Search Results - "Than, N G"

Evolutionary origins of the placental expression of chromosome 19 cluster galectins and their complex dysregulation in preeclampsia by Than, N.G, Romero, R, Xu, Y, Erez, O, Xu, Z, Bhatti, G, Leavitt, R, Chung, T.H, El-Azzamy, H, LaJeunesse, C, Wang, B, Balogh, A, Szalai, G, Land, S, Dong, Z, Hassan, S.S, Chaiworapongsa, T, Krispin, M, Kim, C.J, Tarca, A.L, Papp, Z, Bohn, H

“…Abstract Introduction The dysregulation of maternal-fetal immune tolerance is one of the proposed mechanisms leading to preeclampsia. Galectins are key…”
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The use of high‐dimensional biology (genomics, transcriptomics, proteomics, and metabolomics) to understand the preterm parturition syndrome by Romero, R, Espinoza, J, Gotsch, F, Kusanovic, JP, Friel, LA, Erez, O, Mazaki‐Tovi, S, Than, NG, Hassan, S, Tromp, G

“…High‐dimensional biology (HDB) refers to the simultaneous study of the genetic variants (DNA variation), transcription (messenger RNA [mRNA]), peptides and…”
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Clinical significance of the presence of amniotic fluid ‘sludge’ in asymptomatic patients at high risk for spontaneous preterm delivery by Kusanovic, J. P., Espinoza, J., Romero, R., Gonçalves, L. F., Nien, J. K., Soto, E., Khalek, N., Camacho, N., Hendler, I., Mittal, P., Friel, L. A., Gotsch, F., Erez, O., Than, N. G., Mazaki‐Tovi, S., Schoen, M. L., Hassan, S. S.

“…Objectives To determine the clinical significance of the presence of amniotic fluid (AF) ‘sludge’ among asymptomatic patients at high risk for spontaneous…”
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Microarray Profiling Reveals That Placental Transcriptomes of Early-onset HELLP Syndrome and Preeclampsia Are Similar by Várkonyi, T, Nagy, B, Füle, T, Tarca, A.L, Karászi, K, Schönléber, J, Hupuczi, P, Mihalik, N, Kovalszky, I, Rigó, J, Meiri, H, Papp, Z, Romero, R, Than, N.G

“…Abstract Background The involvement of the placenta in the pathogenesis of preeclampsia and HELLP syndrome is well established, and placental lesions are also…”
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Prediction of Preeclampsia – A Workshop Report by Than, N.G, Romero, R, Hillermann, R, Cozzi, V, Nie, G, Huppertz, B

“…Abstract Understanding the mechanisms of disease responsible for the syndrome of preeclampsia as well as early risk assessment is still a major challenge. The…”
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Isolation and Sequence Analysis of a cDNA Encoding Human Placental Tissue Protein 13 (PP13), a New Lysophospholipase, Homologue of Human Eosinophil Charcot-Leyden Crystal Protein by Than, N.G, Sumegi, B, Than, G.N, Berente, Z, Bohn, H

“…Expression of placental tissue protein 13 (PP13) in different human tissues was investigated by chemiluminescence Western blot analysis using monospecific…”
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Plasma soluble endoglin concentration in pre‐eclampsia is associated with an increased impedance to flow in the maternal and fetal circulations by Chaiworapongsa, T., Romero, R., Kusanovic, J. P., Mittal, P., Kim, S. K., Gotsch, F., Than, N. G., Mazaki‐Tovi, S., Vaisbuch, E., Erez, O., Yeo, L., Hassan, S. S., Sorokin, Y.

“…Objectives To examine the relationship between abnormalities in uterine (UtA) and/or umbilical artery (UA) Doppler velocimetry and maternal plasma…”
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“Trophoblast islands of the chorionic connective tissue” (TICCT): A novel placental histologic feature by Hong, J.-S, Romero, R, Kusanovic, J.P, Kim, J.-S, Lee, J, Jin, M, El Azzamy, H, Lee, D.-C, Topping, V, Ahn, S, Jacques, S, Qureshi, F, Chaiworapongsa, T, Hassan, S.S, Korzeniewski, S.J, Than, N.G, Kim, C.J

“…Abstract Introduction We found isolated or clustered trophoblasts in the chorionic connective tissue of the extraplacental membranes, and defined this novel…”
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Homology modelling and molecular dynamics studies of human placental tissue protein 13 (galectin-13) by Visegrády, Balázs, Than, Nándor G., Kilár, Ferenc, Sümegi, Balázs, Than, Gábor N., Bohn, Hans

“…The primary structure of the newly sequence analysed placental tissue protein 13 (PP13) was highly homologous to several members of the β-galactoside-binding…”
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The role of neutrophil activation in determining the outcome of pregnancy and modulation by hormones and/or cytokines by Hahn, S., Hasler, P., Vokalova, L., van Breda, S. V., Lapaire, O., Than, N. G., Hoesli, I., Rossi, S. W.

