Search Results - "Thakker, Suhani"
-
1
Co-infections and Pathogenesis of KSHV-Associated Malignancies
Published in Frontiers in microbiology (15-02-2016)“…Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpes virus 8 (HHV-8) is one of the several carcinogenic viruses that infect humans. KSHV…”
Get full text
Journal Article -
2
Transcriptome analysis of Kaposi's sarcoma-associated herpesvirus during de novo primary infection of human B and endothelial cells
Published in Journal of virology (01-03-2015)“…Kaposi's sarcoma-associated herpesvirus (KSHV) infects many target cells (e.g., endothelial, epithelial, and B cells, keratinocytes, and monocytes) to…”
Get full text
Journal Article -
3
KSHV encoded LANA recruits Nucleosome Assembly Protein NAP1L1 for regulating viral DNA replication and transcription
Published in Scientific reports (07-09-2016)“…The establishment of latency is an essential for lifelong persistence and pathogenesis of Kaposi’s sarcoma-associated herpesvirus (KSHV). Latency-associated…”
Get full text
Journal Article -
4
Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Inhibits Major Histocompatibility Complex Class II Expression by Disrupting Enhanceosome Assembly through Binding with the Regulatory Factor X Complex
Published in Journal of virology (01-05-2015)“…Major histocompatibility complex class II (MHC-II) molecules play a central role in adaptive antiviral immunity by presenting viral peptides to CD4(+) T cells…”
Get full text
Journal Article -
5
Phosphonoacetate Modifications Enhance the Stability and Editing Yields of Guide RNAs for Cas9 Editors
Published in Biochemistry (Easton) (19-12-2023)“…CRISPR gene editing and control systems continue to emerge and inspire novel research and clinical applications. Advances in CRISPR performance such as…”
Get full text
Journal Article -
6
Abstract 2584: Exosome molecular reference standards (Exo-Ref) generated from CRISPR/Cas9 engineered cell Lines for oncology diagnostic applications
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Introduction: Exosomes (commonly known as extracellular vesicles) have generated tremendous interest for the therapeutic and diagnostic applications for…”
Get full text
Journal Article -
7
KSHV LANA upregulates the expression of epidermal growth factor like domain 7 to promote angiogenesis
Published in Oncotarget (02-01-2018)“…Kaposi's sarcoma (KS) is a highly-vascularized tumor characterized by inflammation and extensive neo-angiogenesis. The KS tumor microenvironment is rich in…”
Get full text
Journal Article -
8
Dynamics of KSHV gene expression during de novo infection and the role of LANA in immune modulation
Published 01-01-2015“…Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic human herpes virus that has been linked to the development of multiple malignancies including…”
Get full text
Dissertation -
9
Dynamics of KSHV gene expression during de novo infection and the role of LANA in immune modulation
Get full text
Dissertation