Search Results - "Thangapazham, Rajesh L"

Skin regenerative potentials of curcumin by Thangapazham, Rajesh L., Sharad, Shashwat, Maheshwari, Radha K.

“…Curcumin, an active constituent of the spice turmeric, is well known for its chemopreventive properties and is found to be beneficial in treating various…”
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Curcumin-Gene Expression Response in Hormone Dependent and Independent Metastatic Prostate Cancer Cells by Katta, Shilpa, Srivastava, Arun, Thangapazham, Rajesh L, Rosner, Inger L, Cullen, Jennifer, Li, Hua, Sharad, Shashwat

“…The androgen receptor is one of the key targets for prostate cancer treatment. Despite its less satisfactory effects, chemotherapy is the most common treatment…”
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Alteration of skin properties with autologous dermal fibroblasts by Thangapazham, Rajesh L, Darling, Thomas N, Meyerle, Jon

“…Dermal fibroblasts are mesenchymal cells found between the skin epidermis and subcutaneous tissue. They are primarily responsible for synthesizing collagen and…”
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Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo by Thangapazham, Rajesh L, Singh, Anoop K, Sharma, Anuj, Warren, James, Gaddipati, Jaya P, Maheshwari, Radha K

“…Abstract Tea [ Camellia sinensis (Theaceae)] intake is second only to water in terms of worldwide popularity as a beverage. The Green tea polyphenols have been…”
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Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites by Thangapazham, Rajesh L., Klover, Peter, Wang, Ji-an, Zheng, Ying, Devine, Amanda, Li, Shaowei, Sperling, Leonard, Cotsarelis, George, Darling, Thomas N.

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Green tea polyphenol and epigallocatechin gallate induce apoptosis and inhibit invasion in human breast cancer cells by Thangapazham, Rajesh L., Passi, Neena, Maheshwari, Radha K.

“…Currently, there is no effective therapy for estrogen independent breast cancer. MDA-MB-231 is an estrogen receptor negative highly invasive human breast…”
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Delineation of TMPRSS2-ERG Splice Variants in Prostate Cancer by YING HU, DOBI, Albert, MOHAMED, Ahmed, CHEN SUN, SESTERHENN, Isabell A, MCLEOD, David G, PETROVICS, Gyorgy, SRIVASTAVA, Shiv, SREENATH, Taduru, COOK, Christopher, TADASE, Atekelt Y, RAVINDRANATH, Lakshmi, CULLEN, Jennifer, FURUSATO, Bungo, YONGMEI CHEN, THANGAPAZHAM, Rajesh L

“…Purpose: The expression of the ETS -related gene ( ERG ) is low or undetectable in benign prostate epithelial cells. High prevalence of ERG overexpression in…”
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Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury by McCart, Elizabeth A, Thangapazham, Rajesh L, Lombardini, Eric D, Mog, Steven R, Panganiban, Ronald Allan M, Dickson, Kelley M, Mansur, Rihab A, Nagy, Vitaly, Kim, Sung-Yop, Selwyn, Reed, Landauer, Michael R, Darling, Thomas N, Day, Regina M

“…Abstract Accidental high-dose radiation exposures can lead to multi-organ injuries, including radiation dermatitis. The types of cellular damage leading to…”
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Tsc2 disruption in mesenchymal progenitors results in tumors with vascular anomalies overexpressing Lgals3 by Klover, Peter J, Thangapazham, Rajesh L, Kato, Jiro, Wang, Ji-An, Anderson, Stasia A, Hoffmann, Victoria, Steagall, Wendy K, Li, Shaowei, McCart, Elizabeth, Nathan, Neera, Bernstock, Joshua D, Wilkerson, Matthew D, Dalgard, Clifton L, Moss, Joel, Darling, Thomas N

“…Increased mTORC1 signaling from inactivation is found in cancer and causes tuberous sclerosis complex (TSC). The role of mesenchymal-derived cells in TSC…”
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Androgen responsive and refractory prostate cancer cells exhibit distinct curcumin regulated transcriptome by Thangapazham, Rajesh L., Shaheduzzaman, Syed, Kim, Kee-Hong, Passi, Neena, Tadese, Atekelt, Vahey, Maryanne, Dobi, Albert, Srivastava, Shiv, Maheshwari, Radha K.

