Search Results - "Thayer, Desiree A"

Structural and Mechanistic Regulation of the Pro-degenerative NAD Hydrolase SARM1 by Bratkowski, Matthew, Xie, Tian, Thayer, Desiree A., Lad, Shradha, Mathur, Prakhyat, Yang, Yu-San, Danko, Gregory, Burdett, Thomas C., Danao, Jean, Cantor, Aaron, Kozak, Jennifer A., Brown, Sean P., Bai, Xiaochen, Sambashivan, Shilpa

“…The NADase SARM1 is a central switch in injury-activated axon degeneration, an early hallmark of many neurological diseases. Here, we present cryo-electron…”
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Increased neuronal activity fragments the Golgi complex by Thayer, Desiree A., Jan, Yuh Nung, Jan, Lily Yeh

“…The Golgi complex is essential for many aspects of cellular function, including trafficking and sorting of membrane and secretory proteins and…”
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N‐linked glycosylation of Kv1.2 voltage‐gated potassium channel facilitates cell surface expression and enhances the stability of internalized channels by Thayer, Desiree A., Yang, Shi‐Bing, Jan, Yuh Nung, Jan, Lily Y.

“…Key points Kv1.2 and related voltage‐gated potassium channels have a highly conserved N‐linked glycosylation site in the first extracellular loop, with complex…”
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Carbohydrate Microarray for Profiling the Antibodies Interacting with Globo H Tumor Antigen by Huang, Cheng-Yuan, Thayer, Desiree A., Chang, Aileen Y., Best, Michael D., Hoffmann, Julia, Head, Steve, Wong, Chi-Huey

“…Understanding the specificity of cell-surface carbohydrates interaction with antibodies and receptors is important for the development of new therapeutics and…”
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DNA Detection and Signal Amplification via an Engineered Allosteric Enzyme by Saghatelian, Alan, Guckian, Kevin M, Thayer, Desiree A, Ghadiri, M. Reza

“…Rapid, sensitive, and sequence-specific DNA detection can be achieved in one step using an engineered intrasterically regulated enzyme. The semi-synthetic…”
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The Caulobacter crescentus CgtAC Protein Cosediments with the Free 50S Ribosomal Subunit by Lin, Bin, Thayer, Desiree A, Maddock, Janine R

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging by Yu, Dan, Gustafson, William Clay, Han, Chun, Lafaye, Céline, Noirclerc-Savoye, Marjolaine, Ge, Woo-Ping, Thayer, Desiree A., Huang, Hai, Kornberg, Thomas B., Royant, Antoine, Jan, Lily Yeh, Jan, Yuh Nung, Weiss, William A., Shu, Xiaokun

“…Infrared fluorescent proteins (IFPs) are ideal for in vivo imaging, and monomeric versions of these proteins can be advantageous as protein tags or for sensor…”
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Vancomycin Analogues Containing Monosaccharides Exhibit Improved Antibiotic Activity: A Combined One-Pot Enzymatic Glycosylation and Chemical Diversification Strategy by Thayer, Desiree A., Wong , Chi-Huey

“…Many natural products contain carbohydrate moieties that contribute to their biological activity. Manipulation of the carbohydrate domain of natural products…”
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Antibacterial cyclic D,L-alpha-glycopeptides by Motiei, Leila, Rahimipour, Shai, Thayer, Desiree A, Wong, Chi-Huey, Ghadiri, M Reza

“…We report the design, synthesis, membrane activity, biophysical characterization, and in vitro antibacterial activities of cationic cyclic…”
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A General Strategy toward S-Linked Glycopeptides by Thayer, Desiree A., Yu, Henry N., Galan, M. Carmen, Wong, Chi-Huey

“…A high‐yield one‐pot synthesis of S‐linked glycosyl amino acids 1 has been developed (see scheme; DMF=dimethyl formamide) and used in the solid‐phase synthesis…”
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Mechanisms of distribution and targeting of neuronal ion channels by Thayer, Desiree A, Jan, Lily Y

“…The discovery and development of pharmaceutical drugs targeting ion channels is important for treating a variety of medical conditions and diseases. Ion…”
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Macrolactamization of Glycosylated Peptide Thioesters by the Thioesterase Domain of Tyrocidine Synthetase by Lin, Hening, Thayer, Desiree A., Wong, Chi-Huey, Walsh, Christopher T.

“…The 35 kDa thioesterase (TE) domain excised from the megadalton tyrocidine synthetase (Tyc Syn) retains autonomous capacity to macrocyclize peptidyl thioesters…”
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The Caulobacter crescentus CgtA C Protein Cosediments with the Free 50S Ribosomal Subunit by Lin, Bin, Thayer, Desiree A., Maddock, Janine R.

“…ABSTRACT The Obg family of GTPases is widely conserved and predicted to play an as-yet-unknown role in translation. Recent reports provide circumstantial…”
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Effects of glycans on peptide antibiotics and analytical methods for carbohydrate sequencing and binding interactions by Thayer, Desiree A

“…I. Altered glycosylation of peptide antibiotics-synthesis and improved biological activity. A variety of nonribosomal peptide and glycopeptide natural products…”
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A General Strategy toward S-Linked Glycopeptides by Thayer, Desiree A., Yu, Henry N., Galan, M. Carmen, Wong, Chi-Huey

“…Eine effiziente Eintopfsynthese von S‐verknüpften Glycosylaminosäuren 1 wurde entwickelt (siehe Schema; DMF=Dimethylformamid) und in der Festphasensynthese von…”
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A General Strategy toward S‐Linked Glycopeptides by Thayer, Desiree A., Yu, Henry N., Galan, M. Carmen, Wong, Chi‐Huey

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