Search Results - "Thalassemia reports"

Thalassemia: Pathophysiology, Diagnosis, and Advances in Treatment by Sadiq, Idris Zubairu, Abubakar, Fatima Sadiq, Usman, Hauwa Salisu, Abdullahi, Aliyu Dantani, Ibrahim, Bashiru, Kastayal, Babangida Sanusi, Ibrahim, Maryam, Hassan, Hassan Aliyu

“…Thalassemia represents a diverse group of inherited hematological disorders characterized by defective globin chain synthesis, leading to chronic anemia and…”
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β-Thalassemia in Bangladesh: Current Status and Future Perspectives by Mitro, Arnob, Hossain, Didar, Rahman, Md Muhibur, Dam, Beauty, Hosen, Mohammad Jakir

“…β-thalassemia, a life-threatening inheritable hemoglobin disorder caused by mutations in the HBB gene, poses a significant public health challenge in the…”
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The Effect of Resveratrol on Gamma Globin Gene Expression in Patients with Beta Thalassemia: The Role of Adaptation to Cellular Stress by Jalali, Hossein, Mahdavi, Mohammad Reza, Kosaryan, Mehrnoush, Najafi, Ahmad, Aliasgharian, Aily, Salehifar, Ebrahim

“…HbF induction is an appropriate strategy to ameliorate the severity of β-thalassemia symptoms. Hydroxyurea (HU) is the most common chemical agent introduced as…”
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Sociodemographic Determinants of Adherence and Treatment Efficacy in Paediatric Thalassemia Patients from Sarbaz-Rask, Iran by Atousa Babamohammadi, QiYuee Wang, Elham Mohajeri, Saeid Esmaeilian

“…Background: The effective management of iron overload in transfusion-dependent thalassemia (TDT) requires adherence to iron chelation therapy (ICT). However,…”
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Cardiovascular Complications in β-Thalassemia: Getting to the Heart of It by Akiki, Nathalie, Hodroj, Mohammad H., Bou-Fakhredin, Rayan, Matli, Kamal, Taher, Ali T.

“…Beta thalassemia is an inherited disorder resulting in abnormal or decreased production of hemoglobin, leading to hemolysis and chronic anemia. The long-term…”
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Unveiling Extramedullary Hematopoiesis: A Case Report Highlighting the Causes, Symptoms, and Management Strategies by Manganas, Konstantinos, Xydaki, Aikaterini, Kotsiafti, Angeliki, Papakonstantinou, Olympia, Delicou, Sophia

“…Extramedullary hematopoiesis (EMH) serves as a compensatory mechanism in chronic hemolytic anemias, such as thalassemia, and can result in spinal cord…”
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Premarital Counseling on the Alpha Thalassemia Allele HBA2:c.94A>G by Alderei, Latifa, Alshkeili, Nouf, Alnaqbi, Dana, Shehab, Omar Abdulla, Vijayan, Ranjit, Souid, Abdul-Kader

“…The mutation HBA2:c.*94A>G (AATAAA>AATAAG; rs63751269) is a 3′-UTR (3 prime untranslated region) single-nucleotide substitution in the polyadenylation (PA)…”
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Psychological Burden among Pediatric Thalassemia Major Patients in Indonesia: A Review by Sari, Teny Tjitra, Rahmartani, Ludi Dhyani, Wirahmadi, Angga, Selene, Nathasha Brigitta, Iskandar, Stephen Diah, Wahidiyat, Pustika Amalia

“…Thalassemia a common hereditary blood disorder resulting in anemia. It is an important public health problem, with a high prevalence in Southeast Asia and…”
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Infection and Potential Challenge of Childhood Mortality in Sickle Cell Disease: A Comprehensive Review of the Literature from a Global Perspective by Sahu, Tarun, Pande, Babita, Verma, Henu Kumar, Bhaskar, L V K S, Sinha, Meenakshi, Sinha, Ramanjan, Rao, Pasupuleti Visweswara

“…Sickle cell disease (SCD) is a complex genetic disorder associated with multiple clinical manifestations, including increased susceptibility to bacterial and…”
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Association between Glomerular Filtration Rate and β-Thalassemia Major: A Systematic Review and Meta-Analysis by Khandker, Shahad Saif, Jannat, Nurani, Sarkar, Deepannita, Pranto, Alif Hasan, Hoque, Ismoth Ara, Zaman, Jemema, Uddin, Md. Nizam, Suez, Ehsan

