Search Results - "Thalmann, George N."

European Association of Urology Guidelines on Muscle-invasive and Metastatic Bladder Cancer: Summary of the 2020 Guidelines by Witjes, J. Alfred, Bruins, Harman Max, Cathomas, Richard, Compérat, Eva M., Cowan, Nigel C., Gakis, Georgios, Hernández, Virginia, Linares Espinós, Estefania, Lorch, Anja, Neuzillet, Yann, Rouanne, Mathieu, Thalmann, George N., Veskimäe, Erik, Ribal, Maria J., van der Heijden, Antoine G.

“…This overview presents the updated European Association of Urology (EAU) guidelines for muscle-invasive and metastatic bladder cancer (MMIBC). To provide…”
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Biology of Bone Metastases in Prostate Cancer by Hensel, Janine, Thalmann, George N

“…Advanced-stage prostate cancer (PCa) patients are often diagnosed with bone metastases. Bone metastases remain incurable and therapies are palliative. PCa…”
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The 2021 Updated European Association of Urology Guidelines on Metastatic Urothelial Carcinoma by Cathomas, Richard, Lorch, Anja, Bruins, Harman M., Compérat, Eva M., Cowan, Nigel C., Efstathiou, Jason A., Fietkau, Rainer, Gakis, Georgios, Hernández, Virginia, Espinós, Estefania Linares, Neuzillet, Yann, Ribal, Maria J., Rouanne, Matthieu, Thalmann, George N., van der Heijden, Antoine G., Veskimäe, Erik, Alfred Witjes, J., Milowsky, Matthew I.

“…Patients with treatment-naïve metastatic urothelial carcinoma are grouped according to platinum eligibility based on clear definitions. In general, first-line…”
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The Role of Cancer-Associated Fibroblasts in Prostate Cancer Tumorigenesis by Bonollo, Francesco, Thalmann, George N, Kruithof-de Julio, Marianna, Karkampouna, Sofia

“…Tumors strongly depend on their surrounding tumor microenvironment (TME) for growth and progression, since stromal elements are required to generate the…”
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Evolution of Urothelial Bladder Cancer in the Context of Molecular Classifications by Minoli, Martina, Kiener, Mirjam, Thalmann, George N, Kruithof-de Julio, Marianna, Seiler, Roland

“…Bladder cancer is a heterogeneous disease that is not depicted by current classification systems. It was originally classified into non-muscle invasive and…”
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Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy by Gakis, Georgios, Black, Peter C, Bochner, Bernard H, Boorjian, Stephen A, Stenzl, Arnulf, Thalmann, George N, Kassouf, Wassim

“…Abstract Context Urothelial carcinoma is considered a pan-urothelial disease. As such, the remnant urothelium in the upper urinary tract and urethra following…”
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Her2 alterations in muscle-invasive bladder cancer: Patient selection beyond protein expression for targeted therapy by Kiss, Bernhard, Wyatt, Alexander W., Douglas, James, Skuginna, Veronika, Mo, Fan, Anderson, Shawn, Rotzer, Diana, Fleischmann, Achim, Genitsch, Vera, Hayashi, Tetsutaro, Neuenschwander, Maja, Buerki, Christine, Davicioni, Elai, Collins, Colin, Thalmann, George N., Black, Peter C., Seiler, Roland

“…Although the introduction of novel targeted agents has improved patient outcomes in several human cancers, no such advance has been achieved in muscle-invasive…”
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Bladder cancer organoids as a functional system to model different disease stages and therapy response by Minoli, Martina, Cantore, Thomas, Hanhart, Daniel, Kiener, Mirjam, Fedrizzi, Tarcisio, La Manna, Federico, Karkampouna, Sofia, Chouvardas, Panagiotis, Genitsch, Vera, Rodriguez-Calero, Antonio, Compérat, Eva, Klima, Irena, Gasperini, Paola, Kiss, Bernhard, Seiler, Roland, Demichelis, Francesca, Thalmann, George N., Kruithof-de Julio, Marianna

