Search Results - "The Lancet infectious diseases"

Estimates of the severity of coronavirus disease 2019: a model-based analysis by Verity, Robert, Okell, Lucy C, Dorigatti, Ilaria, Winskill, Peter, Whittaker, Charles, Imai, Natsuko, Cuomo-Dannenburg, Gina, Thompson, Hayley, Walker, Patrick G T, Fu, Han, Dighe, Amy, Griffin, Jamie T, Baguelin, Marc, Bhatia, Sangeeta, Boonyasiri, Adhiratha, Cori, Anne, Cucunubá, Zulma, FitzJohn, Rich, Gaythorpe, Katy, Green, Will, Hamlet, Arran, Hinsley, Wes, Laydon, Daniel, Nedjati-Gilani, Gemma, Riley, Steven, van Elsland, Sabine, Volz, Erik, Wang, Haowei, Wang, Yuanrong, Xi, Xiaoyue, Donnelly, Christl A, Ghani, Azra C, Ferguson, Neil M

“…In the face of rapidly changing data, a range of case fatality ratio estimates for coronavirus disease 2019 (COVID-19) have been produced that differ…”
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Early dynamics of transmission and control of COVID-19: a mathematical modelling study by Kucharski, Adam J, Russell, Timothy W, Diamond, Charlie, Liu, Yang, Edmunds, John, Funk, Sebastian, Eggo, Rosalind M, Sun, Fiona, Jit, Mark, Munday, James D, Davies, Nicholas, Gimma, Amy, van Zandvoort, Kevin, Gibbs, Hamish, Hellewell, Joel, Jarvis, Christopher I, Clifford, Sam, Quilty, Billy J, Bosse, Nikos I, Abbott, Sam, Klepac, Petra, Flasche, Stefan

“…An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to 95 333 confirmed cases as of March 5, 2020. Understanding the early…”
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Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial by Zhang, Yanjun, Zeng, Gang, Pan, Hongxing, Li, Changgui, Hu, Yaling, Chu, Kai, Han, Weixiao, Chen, Zhen, Tang, Rong, Yin, Weidong, Chen, Xin, Hu, Yuansheng, Liu, Xiaoyong, Jiang, Congbing, Li, Jingxin, Yang, Minnan, Song, Yan, Wang, Xiangxi, Gao, Qiang, Zhu, Fengcai

“…With the unprecedented morbidity and mortality associated with the COVID-19 pandemic, a vaccine against COVID-19 is urgently needed. We investigated CoronaVac…”
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Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study by Bi, Qifang, Wu, Yongsheng, Mei, Shujiang, Ye, Chenfei, Zou, Xuan, Zhang, Zhen, Liu, Xiaojian, Wei, Lan, Truelove, Shaun A, Zhang, Tong, Gao, Wei, Cheng, Cong, Tang, Xiujuan, Wu, Xiaoliang, Wu, Yu, Sun, Binbin, Huang, Suli, Sun, Yu, Zhang, Juncen, Ma, Ting, Lessler, Justin, Feng, Tiejian

“…Rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, prompted heightened surveillance in Shenzhen, China. The…”
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Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study by Aliabadi, Shirin, Lopez-Bernal, Jamie, Moore, Nathan, Golubchik, Tanya, Cogger, Benjamin, Wantoch, Michelle, Spellman, Karla, McCluggage, Kathryn, Munn, Robert, Fuller, William, Charalampous, Themoula, Robson, Samuel, Abudahab, Khalil, Willingham, Iona, Raviprakash, Veena, Loose, Matthew, Coll, Francesc, Wilson, Harry, Pybus, Oliver, Zarebski, Alex, Jahun, Aminu, Fisher, Chloe, Siveroni, Igor, Boyd, Olivia, Smollett, Katherine, Poplawski, Radoslaw, Sluga, Graciela, Nichols, Jenna, Johnson, Natasha, Singer, Joshua, Nickbakhsh, Seema, Carden, Holli, Taha, Yusri, Blacow, Rachel, McHugh, Martin, Stanley, Rachael, Meader, Emma, Coupland, Lindsay, Peto, Timothy, Sloan, Tim, Chauhan, Anoop, Pearson, Clare, Robinson, Esther, Muir, Peter, Pymont, Hannah, Hutchings, Stephanie, Bibby, David, Lee, David, Ellaby, Nicholas, Manesis, Nikos, Bishop, Chloe, Gaskin, Amy, Gatica-Wilcox, Bree, Cronin, Michelle, Cottrell, Simon, Edwards, Sue, Aydin, Alp, Ratcliffe, Liz, Acheson, Erwan, Ellard, Sian, Irish-Tavares, Dianne, Hart, Jennifer, Symmonds, Amanda, Bourgeois, Yann, Dent, Hannah, Paul, Hannah, Partridge, David, Bonner, Stephen, Silveira, Siona, Williams, Charlotte, Jeremiah, Sarah, Berry, Lisa, Jones, Katie, Percival, Benita, Hesketh, Andrew, Girgis, Sophia, Forrest, Sally, Gupta, Ravi, Ludden, Catherine, Bewshea, Claire, Temperton, Ben, Warwick-Dugdale, Joanna, Studholme, David, Jeffries, Aaron, Jackson, Kathryn, Gregory, Richard, Wierzbicki, Claudia, Green, Luke, Freeman, Timothy, Cerda, Alberto, Alderton, Alex, Amato, Roberto, Ariani, Cristina, Beale, Mathew, Bellis, Katherine, Kwiatkowski, Dominic, McGuigan, Samantha, Prestwood, Liam, Spencer Chapman, Michael, Tonkin-Hill, Gerry