“…Thalassemia is one of the most prevalent genetic disorders worldwide and has previously been found to have an association with several physiological and organ…”
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Alpha-Thalassemia: Diversity of Clinical Phenotypes and Update on the Treatment by Songdej, Duantida, Fucharoen, Suthat

“…One of the more common single-gene disorders worldwide is α-thalassemia, carriers of which are found at variable frequencies (>1%) across all tropical and…”
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Causes of Hospitalizations in Pediatric Patients with Thalassemia under the National Health Coverage Scheme in Thailand by Charoenkwan, Pimlak, Komvilaisak, Patcharee, Thepsuthummarat, Kaewjai, Seksarn, Panya, Torcharus, Kitti

“…Thalassemia is a hereditary hemolytic anemia that is prevalent in Southeast Asia. The primary treatment for severe thalassemia involves red cell transfusion,…”
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A Case Report of Hyperhemolytic Syndrome in Sickle Cell Disease, with a Special Focus on Avoiding the Use of Transfusions by Obajed Al-Ali, Omar, Pfliegler, György, Magyari, Ferenc, Borics, Fanni, Pinczés, László Imre, Illés, Árpád, Brúgós, Boglárka

“…In patients with sickle cell disease (SCD), transfusions pose risks like delayed hemolytic transfusion reaction (DHTR) and hyperhemolytic syndrome (HHS). We…”
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Challenges of Iron Chelation in Thalassemic Children by Adramerina, Alkistis, Economou, Marina

“…Thalassemia treatment still relies on supportive care, mainly including blood transfusion and iron chelation therapy. Iron chelation is considered the main…”
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Understanding the Intricacies of Iron Overload Associated with β-Thalassemia: A Comprehensive Review by Basu, Subhangi, Rahaman, Motiur, Dolai, Tuphan Kanti, Shukla, Praphulla Chandra, Chakravorty, Nishant

“…β-thalassemia, a congenital genetic hematological disorder characterized by the decrease or absence of β-globin chains, leads to a decrease in levels of…”
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β Thalassemia Mutation Flow in Indonesia: A Migration Perspective by Rujito, Lantip, Maritska, Ziske, Sofro, Abdul Salam

“…Indonesia is a large island country with a wide variety of ethnic groups. As part of the thalassemia country belt, Indonesia has alleles that are as…”
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Amlodipine Therapy in β-Thalassemia Patients: A Systematic Review and Meta-Analysis on Ferritin Levels and Liver MRI T2 by Aliasgharian, Aily, Karami, Hossein, Zahedi, Mohammad, Jahanshahi, Reza, Bakhtiari-Dovvombaygi, Hossein, Nasirzadeh, Amirreza, Naderisorki, Mohammad, Kosaryan, Mehrnoush, Salehifar, Ebrahim, Ghazaiean, Mobin, Bitaraf, Saeid, Darvishi-Khezri, Hadi

“…Background and aim: We conducted a review to determine the efficacy of amlodipine alongside iron chelators on serum ferritin levels and liver T2-weighted…”
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Association of Bone Disorder and Gene Polymorphism of PPAR-γ Pro12 Ala in Egyptian Children with β-Thalassemia by Hamied, Ahmed M. Abdel, Ahmed, Heba Mostafa, Eldahshan, Dina H., Morgan, Dalia S., Meged, Abdel Meged A. Abdel, Elgendy, Marwa O., Imam, Mohamed S., Alotaibi, Turki A. H., Alotaibi, Majed M. S., Alotaibi, Manal T. N., Alshalan, Sarah S. S., Elgendy, Sara O.

“…β-thalassemia is a genetic disorder affecting chromosome 16, inherited from one or both parents. In spite of the improved treatment of the hematological…”
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CRISPR Gene Therapy: A Promising One-Time Therapeutic Approach for Transfusion-Dependent β-Thalassemia—CRISPR-Cas9 Gene Editing for β-Thalassemia by Gamage, Udani, Warnakulasuriya, Kesari, Hansika, Sonali, Silva, Gayathri N.

“…β-Thalassemia is an inherited hematological disorder that results from genetic changes in the β-globin gene, leading to the reduced or absent synthesis of…”
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New-Generation Ektacytometry Study of Red Blood Cells in Different Hemoglobinopathies and Thalassemia by Krishnevskaya, Elena, Molero, Marta, Ancochea, Águeda, Hernández, Ines, Vives-Corrons, Joan-Lluis

“…Next-generation ektacytometry provided by the osmoscan module of the Laser Optical Rotational Red Cell Analyser (LoRRca) MaxSis is, so far, one of the best…”
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