“…Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment failure, suggesting that patients could benefit from a more personalized…”
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Bacillus Calmette-Guérin Strain Differences Have an Impact on Clinical Outcome in Bladder Cancer Immunotherapy by Rentsch, Cyrill A, Birkhäuser, Frédéric D, Biot, Claire, Gsponer, Joël R, Bisiaux, Aurélie, Wetterauer, Christian, Lagranderie, Micheline, Marchal, Gilles, Orgeur, Mickael, Bouchier, Christiane, Bachmann, Alexander, Ingersoll, Molly A, Brosch, Roland, Albert, Matthew L, Thalmann, George N

“…Abstract Background Whether the commonly used bacillus Calmette-Guérin (BCG) strains Connaught and Tice confer different treatment responses in…”
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Divergent Biological Response to Neoadjuvant Chemotherapy in Muscle-invasive Bladder Cancer by Seiler, Roland, Gibb, Ewan A, Wang, Natalie Q, Oo, Htoo Zarni, Lam, Hung-Ming, van Kessel, Kim E, Voskuilen, Charlotte S, Winters, Brian, Erho, Nicholas, Takhar, Mandeep M, Douglas, James, Vakar-Lopez, Funda, Crabb, Simon J, van Rhijn, Bas W G, Fransen van de Putte, Elisabeth E, Zwarthoff, Ellen C, Thalmann, George N, Davicioni, Elai, Boormans, Joost L, Dall'Era, Marc, van der Heijden, Michiel S, Wright, Jonathan L, Black, Peter C

“…After cisplatin-based neoadjuvant chemotherapy (NAC), 60% of patients with muscle-invasive bladder cancer (MIBC) still have residual invasive disease at…”
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Prostate Specific Antigen Criteria to Diagnose Failure of Cancer Control following Focal Therapy of Nonmetastatic Prostate Cancer Using High Intensity Focused Ultrasound by Huber, Philipp M, Afzal, Naveed, Arya, Manit, Boxler, Silvan, Dudderidge, Tim, Emberton, Mark, Guillaumier, Stephanie, Hindley, Richard G, Hosking-Jervis, Feargus, Leemann, Lucas, Lewi, Henry, McCartan, Neil, Moore, Caroline M, Nigam, Raj, Odgen, Chris, Persad, Raj, Thalmann, George N, Virdi, Jaspal, Winkler, Mathias, Ahmed, Hashim U

“…We determined whether prostate specific antigen criteria after focal high intensity focused ultrasound to treat prostate cancer could diagnose treatment…”
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High Aldehyde Dehydrogenase Activity Identifies Tumor-Initiating and Metastasis-Initiating Cells in Human Prostate Cancer by VAN DEN HOOGEN, Christel, VAN DER HORST, Geertje, PELGER, Rob C. M, VAN DER PLUIJM, Gabri, CHEUNG, Henry, BUIJS, Jeroen T, LIPPITT, Jenny M, GUZMAN-RAMIREZ, Natalia, HAMDY, Freddie C, EATON, Colby L, THALMANN, George N, CECCHINI, Marco G

“…Metastatic progression of advanced prostate cancer is a major clinical problem. Identifying the cell(s) of origin in prostate cancer and its distant metastases…”
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miR-221-5p regulates proliferation and migration in human prostate cancer cells and reduces tumor growth in vivo by Kiener, Mirjam, Chen, Lanpeng, Krebs, Markus, Grosjean, Joël, Klima, Irena, Kalogirou, Charis, Riedmiller, Hubertus, Kneitz, Burkhard, Thalmann, George N, Snaar-Jagalska, Ewa, Spahn, Martin, Kruithof-de Julio, Marianna, Zoni, Eugenio

