Search Results - "Thall, A."

A PHASE I STUDY OF UTOMILUMAB (PF‐05082566), A 4‐1BB/CD137 AGONIST, IN COMBINATION WITH RITUXIMAB IN PATIENTS WITH CD20+ NON‐HODGKIN'S LYMPHOMA by Gopal, A., Levy, R., Houot, R., Patel, S., Hatake, K., Popplewell, L., Chen, Y., Davis, C., Huang, B., Cesari, R., Thall, A., Woolfson, A., Bartlett, N.

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BLOCKADE OF THE PD‐1 CHECKPOINT WITH ANTI–PD‐L1 ANTIBODY AVELUMAB IS SUFFICIENT FOR CLINICAL ACTIVITY IN RELAPSED/REFRACTORY CLASSICAL HODGKIN LYMPHOMA (CHL) by Chen, R., Gibb, A.L., Collins, G.P., Popat, R., El‐Sharkawi, D., Burton, C., Lewis, D., Miall, F.M., Forgie, A., Compagnoni, A., Andreola, G., Brar, S., Thall, A., Woolfson, A., Radford, J.

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Multiscale deformable model segmentation and statistical shape analysis using medial descriptions by Joshi, S., Pizer, S., Fletcher, P.T., Yushkevich, P., Thall, A., Marron, J.S.

“…This paper presents a multiscale framework based on a medial representation for the segmentation and shape characterization of anatomical objects in medical…”
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High-dose porcine hematopoietic cell transplantation combined with CD40 ligand blockade in baboons prevents an induced anti-pig humoral response by BÜHLER, L, AWWAD, M, DOWN, J. D, SYKES, M, ANDREWS, D, SACKSTEIN, R, WHITE-SCHARF, M. E, SACHS, D. H, COOPER, D. K. C, BASKER, M, GOJO, S, WATTS, A, TRETER, S, NASH, K, ORAVEC, G, CHANG, Q, THALL, A

“…In pig-to-primate organ transplantation, hyperacute rejection can be prevented, but the organ is rejected within days by acute vascular rejection, in which…”
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A phase I dose-escalation and pharmacokinetic study of sunitinib in combination with pemetrexed in patients with advanced solid malignancies, with an expanded cohort in non-small cell lung cancer by Chow, L. Q. M., Blais, N., Jonker, D. J., Laurie, S. A., Diab, S. G., Canil, C., McWilliam, M., Thall, A., Ruiz-Garcia, A., Zhang, K., Tye, L., Chao, R. C., Camidge, D. R.

“…Purpose The primary objective of this phase I dose-escalation study was to identify the maximum tolerated dose (MTD) of sunitinib plus pemetrexed in patients…”
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Intraventricular and intravenous treatment of a patient with refractory primary CNS lymphoma using rituximab by PELS, H, SCHULZ, H, MANZKE, O, HOM, E, THALL, A, ENGERT, A

“…The treatment of primary central nervous system lymphoma (PCNSL) with chemo- and radiotherapy is efficient in terms of tumor response. However, time to tumor…”
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Oocyte Gal alpha 1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse by Thall, A D, Malý, P, Lowe, J B

“…The Gal alpha 1-->3Gal structure is displayed on the zona pellucida glycoprotein ZP3 on murine oocytes. This trisaccharide has been implicated in sperm-zona…”
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The α(1,3)fucosyltransferases FucT-IV and FucT-VII Exert Collaborative Control over Selectin-Dependent Leukocyte Recruitment and Lymphocyte Homing by Homeister, Jonathon W, Thall, Aron D, Petryniak, Bronia, Malý, Petr, Rogers, Clare E, Smith, Peter L, Kelly, Robert J, Gersten, Kevin M, Askari, Sanaz W, Cheng, Guiying, Smithson, Glennda, Marks, Rory M, Misra, Anup K, Hindsgaul, Ole, von Andrian, Ulrich H, Lowe, John B

“…E-, P-, and L-selectin counterreceptor activities, leukocyte trafficking, and lymphocyte homing are controlled prominently but incompletely by…”
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One Percent of Human Circulating B Lymphocytes Are Capable of Producing the Natural Anti-Gal Antibody by Galili, Uri, Anaraki, Fari, Thall, Aron, Hill-Black, Caprice, Radic, Marko

