Search Results - "Thakare, Vishnu N"
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Protocatechuic acid attenuates chronic unpredictable mild stress induced-behavioral and biochemical alterations in mice
Published in European journal of pharmacology (05-05-2021)“…Amelioration of oxidative stress via promoting the endogenous antioxidant system and enhancement of monoamines in brain were the important underlying…”
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2
Design, synthesis, characterization and anti-inflammatory evaluation of novel pyrazole amalgamated flavones
Published in Bioorganic & medicinal chemistry letters (01-03-2013)“…A series of novel pyrazole amalgamated flavones have been designed, synthesized and evaluated for their anti-inflammatory potential. A series of novel pyrazole…”
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3
Potential targets for the development of novel antidepressants: future perspectives
Published in CNS & neurological disorders drug targets (01-01-2015)“…Depression is an affective disorder characterized by hallucination, delusion and increased social risk and is estimated to affect approximately 20 % of the…”
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4
Potential antidepressant-like activity of silymarin in the acute restraint stress in mice: Modulation of corticosterone and oxidative stress response in cerebral cortex and hippocampus
Published in Pharmacological reports (01-10-2016)“…Silymarin is a polyphenolic flavanoid of Silybum marianum, elicited neuroprotection and antidepressant like activity in stressed model. It was found to…”
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5
Attenuation of acute restraint stress-induced depressive like behavior and hippocampal alterations with protocatechuic acid treatment in mice
Published in Metabolic brain disease (01-04-2017)“…Protocatechuic acid ethyl ester (PCA), a phenolic compound, exhibits neuroprotective effects through improving endogenous antioxidant enzymatic and nonezymatic…”
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6
Therapeutic potential of silymarin in chronic unpredictable mild stress induced depressive-like behavior in mice
Published in Journal of psychopharmacology (Oxford) (01-02-2018)“…Silymarin, a plant-derived polyphenolic flavonoid of Silybum marianum, elicited significant antidepressant-like activity in an acute restraint stress model of…”
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7
Protective effect of curcumin on experimentally induced inflammation, hepatotoxicity and cardiotoxicity in rats: Evidence of its antioxidant property
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01-07-2011)“…The present study investigates the protective effects of curcumin on experimentally induced inflammation, hepatotoxicity, and cardiotoxicity using various…”
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8
Amelioration of cognitive, motor and endogenous defense functions with silymarin, piracetam and protocatechuic acid in the cerebral global ischemic rat model
Published in Life sciences (1973) (19-07-2013)“…The neuroprotective activities of silymarin, piracetam and protocatechuic acid ethyl ester (PCA) on cerebral global ischemic/reperfusion were evaluated in a…”
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9
Protocatechuic acid attenuate depressive-like behavior in olfactory bulbectomized rat model: behavioral and neurobiochemical investigations
Published in Metabolic brain disease (01-06-2019)“…The main objective of the present study is to investigate potential effects of PCA in OBX induced depressive-like behavior in rat model. PCA was administered…”
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10
Therapeutic potential of curcumin in experimentally induced allergic rhinitis in guinea pigs
Published in International immunopharmacology (01-09-2013)“…In the present experiments, the possible role of curcumin in ovalbumin induced allergic rhinitis in guinea pig model was investigated. Various allergic…”
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11
Silymarin improves the behavioural, biochemical and histoarchitecture alterations in focal ischemic rats: A comparative evaluation with piracetam and protocatachuic acid
Published in Pharmacology, biochemistry and behavior (01-08-2012)“…Comparative neuroprotective potential of silymarin, piracetam and protocatechuic acid ethyl ester (PCA) was evaluated in focal ischemic rats. Various…”
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12
Design, synthesis, characterization and biological evaluation of novel pyrazole integrated benzophenones
Published in Bioorganic & medicinal chemistry letters (01-02-2013)“…A series of novel pyrazole integrated benzophenones have been designed, synthesized and evaluated for their in vitro and in vivo anti-inflammatory activity and…”
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13
Some molecular targets for antihyperlipidemic drug research
Published in European journal of medicinal chemistry (06-10-2014)“…High levels of cholesterol and other lipid constituents are major risk factors in the development of atherosclerosis as well as diseases and disorders…”
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14
Silymarin ameliorates experimentally induced depressive like behavior in rats: Involvement of hippocampal BDNF signaling, inflammatory cytokines and oxidative stress response
Published in Physiology & behavior (01-10-2017)“…Silymarin is a polyphenolic flavonoid of Silybum marianum, exhibited neuroprotection and antidepressant like activity in acute restraint stressed mice. The…”
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15
Ameliorative effects of Tricholepis glaberrima in experimentally induced hepatic damage in rats: Modulation of cytokines functions
Published in Journal of ethnopharmacology (03-02-2015)“…Tricholepis glaberrima belonging to family Asteraceae is popularly known as “Brahmadandi” in Indian system of medicine and is claimed to be effective in the…”
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16
Design, synthesis, characterization and in vitro and in vivo anti-inflammatory evaluation of novel pyrazole-based chalcones
Published in Journal of enzyme inhibition and medicinal chemistry (01-02-2015)“…Abstract A series of novel pyrazole-based chalcones have been designed, synthesized from 1-methyl-5-(2,4,6-trimethoxyphenyl)-1H-pyrazole (6). The structures of…”
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17
Ameliorative effect of Luffa acutangula Roxb. on doxorubicin induced cardiac and nephrotoxicity in mice
Published in Indian journal of experimental biology (01-02-2013)“…The present study reports protective effect of hydro-alcoholic extract of Luffa acutangula (HAELA) on doxorubicin (DXR) induced cardio and nephrotoxicity in…”
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18
Preparation and Pharmacological Evaluation of Novel Orally Active Ester Prodrugs of Ketoprofen with Non-Ulcerogenic Property
Published in Chemical biology & drug design (01-06-2016)“…This study investigates anti‐inflammatory activity with improved pharmacokinetic and non‐ulcerogenic properties of various novel synthesized prodrugs of…”
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19
Hepatoprotective activity of Luffa acutangula against CCl4 and rifampicin induced liver toxicity in rats: a biochemical and histopathological evaluation
Published in Indian journal of experimental biology (01-08-2010)“…Hepatoprotective activity of hydroalcoholic extract of Luffa acutangula (HAELA) against carbon tetrachloride (CCl4) and rifampicin-induced hepatotoxicity in…”
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20
Stem bark extraction of Ficus bengalensis Linn for anti-inflammatory and analgesic activity in animal models
Published in Indian journal of experimental biology (01-01-2010)“…In the present study, anti-inflammatory and analgesic effect of aqueous extract of Ficus bengalensis (AEFB) and methanolic extract of F. bengalensis (MEFB) was…”
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