“…Summary Neutrophils are often exclusively considered as a first‐line innate immune defence, able to rapidly kill or trap pathogens and causing in case of…”
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Cloning, sequencing, structural and molecular biological characterization of placental protein 20 (PP20)/human thiamin pyrophosphokinase (hTPK) by Bellyei, Sz, Szigeti, A., Boronkai, A., Szabo, Z., Bene, J., Janaky, T., Barna, L., Sipos, K., Minik, O., Kravjak, A., Ohmacht, R., Melegh, B., Zavodszky, P., Than, G.N., Sumegi, B., Bohn, H., Than, N.G.

“…Full-length cDNAs of placental protein 20 (PP20) were cloned by screening a human placental cDNA library, which encode a 243 amino acid protein, identical to…”
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Embryo–Placento–Maternal Interaction and Biomarkers: From Diagnosis to Therapy – A Workshop Report by Than, N.G, Paidas, M.J, Mizutani, S, Sharma, S, Padbury, J, Barnea, E.R

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Molecular Cloning and Characterization of Placental Tissue Protein 18 (PP18a)/Human Mitochondrial Branched-chain Aminotransferase (BCATm) and its Novel Alternatively Spliced PP18b Variant by Than, N.G, Sümegi, B, Than, G.N, Bellyei, Sz, Bohn, H

“…Five different insert-length cDNAs encoding for soluble placental tissue protein 18 (PP18) variants were isolated by screening a human placental cDNA library…”
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Extremely high maternal alkaline phosphatase serum concentration with syncytiotrophoblastic origin by Boronkai, A, Than, N G, Magenheim, R, Bellyei, S, Szigeti, A, Deres, P, Hargitai, B, Sumegi, B, Papp, Z, Rigo, J

“…An extremely high alkaline phosphatase (AP) concentration (3609 IU/litre) was found in a 20 year old primigravida at 37 week’s gestation, prompting an…”
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Overexpression of placental tissue protein 17b/TIP47 in cervical dysplasias and cervical carcinoma by Than, G N, Turóczy, T, Sümegi, B, Than, N G, Bellyei, S, Bohn, H, Szekeres, G

“…In our previous Western- and Northern-blot investigations, high over-expression of placental protein 17b/TIP47 was detected in extracts of human cervical…”
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Is placental tissue protein 17b/TIP47 a new factor in cervical cancer genesis? by Than, N G, Sumegi, B, Than, G N, Kispal, G, Bohn, H

“…We identified novel members of the placental tissue protein 17 (PP17) protein family which consists of different-size variants of PP17; cDNAs of PP17a and…”
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Clinical Applications of Pregnancy-Related Proteins—A Workshop Report by Than, N.G., Itakura, A., Rao, Ch.V., Nohira, T., Toth, P., Mansell, J.P., Isaka, K., Nishi, H., Takayama, M., Than, G.N.

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Tumor markers (pregnancy protein 1, placental-specific tissue protein 10, placental-specific tissue protein 12, α1-Fetovrotein) in patients with bronchial carcinoma by BRIESE, V, SZABO, D. G, THAN, G. N, WILLROTH, P. O, BRIESE, J

“…The concentrations of pregnancy protein 1 (SP1), placental-specific tissue protein 10 (PP10), placental-specific tissue protein 12 (PP12) and…”
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Cloning and sequencing of human oncodevelopmental soluble placental tissue protein 17 (PP17): homology with adipophilin and the mouse adipose differentiation-related protein by Than, N G, Sumegi, B, Than, G N, Kispal, G, Bohn, H

“…Using a monospecific anti-PP17 antiserum, we detected 4 different molecular-weight PP17 immunoreactive proteins (31,500 kD PP17a, 48, 000 kD PP17b, 60,900 kD…”
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Application of Pregnancy-related Proteins in Prenatal and Tumor Diagnostics – A Workshop Report by Than, N.G., Nagai, A., Sharma, S., Meiri, H., Hauguel-de Mouzon, S., Sadovsky, Y., Rao, Ch.V.

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