“…Despite latest advances in prostate cancer (PCa) therapy, PCa remains the third-leading cause of cancer-related death in European men. Dysregulation of…”
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Acute Toxicity and Quality of Life After Dose-Intensified Salvage Radiation Therapy for Biochemically Recurrent Prostate Cancer After Prostatectomy: First Results of the Randomized Trial SAKK 09/10 by Ghadjar, Pirus, Hayoz, Stefanie, Bernhard, Jürg, Zwahlen, Daniel R, Hölscher, Tobias, Gut, Philipp, Guckenberger, Matthias, Hildebrandt, Guido, Müller, Arndt-Christian, Plasswilm, Ludwig, Papachristofilou, Alexandros, Stalder, Lukas, Biaggi-Rudolf, Christine, Sumila, Marcin, Kranzbühler, Helmut, Najafi, Yousef, Ost, Piet, Azinwi, Ngwa C, Reuter, Christiane, Bodis, Stephan, Kaouthar, Khanfir, Wust, Peter, Thalmann, George N, Aebersold, Daniel M

“…Patients with biochemical failure (BF) after radical prostatectomy may benefit from dose-intensified salvage radiation therapy (SRT) of the prostate bed. We…”
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Preoperative plasma fatty acid metabolites inform risk of prostate cancer progression and may be used for personalized patient stratification by Zoni, Eugenio, Minoli, Martina, Bovet, Cédric, Wehrhan, Anne, Piscuoglio, Salvatore, Ng, Charlotte K Y, Gray, Peter C, Spahn, Martin, Thalmann, George N, Kruithof-de Julio, Marianna

“…Little is known about the relationship between the metabolite profile of plasma from pre-operative prostate cancer (PCa) patients and the risk of PCa…”
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Radical Cystectomy for Bladder Cancer Today—A Homogeneous Series Without Neoadjuvant Therapy by MADERSBACHER, Stephan, HOCHREITER, Werner, BURKHARD, Fiona, THALMANN, George N, DANUSER, Hansjörg, MARKWALDER, Regula, STUDER, Urs E

“…To investigate the effect of pelvic lymph node dissection and radical cystectomy for transitional cell cancer of the bladder on recurrence-free and overall…”
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Dual-mTOR Inhibitor Rapalink-1 Reduces Prostate Cancer Patient-Derived Xenograft Growth and Alters Tumor Heterogeneity by La Manna, Federico, De Menna, Marta, Patel, Nikhil, Karkampouna, Sofia, De Filippo, Maria Rosaria, Klima, Irena, Kloen, Peter, Beimers, Lijkele, Thalmann, George N, Pelger, Rob C M, Jacinto, Estela, Kruithof-de Julio, Marianna

“…Bone metastasis is the leading cause of prostate cancer (PCa) mortality, frequently marking the progression to castration-resistant PCa. Dysregulation of the…”
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The molecular signature of the stroma response in prostate cancer-induced osteoblastic bone metastasis highlights expansion of hematopoietic and prostate epithelial stem cell niches by Özdemir, Berna C, Hensel, Janine, Secondini, Chiara, Wetterwald, Antoinette, Schwaninger, Ruth, Fleischmann, Achim, Raffelsberger, Wolfgang, Poch, Olivier, Delorenzi, Mauro, Temanni, Ramzi, Mills, Ian G, van der Pluijm, Gabri, Thalmann, George N, Cecchini, Marco G

“…The reciprocal interaction between cancer cells and the tissue-specific stroma is critical for primary and metastatic tumor growth progression. Prostate cancer…”
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Epidural analgesia during open radical prostatectomy does not improve long-term cancer-related outcome: a retrospective study in patients with advanced prostate cancer by Wuethrich, Patrick Y, Thalmann, George N, Studer, Urs E, Burkhard, Fiona C

“…A beneficial effect of regional anesthesia on cancer related outcome in various solid tumors has been proposed. The data on prostate cancer is conflicting and…”
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A New Multimodality Technique Accurately Maps the Primary Lymphatic Landing Sites of the Bladder by Roth, Beat, Wissmeyer, Michael P, Zehnder, Pascal, Birkhäuser, Frédéric D, Thalmann, George N, Krause, Thomas M, Studer, Urs E

“…Abstract Background Pathoanatomic studies have failed to map accurately the primary lymphatic landing sites of the urinary bladder. Objective To use…”
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