Search Results - "Tham, C S"

ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter by Atkinson, B N, Bell, S C, De Vivo, M, Kowalski, L R, Lechner, S M, Ognyanov, V I, Tham, C S, Tsai, C, Jia, J, Ashton, D, Klitenick, M A

“…High-affinity glycine transport in neurons and glial cells is a primary means of inactivating synaptic glycine. We have synthesized a potent selective…”
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Highly enriched cardiomyocytes from human embryonic stem cells by Xu, X.Q, Zweigerdt, R, Soo, S.Y, Ngoh, Z.X, Tham, S.C, Wang, S.T, Graichen, R, Davidson, B, Colman, A, Sun, W

“…Background Current efforts to direct differentiation of human embryonic stem cells (hESC) into a particular cell lineage usually lead to a heterogeneous cell…”
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Imaging in index finger radial collateral ligament injury: attention to detail really pays by Chotai, N C, Tham, S C, Wansaicheong, G, Tandon, A A

“…Radial collateral ligament of the index finger is a rare ligament to rupture. X-ray is generally normal, except for subtle findings of soft tissue swelling and…”
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IgG4-related disease in a multi-ethnic community: clinical characteristics and association with malignancy by Poo, S X, Tham, C S W, Smith, C, Lee, J, Cairns, T, Galliford, J, Hamdulay, S, Jacyna, M, Levy, J B, McAdoo, S P, Roufosse, C, Wernig, F, Mason, J C, Pusey, C D, Tam, F W K, Tomlinson, J A P

“…Abstract Background Immunoglobulin-G4-related disease (IgG4-RD) is a recently recognized fibro-inflammatory condition that can affect multiple organs. Despite…”
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Decoupling of normal CD40 interleukin-4 immunoglobulin heavy chain switch signal leads to genomic instability in SGH-MM5 and RPMI 8226 multiple myeloma cell lines by HWANG, W. Y. K, GULLO, C. A, SHEN, J, POH, C. K, THAM, S. C, COW, G, AU, M, CHAN, E. W. E, TEOH, G

“…The processes mediating genomic instability and clonal evolution are obscure in multiple myeloma (MM). Acquisition of new chromosomal translocations into the…”
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Dopaminergic regulation of striatal acetylcholine release: importance of D1 and N-methyl-D-aspartate receptors by Damsma, G, Robertson, G S, Tham, C S, Fibiger, H C

“…The dopaminergic regulation of striatal cholinergic activity was studied using in vivo microdialysis to measure interstitial concentrations of acetylcholine…”
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Receptor mechanisms mediating clozapine-induced c-fos expression in the forebrain by Guo, N., Klitenick, M.A., Tham, C.-S., Fibiger, H.C.

“…The atypical antipsychotic clozapine produces distinctly different regional patterns of c-fos expression in rat forebrain than does the prototypical…”
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Receptor mechanisms mediating clozapine-inducedc-fos expression in the forebrain by Guo, N., Klitenick, M.A., Tham, C.-S., Fibiger, H.C.

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An acid phosphatase from Manihot glaziovii as an alternative to alkaline phosphatase for molecular cloning experiments by THAM, S. C, LIM, S. H, YEOH, H. H

“…An acid phosphatase, free of deoxyribonuclease activity, was isolated from Manihot glaziovii leaves. It had a Mr of 78 kDa and was optimally active at pH 4.3…”
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The effects of 2% lignocaine gel on incidence of retching with the use of the laryngeal mask airway by Chan, S T, Tham, C S

“…This randomised, single-blind study investigated the incidence of retching during emergence from general anaesthesia with a laryngeal mask airway in place…”
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Modulating effects of lignocaine on propofol by THAM, C. S, KHOO, S. T

“…Pain is a well known complication of propofol injection. Premixing with lignocaine 0.1 mg.kg-1 and injection into a large forearm vein has been recommended…”
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In vivo comparisons of the effects of quinpirole and the putative presynaptic dopaminergic agonists B-HT 920 and SND 919 on striatal dopamine and acetylcholine release by Robertson, G S, Tham, C S, Wilson, C, Jakubovic, A, Fibiger, H C

“…The extent to which the putative dopamine (DA) autoreceptor agonists B-HT 920 (6-allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5d]azepine dihydrochloride) and…”
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The Putative Atypical Antipsychotic Drug Amperozide Preferentially Increases c-fos Expression in Rat Medial Prefrontal Cortex and Lateral Septum by Nomikos, M.D., Ph.D, George G, Tham, B.Sc, Chui-Se, Fibiger, Ph.D, H.Christian, Svensson, M.D., Ph.D, Torgny H

“…The effects of acute, systemic administration of the putative atypical antipsychotic drug amperozide on c-fos expression in the rat forebrain were studied by…”
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Isolation, characterization and potential application of deoxyribonuclease-free phosphatase from cassava leaves by Tham, S.C, Lim, S.H, Yeoh, H.H

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Growth factor pre‐treatment differentially regulates phosphoinositide turnover downstream of lysophospholipid receptor and metabotropic glutamate receptors in cultured rat cerebrocortical astrocytes by Rao, Tadimeti S., Lariosa‐Willingham, Karen D., Lin, Fen‐Fen, Yu, Naichen, Tham, Chui‐Se, Chun, Jerold, Webb, Michael

“…Reactive gliosis is an aspect of neural plasticity and growth factor (GF) stimulation of astrocytes in vitro is widely regarded as a model system to study…”
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Lesions of the mesotelencephalic dopamine system enhance the effects of selective dopamine D1 and D2 receptor agonists on striatal acetylcholine release by Robertson, G S, Hubert, G W, Tham, C S, Fibiger, H C

“…In vivo microdialysis was used to determine the effects of 6-hydroxydopamine (6-OHDA) lesions of the mesotelencephalic dopamine system on dopamine receptor…”
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Dopamine D1 receptor stimulation increases striatal acetylcholine release in the rat by Damsma, G, Tham, C S, Robertson, G S, Fibiger, H C

“…The effect of selective D1 receptor agonists on acetylcholine (ACh) release in the striatum was investigated using in vivo microdialysis. Administration of the…”
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Inhibition of microglial fatty acid amide hydrolase modulates LPS stimulated release of inflammatory mediators by Tham, Chui-Se, Whitaker, John, Luo, Lin, Webb, Michael

“…Anandamide and other fatty acid amides are metabolised by the enzyme fatty acid amide hydrolase (FAAH), which thereby regulates their endogenous levels. Here…”
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Dopamine depletion attenuates amphetamine-induced increases of cortical acetylcholine release by Day, J C, Tham, C S, Fibiger, H C

“…The extent to which the d-amphetamine (2.0 mg/kg)-induced increase in cortical acetylcholine release is mediated by dopamine and/or noradrenaline was assessed…”
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Cocaine and d-amphetamine increase c-fos expression in the rat cerebellum by Klitenick, M A, Tham, C S, Fibiger, H C

“…Psychostimulant drugs have been reported to increase the expression of some immediate-early genes in the cerebellum. In the present study, immunohistochemical…”
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