Search Results - "The Swiss HIV Cohort Study"

Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial by Sculier, Delphine, Wandeler, Gilles, Yerly, Sabine, Marinosci, Annalisa, Stoeckle, Marcel, Bernasconi, Enos, Braun, Dominique L, Vernazza, Pietro, Cavassini, Matthias, Buzzi, Marta, Metzner, Karin J, Decosterd, Laurent A, Günthard, Huldrych F, Schmid, Patrick, Limacher, Andreas, Egger, Matthias, Calmy, Alexandra

“…Dolutegravir (DTG)-based dual therapy is becoming a new paradigm for both the initiation and maintenance of HIV treatment. The SIMPL'HIV study investigated the…”
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Diagnosis of latent tuberculosis infection is associated with reduced HIV viral load and lower risk for opportunistic infections in people living with HIV by Kusejko, Katharina, Günthard, Huldrych F, Olson, Gregory S, Zens, Kyra, Darling, Katharine, Khanna, Nina, Furrer, Hansjakob, Vetter, Pauline, Bernasconi, Enos, Vernazza, Pietro, Hoffmann, Matthias, Kouyos, Roger D, Nemeth, Johannes

“…Approximately 28% of the human population have been exposed to Mycobacterium tuberculosis (MTB), with the overwhelming majority of infected individuals not…”
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Assessing the drivers of syphilis among men who have sex with men in Switzerland reveals a key impact of screening frequency: A modelling study by Balakrishna, Suraj, Salazar-Vizcaya, Luisa, Schmidt, Axel J, Kachalov, Viacheslav, Kusejko, Katharina, Thurnheer, Maria Christine, Roth, Jan A, Nicca, Dunja, Cavassini, Matthias, Battegay, Manuel, Schmid, Patrick, Bernasconi, Enos, Günthard, Huldrych F, Rauch, Andri, Kouyos, Roger D

“…Over the last decade, syphilis diagnoses among men-who-have-sex-with-men (MSM) have strongly increased in Europe. Understanding the drivers of the ongoing…”
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A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna by Speich, Benjamin, Chammartin, Frédérique, Smith, Daniel, Stoeckle, Marcel P, Amico, Patrizia, Eichenberger, Anna L, Hasse, Barbara, Schuurmans, Macé M, Müller, Thomas, Tamm, Michael, Dickenmann, Michael, Abela, Irene A, Trkola, Alexandra, Hirsch, Hans H, Manuel, Oriol, Cavassini, Matthias, Hemkens, Lars G, Briel, Matthias, Mueller, Nicolas J, Rauch, Andri, Günthard, Huldrych F, Koller, Michael T, Bucher, Heiner C, Kusejko, Katharina

“…Late 2019, a new highly contagious coronavirus SARS-CoV-2 has emerged in Wuhan, China, causing within 2 months a pandemic with the highest disease burden in…”
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Effect of Mutation and Genetic Background on Drug Resistance in Mycobacterium tuberculosis by FENNER, Lukas, EGGER, Matthias, SIEGRIST, Hans H, FURRER, Hansjakob, CALMY, Alexandra, FEHR, Jan, STALDER, Jesica Mazza, NINET, Beatrice, BÖTTGER, Erik C, GAGNEUX, Sebastien, BODMER, Thomas, ALTPETER, Ekkehardt, ZWAHLEN, Marcel, JATON, Katia, PFYFFER, Gaby E, BORRELL, Sonia, DUBUIS, Olivier, BRUDERER, Thomas

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Migrating a Well-Established Longitudinal Cohort Database From Oracle SQL to Research Electronic Data Entry (REDCap): Data Management Research and Design Study by Kusejko, Katharina, Smith, Daniel, Scherrer, Alexandra, Paioni, Paolo, Kohns Vasconcelos, Malte, Aebi-Popp, Karoline, Kouyos, Roger D, Günthard, Huldrych F, Kahlert, Christian R

