukai, Y., Niidome, T., Takashi, C., Tokunaga, Y., Hatakeyama, T., Aoyagi, H.

“…: A 25‐mer cationic peptide pleurocidin, isolated from the winter flounder, has broad antibacterial activity. To clarify the structure–activity relationship,…”
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Structure-based design, synthesis, and pharmacologic evaluation tf peptide RGS4 inhibitors by Jin, Y., Zhong, H., Omnaas, J.R., Neubig, R.R., Mosberg, H.I.

“…:  Regulators of G‐protein signaling (RGS) proteins form a multifunctional signaling family. A key role of RGS proteins is binding to the G‐protein Gα‐subunit…”
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Synthesis and AT2 receptor-binding properties of angiotensin II analogues by Rosenström, U., Sköld, C., Lindeberg, G., Botros, M., Nyberg, F., Hallberg, A., Karlén, A.

“…:  The present study investigates the importance of the amino acid side chains in the octapeptide angiotensin II (Ang II) for binding to the AT2 receptor. A…”
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Measurement of the affinity of melittin for zwitterionic and anionic membranes using immobilized lipid biosensors by Lee, T.-H., Mozsolits, H., Aguilar, M.-I.

“…: The binding of melittin to zwitterionic dimyristyphosphatidylcholine (DMPC) and anionic dimyristylphosphatidylglycerol (DMPG) was analysed using two…”
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Design of high affinity cyclic pentapeptide ligands for κ-opioid receptors by Przydzial, M.J., Pogozheva, I.D., Ho, J.C., Bosse, K.E., Sawyer, E., Traynor, J.R., Mosberg, H.I.

“…:  Using results from our previously reported cyclic opioid peptide series and reliable models for μ‐, δ‐, and κ‐opioid receptors (MOR, DOR, and KOR,…”
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Comparative gene transfer efficiency of low molecular weight polylysine DNA-condensing peptides by McKenzie, Donald L., Collard, Wendy T., Rice, Kevin G.

“…: In a previous report (M.S. Wadhwa et al. (1997) Bioconjugate Chem.8, 81–88), we synthesized a panel of polylysine‐containing peptides and determined that a…”
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Biological activities of cecropin B-thanatin hybrid peptides by Hongbiao, W., Baolong, N., Lihua, H., Weifeng, S., Zhiqi, M.

“…:  Ten kinds of hybrid peptides containing the N‐terminal residues of cecropin B (CB) and C‐terminal of thanatin (TH) were constructed and expressed as…”
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Regulators of G protein signaling (RGS proteins): Novel central nervous system drug targets by Neubig, R. R.

“…: Many drugs of abuse signal through receptors that couple to G proteins (GPCRs), so the factors that control GPCR signaling are likely to be important to the…”
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Stability and specificity of heterodimer formation for the coiled-coil neck regions of the motor proteins Kif3A and Kif3B: the role of unstructured oppositely charged regions by Chana, M.S., Tripet, B.P., Mant, C.T., Hodges, R.

“…:  We investigated the folding, stability, and specificity of dimerization of the neck regions of the kinesin‐like proteins Kif3A (residues 356–416) and Kif3B…”
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Conformation and interaction of the cyclic cationic antimicrobial peptides in lipid bilayers by Jelokhani-Niaraki, M., Prenner, E.J., Kay, C.M., McElhaney, R.N., Hodges, R.S.

“…: To investigate the role of peptide–membrane interactions in the biological activity of cyclic cationic peptides, the conformations and interactions of four…”
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Structure-activity relationships of arodyn, a novel acetylated kappa opioid receptor antagonist by Bennett, M.A., Murray, T.F., Aldrich, J.V.

“…:  We previously reported that the novel dynorphin A (Dyn A, Tyr‐Gly‐Gly‐Phe‐Leu‐Arg‐Arg‐Ile‐Arg‐Pro‐Lys‐Leu‐Lys‐Trp‐Asp‐Asn‐Gln) analog arodyn…”
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Increased antibacterial activity of 15-residue murine lactoferricin derivatives by Strøm, M.B., Stensen, W., Svendsen, J.S., Rekdal, Ø.

“…: LFM W8 is a synthetic 15‐residue lactoferricin derivative (H2N‐EKCLRWQWEMRKVGG‐COOH), corresponding to residues 16–30 of the mature murine lactoferrin…”
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Binding of agonists, antagonists and inverse agonists to the human δ-opioid receptor produces distinctly different conformational states distinguishable by plasmon-waveguide resonance spectroscopy by Salamon, Z., Hruby, V. J., Tollin, G., Cowell, S.

“…: Structural changes induced by the binding of agonists, antagonists and inverse agonists to the cloned δ‐opioid receptor from human brain immobilized in a…”
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