“…The SARS-CoV-2 delta (B.1.617.2) variant was first detected in England in March, 2021. It has since rapidly become the predominant lineage, owing to high…”
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Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study by Menni, Cristina, Klaser, Kerstin, May, Anna, Polidori, Lorenzo, Capdevila, Joan, Louca, Panayiotis, Sudre, Carole H, Nguyen, Long H, Drew, David A, Merino, Jordi, Hu, Christina, Selvachandran, Somesh, Antonelli, Michela, Murray, Benjamin, Canas, Liane S, Molteni, Erika, Graham, Mark S, Modat, Marc, Joshi, Amit D, Mangino, Massimo, Hammers, Alexander, Goodman, Anna L, Chan, Andrew T, Wolf, Jonathan, Steves, Claire J, Valdes, Ana M, Ourselin, Sebastien, Spector, Tim D

“…The Pfizer-BioNTech (BNT162b2) and the Oxford-AstraZeneca (ChAdOx1 nCoV-19) COVID-19 vaccines have shown excellent safety and efficacy in phase 3 trials. We…”
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Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial by Xia, Shengli, Zhang, Yuntao, Wang, Yanxia, Wang, Hui, Yang, Yunkai, Gao, George Fu, Tan, Wenjie, Wu, Guizhen, Xu, Miao, Lou, Zhiyong, Huang, Weijin, Xu, Wenbo, Huang, Baoying, Wang, Huijuan, Wang, Wei, Zhang, Wei, Li, Na, Xie, Zhiqiang, Ding, Ling, You, Wangyang, Zhao, Yuxiu, Yang, Xuqin, Liu, Yang, Wang, Qian, Huang, Lili, Yang, Yongli, Xu, Guangxue, Luo, Bojian, Wang, Wenling, Liu, Peipei, Guo, Wanshen, Yang, Xiaoming

“…The ongoing COVID-19 pandemic warrants accelerated efforts to test vaccine candidates. We aimed to assess the safety and immunogenicity of an inactivated…”
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Viral dynamics in mild and severe cases of COVID-19 by Liu, Yang, Yan, Li-Meng, Wan, Lagen, Xiang, Tian-Xin, Le, Aiping, Liu, Jia-Ming, Peiris, Malik, Poon, Leo L M, Zhang, Wei

“…Patients who had any of the following features at the time of, or after, admission were classified as severe cases: (1) respiratory distress (≥30 breaths per…”
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Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study by Singanayagam, Anika, Hakki, Seran, Dunning, Jake, Madon, Kieran J, Crone, Michael A, Koycheva, Aleksandra, Derqui-Fernandez, Nieves, Barnett, Jack L, Whitfield, Michael G, Varro, Robert, Charlett, Andre, Kundu, Rhia, Fenn, Joe, Cutajar, Jessica, Quinn, Valerie, Conibear, Emily, Barclay, Wendy, Freemont, Paul S, Taylor, Graham P, Ahmad, Shazaad, Zambon, Maria, Ferguson, Neil M, Lalvani, Ajit, Badhan, Anjna, Dustan, Simon, Tejpal, Chitra, Ketkar, Anjeli V, Narean, Janakan Sam, Hammett, Sarah, McDermott, Eimear, Pillay, Timesh, Houston, Hamish, Luca, Constanta, Samuel, Jada, Bremang, Samuel, Evetts, Samuel, Poh, John, Anderson, Charlotte, Jackson, David, Miah, Shahjahan, Ellis, Joanna, Lackenby, Angie

“…The SARS-CoV-2 delta (B.1.617.2) variant is highly transmissible and spreading globally, including in populations with high vaccination rates. We aimed to…”
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Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study by Antonelli, Michela, Penfold, Rose S, Merino, Jordi, Sudre, Carole H, Molteni, Erika, Berry, Sarah, Canas, Liane S, Graham, Mark S, Klaser, Kerstin, Modat, Marc, Murray, Benjamin, Kerfoot, Eric, Chen, Liyuan, Deng, Jie, Österdahl, Marc F, Cheetham, Nathan J, Drew, David A, Nguyen, Long H, Pujol, Joan Capdevila, Hu, Christina, Selvachandran, Somesh, Polidori, Lorenzo, May, Anna, Wolf, Jonathan, Chan, Andrew T, Hammers, Alexander, Duncan, Emma L, Spector, Tim D, Ourselin, Sebastien, Steves, Claire J

“…COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness in real-world data, but some people still become infected with SARS-CoV-2 after…”
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Real estimates of mortality following COVID-19 infection by Baud, David, Qi, Xiaolong, Nielsen-Saines, Karin, Musso, Didier, Pomar, Léo, Favre, Guillaume

