Search Results - "Thasler, W"

Effects of atorvastatin metabolites on induction of drug‐metabolizing enzymes and membrane transporters through human pregnane X receptor by Hoffart, E, Ghebreghiorghis, L, Nussler, AK, Thasler, WE, Weiss, TS, Schwab, M, Burk, O

“…BACKGROUND AND PURPOSE Atorvastatin metabolites differ in their potential for drug interaction because of differential inhibition of drug‐metabolizing enzymes…”
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Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes by Garten, A., Petzold, S., Barnikol-Oettler, A., Körner, A., Thasler, W.E., Kratzsch, J., Kiess, W., Gebhardt, R.

“…Circulating NAMPT (PBEF/visfatin) has pleiotropic functions and is secreted from adipocytes. Since it is doubtful whether serum levels can be explained by…”
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Increased Expression of Histone Deacetylase 7 during Hepatic Stellate Cell Activation Promotes Pro-Fibrogenic Gene Expression by Freese, K, Dorn, C, Thasler, W, Müller, M, Hellerbrand, C

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Hepatic progenitor cells from adult human livers for cell transplantation by Weiss, T S, Lichtenauer, M, Kirchner, S, Stock, P, Aurich, H, Christ, B, Brockhoff, G, Kunz-Schughart, L A, Jauch, K-W, Schlitt, H-J, Thasler, W E

“…Liver regeneration is mainly based on cellular self-renewal including progenitor cells. Efforts have been made to harness this potential for cell…”
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JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand by Mucha, S R, Rizzani, A, Gerbes, A L, Camaj, P, Thasler, W E, Bruns, C J, Eichhorst, S T, Gallmeier, E, Kolligs, F T, Göke, B, De Toni, E N

“…cJun terminal kinase (JNK) is constitutively activated in most hepatocellular carcinomas (HCCs), yet its exact role in carcinogenesis remains controversial…”
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Decrease of global methylation improves significantly hepatic differentiation of Ad-MSCs: possible future application for urea detoxification by Seeliger, C, Culmes, M, Schyschka, L, Yan, X, Damm, G, Wang, Z, Kleeff, J, Thasler, W E, Hengstler, J, Stöckle, U, Ehnert, S, Nüssler, A K

“…Hepatocyte transplantation is considered to be an alternative to orthotopic liver transplantation. Cells can be used to bridge patients waiting for a donor…”
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P1115 : ERK And P38 activation are central mediators of irinotecan-induced steatohepatitis by Mahli, A, Saugspier, M, Thasler, W, Müller, M, Bosserhoff, A, Hellerbrand, C

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P0278 : Hepatic steatosis and high circulating free fatty acid levels promote growth and invasiveness of hepatocellular carcinoma by Koch, A, Dorn, C, Thasler, W, Mïller, M, Bosserhoff, A, Hellerbrand, C

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Analysis of Molecular Mechanisms of 5-Fluorouracil Induced Steatosis and Inflammation in Vitro and in Mice by Sommer, J, Mahli, A, Freese, K, Thasler, W, Kuecuekoktay, F, Bosserhoff, A, Müller, M, Hellerbrand, C

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Expression of augmenter of liver regeneration (ALR) in human liver cirrhosis and carcinoma by Thasler, W E, Schlott, T, Thelen, P, Hellerbrand, C, Bataille, F, Lichtenauer, M, Schlitt, H-J, Jauch, K-W, Weiss, T S

“…Aims : To determine the expression of a protein termed augmenter of liver regeneration (ALR), recently found to have a specific and beneficial effect on the…”
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STAT3 inhibition reduces toxicity of oncolytic VSV and provides a potentially synergistic combination therapy for hepatocellular carcinoma by Marozin, S, Altomonte, J, Muñoz-Álvarez, K A, Rizzani, A, De Toni, E N, Thasler, W E, Schmid, R M, Ebert, O

“…Hepatocellular carcinoma (HCC) is a refractory malignancy with a high mortality and increasing worldwide incidence rates, including the United States and…”
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Randomized controlled multicenter trial on the effectiveness of the collagen hemostat Sangustop® compared with a carrier-bound fibrin sealant during liver resection (ESSCALIVER study, NCT00918619) by Moench, C., Mihaljevic, A. L., Hermanutz, V., Thasler, W. E., Suna, K., Diener, M. K., Seehofer, D., Mischinger, H. J., Jansen-Winkeln, B., Knaebel, H. P., Bechstein, W. O.

“…Background Despite improvements in liver surgery over the past decades, hemostasis during hepatic resections remains challenging. This multicenter randomized…”
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Passion and commensurability: both are needed for a concurrence of surgery and research by Thasler, W. E., Kleespies, A., Thasler, R., Jauch, K.-W.

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Collagen sandwich culture affects intracellular polyamine levels of human hepatocytes by Weiss, T. S., Jahn, B., Cetto, M., Jauch, K.-W., Thasler, W. E.

“… Extracellular matrices, like collagen layers, play an important role in preventing dedifferentiation of hepatocytes in long‐term culture experiments. It has…”
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Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes by Beuers, U, Throckmorton, DC, Anderson, MS, Isales, CM, Thasler, W, Kullak-Ublick, GA, Sauter, G, Koebe, HG, Paumgartner, G, Boyer, JL

“…BACKGROUND & AIMS: Ursodeoxycholic acid (UDCA) improves liver function in patients with chronic cholestatic liver diseases by an unknown mechanism. UDCA is…”
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Acute pancreatitis: is there a need for surgery? by Kleespies, A, Thasler, W E, Schäfer, C, Meimarakis, G, Eichhorn, M E, Bruns, C J, Jauch, K-W, Zügel, N

“…The treatment of acute pancreatitis is primarily non-surgical. An interdisciplinary approach as well as timely and aggressive intensive care has led to a…”
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Interdisciplinary diagnosis of and therapy for cholangiocarcinoma by Kolligs, F T, Zech, C J, Schönberg, S O, Schirra, J, Thasler, W, Graeb, C, Beuers, U, Wilkowski, R, Jacobs, T, Böck, S, Berster, J, Heinemann, V, Schäfer, C

“…The diagnosis of and therapy for cholangiocarcinomas still remains an interdisciplinary challenge. For diagnostic and therapeutic purposes intra- and…”
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Hepatic steatosis potentiates irinotecan-induced hepatocellular injury via dysregulation of irinotecan-metabolizing enzymes by Mahli, A., Koch, A., Thasler, W., Hellerbrand, C.

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THU-507 - Hepatic steatosis potentiates irinotecan-induced hepatocellular injury via dysregulation of irinotecan-metabolizing enzymes by Mahli, A., Koch, A., Thasler, W., Hellerbrand, C.

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Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene by Zhou, Dawang, Conrad, Claudius, Xia, Fan, Park, Ji-Sun, Payer, Bernhard, Yin, Yi, Lauwers, Gregory Y., Thasler, Wolfgang, Lee, Jeannie T., Avruch, Joseph, Bardeesy, Nabeel

“…Hippo-Lats-Yorkie signaling regulates tissue overgrowth and tumorigenesis in Drosophila. We show that the Mst1 and Mst2 protein kinases, the mammalian Hippo…”
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