Search Results - "Tharin, Zoé"

The Role of Molecular Profiling to Predict the Response to Immune Checkpoint Inhibitors in Lung Cancer by Kaderbhaï, Courèche, Tharin, Zoé, Ghiringhelli, François

“…Immune checkpoint inhibitors radically changed the treatment of patients with non-small cell lung cancer (NSCLC). However, only one-quarter of patients benefit…”
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PIK3CA and PIK3R1 tumor mutational landscape in a pan-cancer patient cohort and its association with pathway activation and treatment efficacy by Tharin, Zoé, Richard, Corentin, Derangère, Valentin, Ilie, Alis, Arnould, Laurent, Ghiringhelli, François, Boidot, Romain, Ladoire, Sylvain

“…There is little data concerning the implications of PIK3CA mutations outside of the known hotspots described in ER+/HER2− metastatic breast cancer (mBC)…”
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Folfirinox in elderly patients with pancreatic or colorectal cancer-tolerance and efficacy by Guion-Dusserre, Jean-Florian, Bertaut, Aurélie, Ghiringhelli, François, Vincent, Julie, Quipourt, Valérie, Marilier, Sophie, Tharin, Zoé, Bengrine-Lefevre, Leila

“…AIM To study the tolerance and the efficiency of FOLFIRINOX in elderly patients diagnosed with colorectal or pancreatic cancer.METHODS This retrospective study…”
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Using Exome Sequencing to Improve Prediction of FOLFIRINOX First Efficacy for Pancreatic Adenocarcinoma by Lecuelle, Julie, Aarnink, Anne, Tharin, Zoé, Truntzer, Caroline, Ghiringhelli, François

“…The first line treatment of advanced pancreatic ductal adenocarcinoma cancer (PDAC) comprises a FOLFIRINOX regimen for most patients with good performance…”
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Influence of first line chemotherapy strategy depending on primary tumor location in metastatic colorectal cancer by Tharin, Zoé, Blanc, Julie, Alaoui, Ikram Charifi, Bertaut, Aurélie, Ghiringhelli, Francois

“…Primary tumor location (PTL) is a major prognostic factor in metastatic colorectal cancer (mCRC) with left side which present better prognosis than right…”
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Pharmacokinetic/Pharmacodynamic Model of Neutropenia in Real-Life Palbociclib-Treated Patients by Marouille, Alexandre, Petit, Emma, Kaderbhaï, Courèche, Desmoulins, Isabelle, Hennequin, Audrey, Mayeur, Didier, Fumet, Jean-David, Ladoire, Sylvain, Tharin, Zoé, Ayati, Siavoshe, Ilie, Silvia, Royer, Bernard, Schmitt, Antonin

“…Palbociclib is an oral CDK4/6 inhibitor indicated in HR+/HER2- advanced or metastatic breast cancer in combination with hormonotherapy. Its main toxicity is…”
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Smartphone-based application and nurses’ interventions for symptoms monitoring in patients treated with oral anticancer agents: A 1-year follow-up in a tertiary cancer center by Porcher, Laura, Perron, Valérie, Blanc, Julie, Kaderbhai, Courèche-Guillaume, Tharin, Zoé, Schmitt, Antonin, Gallet, Matthieu

“…Aim The increasing use of oral anticancer agents over the past years has necessitated changes in monitoring toxicities to ensure patients’ adherence and…”
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TCR Clonality and Genomic Instability Signatures as Prognostic Biomarkers in High Grade Serous Ovarian Cancer by Lecuelle, Julie, Boidot, Romain, Mananet, Hugo, Derangère, Valentin, Albuisson, Juliette, Goussot, Vincent, Arnould, Laurent, Tharin, Zoé, Ray Coquard, Isabelle, Ghiringhelli, François, Truntzer, Caroline, Fumet, Jean-David

“…Immune infiltration is a prognostic factor in high-grade serous ovarian carcinoma (HGSC) but immunotherapy efficacy is disappointing. Genomic instability is…”
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Influence of primary tumor location and resection on survival in metastatic colorectal cancer by Tharin, Zoé, Blanc, Julie, Alaoui, Ikram Charifi, Bertaut, Aurélie, Ghiringhelli, François

“…BACKGROUNDPatients with right sided colorectal cancer are known to have a poorer prognosis than patients with left sided colorectal cancer, whatever the cancer…”
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Alpelisib and fulvestrant in PIK3CA-mutated hormone receptor-positive HER2-negative advanced breast cancer included in the French early access program by Bello Roufai, D., Gonçalves, A., De La Motte Rouge, T., Akla, S., Blonz, C., Grenier, J., Gligorov, J., Saghatchian, M., Bailleux, C., Simon, H., Desmoulins, I., Tharin, Z., Renaud, E., Bertho, M., Benderra, M-A, Delaloge, S., Robert, L., Cottu, P., Pierga, J. Y., Loirat, D., Bertucci, A., Renouf, B., Bidard, F. C., Lerebours, F.

“…SOLAR-1 and BYLieve trials documented the efficacy of the PI3K-inhibitor alpelisib in pre-treated PIK3CA -mutant, hormone receptor-positive, HER2-negative…”
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Alpelisib and fulvestrant efficacy in HR-positive HER2-negative PIK3CA -mutant advanced breast cancer: Data from the French early access program by Bello, Diana, Bertucci, Alexandre, De La Motte Rouge, Thibault, Blonz, Cyriac, Akla, Sarra, Grenier, Julien, Bailleux, Caroline, Benderra, Marc Antoine, Simon, Helene, Desmoulins, Isabelle, Tharin, Zoé, Renaud, Emmanuelle, Delaloge, Suzette, Bertho, Marion, Cottu, Paul H., Goncalves, Anthony, Bidard, François-Clément, Lerebours, Florence

“…Abstract only 1064 Background: In 11.2018, the PIK3CA-inhibitor alpelisib was made available in France through an early access program (EAP), in combination…”
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RCP soins de support : 12 ans d’expérience d’un centre de lutte contre le cancer by Favier, Laure, Bremaud, Nathalie, Tharin, Zoé, Blanc, Julie, Bertaut, Aurélie, Alavoine, Véronique, Dubief, A., Truc, Gilles, Dorlean, Christine, Coudert, Bruno

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Biologie moléculaire des carcinomes bronchiques : standards actuels et perspectives by Tharin, Zoé, Kaderbhaï, Courèche, Ghiringhelli, François

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RCP soins de support : 12 ans d’expérience d’un centre de lutte contre le cancer by Favier, Laure, Bremaud, Nathalie, Tharin, Zoé, Blanc, Julie, Bertaut, Aurélie, Alavoine, Véronique, Dubief, A., Truc, Gilles, Dorlean, Christine, Coudert, Bruno

“…En 2006, à la suite de la circulaire DHOS 2005/101, nous avons créé une réunion multidisciplinaire de soins de support. Il existe très peu de données dans la…”
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Utility of exome sequencing in routine care for metastatic colorectal cancer by D'agay, Melchior De Giraud, Galland, Loick, Tharin, Zoe, Truntzer, Caroline, Ghiringhelli, Francois

“…Metastatic colorectal cancer (mCRC) is a heterogenous disease and its prognosis depends on clinical features, such as tumor sidedness, and whether it is…”
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