Search Results - "Thamodaran, Vasanth"
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Establishment and characterization of CSCRi006-A: an induced pluripotent stem cell line generated from a patient with Diamond-Blackfan Anemia (DBA) carrying ribosomal protein S19 (RPS19) mutation
Published in Human cell : official journal of Human Cell Research Society (01-11-2023)“…Diamond-Blackfan anemia (DBA) is a congenital hypoplastic anemia characterized by ineffective erythropoiesis. DBA is majorly caused by mutations in the…”
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p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development
Published in Open biology (01-09-2016)“…During mouse preimplantation embryo development, the classically described second cell-fate decision involves the specification and segregation, in blastocyst…”
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p38-Mitogen Activated Kinases Mediate a Developmental Regulatory Response to Amino Acid Depletion and Associated Oxidative Stress in Mouse Blastocyst Embryos
Published in Frontiers in cell and developmental biology (08-11-2019)“…Maternal starvation coincident with preimplantation development has profound consequences for placental-fetal development, with various identified pathologies…”
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Direct Generation of Immortalized Erythroid Progenitor Cell Lines from Peripheral Blood Mononuclear Cells
Published in Cells (Basel, Switzerland) (01-03-2021)“…Reliable human erythroid progenitor cell (EPC) lines that can differentiate to the later stages of erythropoiesis are important cellular models for studying…”
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Efficient deletion of microRNAs using CRISPR/Cas9 with dual guide RNAs
Published in Frontiers in molecular biosciences (02-04-2024)“…MicroRNAs (miRNAs) are short non-coding RNAs that play crucial roles in gene regulation, exerting post-transcriptional silencing, thereby influencing cellular…”
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Gene Editing in Human Induced Pluripotent Stem Cells Using Doxycycline-Inducible CRISPR-Cas9 System
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Induced pluripotent stem cells (iPSCs) generated from patients are a valuable tool for disease modelling, drug screening, and studying the functions of…”
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Role of Long Non-Coding RNAs in Human-Induced Pluripotent Stem Cells Derived Megakaryocytes: A p53, HOX Antisense Intergenic RNA Myeloid 1, and miR-125b Interaction Study
Published in The Journal of pharmacology and experimental therapeutics (01-01-2023)“…Megakaryocytes (MKs) are rare polyploid cells found in the bone marrow and produce platelets. Platelets are small cell fragments that are essential during…”
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The first two cell-fate decisions of preimplantation mouse embryo development are not functionally independent
Published in Scientific reports (13-10-2015)“…During mouse preimplantation embryo development, three distinct cell lineages are formed, represented by the differentiating trophectoderm (TE), primitive…”
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