“…Providing user-friendly electronic data collection tools for large multicenter studies is key for obtaining high-quality research data. Research Electronic…”
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HIV Viral Load Response to Antiretroviral Therapy According to the Baseline CD4 Cell Count and Viral Load by Phillips, Andrew N, Staszewski, Schlomo, Weber, Rainer, Kirk, Ole, Francioli, Patrick, Miller, Veronica, Vernazza, Pietro, Lundgren, Jens D, Ledergerber, Bruno, for the Swiss HIV Cohort Study, the Frankfurt HIV Clinic Cohort, and the EuroSIDA Study Group

“…CONTEXT It is unclear whether delay in initiation of antiretroviral therapy (ART) may lead to a poorer viral load response for patients with human…”
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Cost-effectiveness of genotypic antiretroviral resistance testing in HIV-infected patients with treatment failure by Sendi, Pedram, Günthard, Huldrych F, Simcock, Mathew, Ledergerber, Bruno, Schüpbach, Jörg, Battegay, Manuel

“…Genotypic antiretroviral resistance testing (GRT) in HIV infection with drug resistant virus is recommended to optimize antiretroviral therapy, in particular…”
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CD161 Defines a Functionally Distinct Subset of Pro-Inflammatory Natural Killer Cells by Kurioka, Ayako, Cosgrove, Cormac, Simoni, Yannick, van Wilgenburg, Bonnie, Geremia, Alessandra, Björkander, Sophia, Sverremark-Ekström, Eva, Thurnheer, Christine, Günthard, Huldrych F, Khanna, Nina, Walker, Lucy Jane, Arancibia-Cárcamo, Carolina V, Newell, Evan W, Willberg, Christian B, Klenerman, Paul

“…CD161 is a C-type lectin-like receptor expressed on the majority of natural killer (NK) cells; however, the significance of CD161 expression on NK cells has…”
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HIV rebounds from latently infected cells, rather than from continuing low-level replication by Joos, Beda, Fischer, Marek, Kuster, Herbert, Pillai, Satish K, Wong, Joseph K, Böni, Jürg, Hirschel, Bernard, Weber, Rainer, Trkola, Alexandra, Günthard, Huldrych F

“…Rapid rebound of plasma viremia in patients after interruption of long-term combination antiretroviral therapy (cART) suggests persistence of low-level…”
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Unsupervised machine learning predicts future sexual behaviour and sexually transmitted infections among HIV-positive men who have sex with men by Andresen, Sara, Balakrishna, Suraj, Mugglin, Catrina, Schmidt, Axel J, Braun, Dominique L, Marzel, Alex, Doco Lecompte, Thanh, Darling, Katharine EA, Roth, Jan A, Schmid, Patrick, Bernasconi, Enos, Günthard, Huldrych F, Rauch, Andri, Kouyos, Roger D, Salazar-Vizcaya, Luisa

“…Machine learning is increasingly introduced into medical fields, yet there is limited evidence for its benefit over more commonly used statistical methods in…”
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Characteristics, Determinants, and Clinical Relevance of CD4 T Cell Recovery to <500 Cells/μL in HIV Type 1-Infected Individuals Receiving Potent Antiretroviral Therapy by Gilbert R. Kaufmann, Hansjakob Furrer, Bruno Ledergerber, Perrin, Luc, Milos Opravil, Pietro Vernazza, Matthias Cavassini, Bernasconi, Enos, Martin Rickenbach, Hirschel, Bernard, Battegay, Manuel, The Swiss HIV Cohort Study

“…Background. The CD4 T cell count recovery in human immunodeficiency virus type 1 (HIV-1)-infected individuals receiving potent antiretroviral therapy (ART)…”
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Correcting for Population Stratification Reduces False Positive and False Negative Results in Joint Analyses of Host and Pathogen Genomes by Naret, Olivier, Chaturvedi, Nimisha, Bartha, Istvan, Hammer, Christian, Fellay, Jacques

“…Studies of host genetic determinants of pathogen sequence variations can identify sites of genomic conflicts, by highlighting variants that are implicated in…”
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Factors Associated with the Incidence of Type 2 Diabetes Mellitus in HIV-Infected Participants in the Swiss HIV Cohort Study by Ledergerber, Bruno, Furrer, Hansjakob, Rickenbach, Martin, Lehmann, Roger, Elzi, Luigia, Hirschel, Bernard, Cavassini, Matthias, Bernasconi, Enos, Schmid, Patrick, Egger, Matthias, Weber, Rainer