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Clinical and virological data of the first cases of COVID-19 in Europe: a case series by Lescure, Francois-Xavier, Bouadma, Lila, Nguyen, Duc, Parisey, Marion, Wicky, Paul-Henri, Behillil, Sylvie, Gaymard, Alexandre, Bouscambert-Duchamp, Maude, Donati, Flora, Le Hingrat, Quentin, Enouf, Vincent, Houhou-Fidouh, Nadhira, Valette, Martine, Mailles, Alexandra, Lucet, Jean-Christophe, Mentre, France, Duval, Xavier, Descamps, Diane, Malvy, Denis, Timsit, Jean-François, Lina, Bruno, van-der-Werf, Sylvie, Yazdanpanah, Yazdan

“…On Dec 31, 2019, China reported a cluster of cases of pneumonia in people at Wuhan, Hubei Province. The responsible pathogen is a novel coronavirus, named…”
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Association between mobility patterns and COVID-19 transmission in the USA: a mathematical modelling study by Badr, Hamada S, Du, Hongru, Marshall, Maximilian, Dong, Ensheng, Squire, Marietta M, Gardner, Lauren M

“…Within 4 months of COVID-19 first being reported in the USA, it spread to every state and to more than 90% of all counties. During this period, the US COVID-19…”
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Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of SARS-CoV-2 in different settings: a mathematical modelling study by Kucharski, Adam J, Klepac, Petra, Conlan, Andrew J K, Kissler, Stephen M, Tang, Maria L, Fry, Hannah, Gog, Julia R, Edmunds, W John, Emery, Jon C, Medley, Graham, Munday, James D, Russell, Timothy W, Leclerc, Quentin J, Diamond, Charlie, Procter, Simon R, Gimma, Amy, Sun, Fiona Yueqian, Gibbs, Hamish P, Rosello, Alicia, van Zandvoort, Kevin, Hué, Stéphane, Meakin, Sophie R, Deol, Arminder K, Knight, Gwen, Jombart, Thibaut, Foss, Anna M, Bosse, Nikos I, Atkins, Katherine E, Quilty, Billy J, Lowe, Rachel, Prem, Kiesha, Flasche, Stefan, Pearson, Carl A B, Houben, Rein M G J, Nightingale, Emily S, Endo, Akira, Tully, Damien C, Liu, Yang, Villabona-Arenas, Julian, O'Reilly, Kathleen, Funk, Sebastian, Eggo, Rosalind M, Jit, Mark, Rees, Eleanor M, Hellewell, Joel, Clifford, Samuel, Jarvis, Christopher I, Abbott, Sam, Auzenbergs, Megan, Davies, Nicholas G, Simons, David

“…The isolation of symptomatic cases and tracing of contacts has been used as an early COVID-19 containment measure in many countries, with additional physical…”
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COVID-19: combining antiviral and anti-inflammatory treatments by Stebbing, Justin, Phelan, Anne, Griffin, Ivan, Tucker, Catherine, Oechsle, Olly, Smith, Dan, Richardson, Peter

“…Both coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome (SARS) are characterised by an overexuberant inflammatory response and, for…”
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The value of antimicrobial peptides in the age of resistance by Magana, Maria, Pushpanathan, Muthuirulan, Santos, Ana L, Leanse, Leon, Fernandez, Michael, Ioannidis, Anastasios, Giulianotti, Marc A, Apidianakis, Yiorgos, Bradfute, Steven, Ferguson, Andrew L, Cherkasov, Artem, Seleem, Mohamed N, Pinilla, Clemencia, de la Fuente-Nunez, Cesar, Lazaridis, Themis, Dai, Tianhong, Houghten, Richard A, Hancock, Robert E W, Tegos, George P

“…Accelerating growth and global expansion of antimicrobial resistance has deepened the need for discovery of novel antimicrobial agents. Antimicrobial peptides…”
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Genomic evidence for reinfection with SARS-CoV-2: a case study by Tillett, Richard L, Sevinsky, Joel R, Hartley, Paul D, Kerwin, Heather, Crawford, Natalie, Gorzalski, Andrew, Laverdure, Chris, Verma, Subhash C, Rossetto, Cyprian C, Jackson, David, Farrell, Megan J, Van Hooser, Stephanie, Pandori, Mark

“…The degree of protective immunity conferred by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the…”
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Convalescent plasma as a potential therapy for COVID-19 by Chen, Long, Xiong, Jing, Bao, Lei, Shi, Yuan

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Can we contain the COVID-19 outbreak with the same measures as for SARS? by Wilder-Smith, Annelies, Chiew, Calvin J, Lee, Vernon J

“…The severe acute respiratory syndrome (SARS) outbreak in 2003 resulted in more than 8000 cases and 800 deaths. SARS was eventually contained by means of…”
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What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2 by Hodgson, Susanne H, Mansatta, Kushal, Mallett, Garry, Harris, Victoria, Emary, Katherine R W, Pollard, Andrew J

“…The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused more than 1 million deaths in the first 6 months of the…”
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