“…The natural anti-Gal antibody constitutes 1 % of circulating IgG in humans and interacts specifically with the carbohydrate epitope Galαl -3Galβ1 -4GlcNAc-R…”
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The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis by Malý, Petr, Thall, Aron D, Petryniak, Bronislawa, Rogers, Clare E, Smith, Peter L, Marks, Rory M, Kelly, Robert J, Gersten, Kevin M, Cheng, Guiying, Saunders, Thomas L, Camper, Sally A, Camphausen, Ray T, Sullivan, Francis X, Isogai, Yukihiro, Hindsgaul, Ole, von Andrian, Ulrich H, Lowe, John B

“…α(1,3)Fucosylated oligosaccharides represent components of leukocyte counterreceptors for E- and P-selectins and of L-selectin ligands expressed by lymph node…”
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Mac-1-negative B-1b phenotype of natural antibody-producing cells, including those responding to Gal alpha 1,3Gal epitopes in alpha 1,3-galactosyltransferase-deficient mice by Ohdan, H, Swenson, K G, Kruger Gray, H S, Yang, Y G, Xu, Y, Thall, A D, Sykes, M

“…Human natural Abs against Galalpha1-3Galbeta1-4GlcNAc (Gal) epitopes are a major barrier to xenotransplantation. Studies in this report, which use combined…”
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A murine model of antibody-mediated hyperacute rejection by galactose-α(1,3)galactose antibodies in Gal o/o mice by MCKENZIE, I. F. C, YU QIN LI, PATTON, K, THALL, A. D, SANDRIN, M. S

“…In pig-to-primate/human xenografts, hyperacute rejection of primarily vascularized organs usually occurs in 10-60 min and is due to the reaction of the…”
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Importance of the GAL α1-3 GAL antigen in discordant islet xenotransplantation: Immunosuppression, which inhibits porcine islet xenograft rejection in ordinary mice, is equally effective in GAL-knockout mice by WENNBERG, L, SONG, Z, BENNET, W, SANDBERG, J. O, SUNDBERG, B, THALL, A, KORSGREN, O

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CD40-CD154 pathway blockade requires host macrophages to induce humoral unresponsiveness to pig hematopoietic cells in baboons by BÜHLER, L, ALWAYN, I. P. J, BASKER, M, ORAVEC, G, THALL, A, WHITE-SCHARF, M. E, SACHS, D. H, AWWAD, M, COOPER, D. K. C

“…The effect of CD154 blockade and macrophage depletion or inhibition on baboon humoral and cellular immune responses to pig antigens was studied in a…”
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Generation of alpha 1,3galactosyltransferase deficient mice by Thall, A D

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1976TiP A multi-national study of treatment resistance following anti-cancer therapy (TRANSLATE) by Helissey, C., Di Simone, C., Nasurdi, C., Martini, J-F., Thall, A., Cossons, N., Ho, S.

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9155 Sunitinib combined with pemetrexed and cisplatin in patients with advanced solid malignancies: phase I dose escalation study by Blais, N, Camidge, D.R, Jonker, D.J, Soulières, D, Doebele, R.C, Ruiz-Garcia, A, Thall, A, Chao, R, Eckhardt, S.G, Chow, L.Q

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Elimination of Porcine Hemopoietic Cells by Macrophages in Mice by Abe, Masahiro, Cheng, Jane, Qi, Jin, Glaser, Roseann M, Thall, Aron D, Sykes, Megan, Yang, Yong-Guang

“…The difficulty in achieving donor hemopoietic engraftment across highly disparate xenogeneic species barriers poses a major obstacle to exploring xenograft…”
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P-selectin Glycoprotein Ligand-1 and E-selectin Ligand-1 Are Differentially Modified by Fucosyltransferases Fuc-TIV and Fuc-TVII in Mouse Neutrophils by Huang, Min-Chuan, Zöllner, Olaf, Moll, Thomas, Maly, Petr, Thall, Aron D., Lowe, John B., Vestweber, D.

“…P-selectin glycoprotein ligand-1 (PSGL-1) and E-selectin ligand-1 (ESL-1) are the two major selectin ligands on mouse neutrophils. Transfection experiments…”
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Inhibition of human anti-pig T cell response by anti-CD2, anti-CD40L, and CTLA4-Ig: a comparative study by Xu, Y, Ryan, D, Wu, C, Bazin, H, Latinne, D, White-Scharf, M.E, Thall, A.D

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