“…Background. Human immunodeficiency virus (HIV)–infected persons may be at increased risk for developing type 2 diabetes mellitus because of viral coinfection…”
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Adherence as a predictor of the development of class-specific resistance mutations: the Swiss HIV Cohort Study by von Wyl, Viktor, Klimkait, Thomas, Yerly, Sabine, Nicca, Dunja, Furrer, Hansjakob, Cavassini, Matthias, Calmy, Alexandra, Bernasconi, Enos, Böni, Jürg, Aubert, Vincent, Günthard, Huldrych F, Bucher, Heiner C, Glass, Tracy R

“…Non-adherence is one of the strongest predictors of therapeutic failure in HIV-positive patients. Virologic failure with subsequent emergence of resistance…”
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Real-Life Therapeutic Concentration Monitoring of Long-Acting Cabotegravir and Rilpivirine: Preliminary Results of an Ongoing Prospective Observational Study in Switzerland by Thoueille, Paul, Alves Saldanha, Susana, Schaller, Fabian, Munting, Aline, Cavassini, Matthias, Braun, Dominique, Günthard, Huldrych F, Kusejko, Katharina, Surial, Bernard, Furrer, Hansjakob, Rauch, Andri, Ustero, Pilar, Calmy, Alexandra, Stoeckle, Marcel, Battegay, Manuel, Marzolini, Catia, Andre, Pascal, Guidi, Monia, Buclin, Thierry, Decosterd, Laurent A

“…SHCS#879 is an ongoing Switzerland-wide multicenter observational study conducted within the Swiss HIV Cohort Study (SHCS) for the prospective follow-up of…”
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Assessment of Overlap of Phylogenetic Transmission Clusters and Communities in Simple Sexual Contact Networks: Applications to HIV-1 by Villandre, Luc, Stephens, David A, Labbe, Aurelie, Günthard, Huldrych F, Kouyos, Roger, Stadler, Tanja

“…Transmission patterns of sexually-transmitted infections (STIs) could relate to the structure of the underlying sexual contact network, whose features are…”
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An Approach to Quantifying the Interaction between Behavioral and Transmission Clusters by Salazar-Vizcaya, Luisa, Kusejko, Katharina, Günthard, Huldrych F, Böni, Jürg, Metzner, Karin J, Braun, Dominique L, Nicca, Dunja, Bernasconi, Enos, Calmy, Alexandra, Darling, Katharine E A, Wandeler, Gilles, Kouyos, Roger D, Rauch, Andri, The Swiss Hiv Cohort Study

“…We hypothesize that patterns of sexual behavior play a role in the conformation of transmission networks, i.e., the way you behave might influence whom you…”
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Parent-offspring regression to estimate the heritability of an HIV-1 trait in a realistic setup by Bachmann, Nadine, Turk, Teja, Kadelka, Claus, Marzel, Alex, Shilaih, Mohaned, Böni, Jürg, Aubert, Vincent, Klimkait, Thomas, Leventhal, Gabriel E, Günthard, Huldrych F, Kouyos, Roger

“…Parent-offspring (PO) regression is a central tool to determine the heritability of phenotypic traits; i.e., the relative extent to which those traits are…”
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Detecting Selection in the HIV-1 Genome during Sexual Transmission Events by Seifert, David, Joos, Beda, Braun, Dominique L, Oberle, Corinna S, Schenkel, Corinne D, Kuster, Herbert, Grube, Christina, Böni, Jürg, Yerly, Sabine, Aubert, Vincent, Klimkait, Thomas, Günthard, Huldrych F, Beerenwinkel, Niko, Metzner, Karin J, On Behalf Of The Swiss Hiv Cohort Study

“…Little is known about whether and how variation in the HIV-1 genome affects its transmissibility. Assessing which genomic features of HIV-1 are under positive…”
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