“…Curcumin (diferuloylmethane) is the major active component of turmeric and is being actively investigated for its anti-cancer properties. To better understand…”
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Multiple molecular targets in cancer chemoprevention by curcumin by Thangapazham, Rajesh L, Sharma, Anuj, Maheshwari, Radha K

“…Carcinogenesis encompasses 3 closely associated stages: initiation, progression, and promotion. Phytochemicals are nonnutritive components of plants that are…”
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Shikonin analogue (SA) 93/637 induces apoptosis by activation of caspase-3 in U937 cells by Thangapazham, Rajesh L, Singh, Anoop K, Seth, Pankaj, Misra, Namita, Mathad, Vijayavitthal T, Raj, Kanwal, Maheshwari, Radha K

“…Beta,beta-dimethyl acryl shikonin is an extract from the root of plant Arnebia nobilis which has been shown to possess anti-cancer activity. However, its…”
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Evaluation of a nanotechnology-based carrier for delivery of curcumin in prostate cancer cells by THANGAPAZHAM, Rajesh L, PURI, Anu, TELE, Shrikant, BLUMENTHAL, Robert, MAHESHWARI, Radha K

“…We have initiated studies to enhance targeted delivery of an anticancer agent, curcumin, for prostate cancer treatment by incorporating this agent into the…”
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Beneficial role of curcumin in skin diseases by Thangapazham, Rajesh L, Sharma, Anuj, Maheshwari, Radha K

“…In recent years, considerable interest has been focused on curcumin a compound, isolated from turmeric. Curcumin is used as a coloring, flavoring agent and has…”
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A model system to analyse the ability of human keratinocytes to form hair follicles by Thangapazham, Rajesh L., Klover, Peter, Li, Shaowei, Wang, Ji-an, Sperling, Leonard, Darling, Thomas N.

“…Earlier studies showed that dermal cells lose trichogenic capacity with passage, but studies on the effect of keratinocyte passage on human hair follicle…”
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Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis by Darling, Thomas N, Li, Shaowei, Thangapazham, Rajesh L, Wang, Ji-an, Rajesh, Sangeetha, Kao, Tzu-Cheg, Sperling, Leonard, Moss, Joel

“…Hamartomas are composed of cells native to an organ but abnormal in number, arrangement or maturity. In the tuberous sclerosis complex (TSC), hamartomas…”
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Differential Regulation of Angiogenic Genes in Diabetic Wound Healing by Sharma, Anuj, Singh, Anoop K., Warren, James, Thangapazham, Rajesh L., Maheshwari, Radha K.

“…Wound healing is a complicated biological process that involves interactions of multiple cell types, various growth factors, their mediators, and the…”
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Picroliv accelerates epithelialization and angiogenesis in rat wounds by Singh, Anoop K, Sharma, Anuj, Warren, James, Madhavan, Subhashree, Steele, Keith, RajeshKumar, N V, Thangapazham, Rajesh L, Sharma, Shekhar C, Kulshreshtha, Dinesh K, Gaddipati, Jaya, Maheshwari, Radha K

“…Tissue repair and wound healing are complex processes that involve inflammation, granulation and tissue remodeling. Angiogenesis plays a central role in wound…”
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Homeopathic Medicines Do Not Alter Growth and Gene Expression in Prostate and Breast Cancer Cells In Vitro by Thangapazham, Rajesh L., Gaddipati, Jaya P., Rajeshkumar, N. V., Sharma, Anuj, Singh, Anoop K., Ives, John A., Maheshwari, Radha K., Jonas, Wayne B.

“…Background: Homeopathy is an alternative medical system practiced in all parts of the world. Although several theories are proposed to explain the mechanisms…”
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Can Homeopathic Treatment Slow Prostate Cancer Growth? by Jonas, Wayne B., Gaddipati, Jaya P., Rajeshkumar, N. V., Sharma, Anuj, Thangapazham, Rajesh L., Warren, Jim, Singh, Anoop K., Ives, John A., Olsen, Cara, Mog, Steven R., Maheshwari, Radha K.

“…Background: Homeopathy is a complementary medicine widely used around the world. Despite extensive use of homeopathy for cancer and other serious conditions…”
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