Search Results - "Thörngren, John‐Olof"

Re‐evaluation of combined ((ES/EG)/(TS/TG)) ratio as a marker of testosterone intake in men by Schulze, Jenny, Pettersson‐Bohlin, Kim, Thörngren, John‐Olof, Ekström, Lena

“…To detect doping with pseudo‐endogenous anabolic steroids in sports, a urinary steroid profile with glucuronidated plus unconjugated androgens is used. In…”
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Digit Ratio (2D:4D) and Physical Performance in Female Olympic Athletes by Eklund, Emma, Ekström, Lena, Thörngren, John-Olof, Ericsson, Magnus, Berglund, Bo, Hirschberg, Angelica Lindén

“…Background: The second to fourth digit ratio (2D:4D ratio) is suggested to be a negative correlate of prenatal testosterone. Little is known about the role of…”
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A high-throughput multicomponent screening method for diuretics, masking agents, central nervous system (CNS) stimulants and opiates in human urine by UPLC-MS/MS by Thörngren, John-Olof, Östervall, Fredrik, Garle, Mats

“…A simple and rapid multicomponent screening method of 130 substances for direct injections of urine samples has been developed. The fully automated method…”
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Urinary steroid profile in females – the impact of menstrual cycle and emergency contraceptives by Mullen, Jenny E., Thörngren, John‐Olof, Schulze, Jenny J., Ericsson, Magnus, Gårevik, Nina, Lehtihet, Mikael, Ekström, Lena

“…Today's doping tests involving longitudinal monitoring of steroid profiles are difficult in women. Women have more complex hormonal fluctuations than men and…”
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Androgen Sulfation in Healthy UDP-Glucuronosyl Transferase 2B17 Enzyme-Deficient Men by Schulze, Jenny J, Thörngren, John-Olof, Garle, Mats, Ekström, Lena, Rane, Anders

“…Context: The conspicuous interindividual differences in metabolism and urinary excretion of testosterone and its metabolites make it challenging to reveal…”
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Testosterone challenge and androgen receptor activity in relation to UGT2B17 genotypes by Ekström, Lena, Cevenini, Luca, Michelini, Elisa, Schulze, Jenny, Thörngren, John-Olof, Belanger, Alain, Guillemette, Chantal, Garle, Mats, Roda, Aldo, Rane, Anders

“…Background We investigated the androgen receptor (AR) bioluminescense response in serum and urine before and after testosterone challenge in different…”
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Pregnancy-Induced Perturbation of Urinary Androgenic Steroid Disposition by Gadot, Yifat, Thörngren, John-Olof, Eklund, Emma, Ekström, Lena, Rane, Anders

“…Abstract Objective To investigate the excretion and conjugation profile of testosterone (T), Epitestosterone (EpiT), and other androgen metabolites in…”
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SULT2A1 Gene Copy Number Variation is Associated with Urinary Excretion Rate of Steroid Sulfates by Schulze, Jenny, Johansson, Maria, Thörngren, John-Olof, Garle, Mats, Rane, Anders, Ekström, Lena

“…Human cytosolic sulfotransferases (SULT) 2A1 is the main enzyme involved in the sulfate conjugation of dehydroepiandrosterone, a weak androgen, and the main…”
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Non-steroidal anti-inflammatory drugs do not influence the urinary testosterone/epitestosterone glucuronide ratio by Lundmark, Jonas, Gårevik, Nina, Thörngren, John-Olof, Garle, Mats, Ekström, Lena, Rane, Anders, Schulze, Jenny J

“…The UDP Glucuronosyl Transferase (UGT) enzymes are important in the pharmacokinetics, and conjugation, of a variety of drugs including non-steroidal…”
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Detection of the free acid of bimatoprost in aqueous humor samples from human eyes treated with bimatoprost before cataract surgery by Camras, Carl B, Toris, Carol B, Sjoquist, Birgitta, Milleson, Monica, Thorngren, John-Olof, Hejkal, Thomas W, Patel, Nehal, Barnett, Edward M, Smolyak, Regina, Hasan, S Fareed, Hellman, Courtney, Meza, Jane L, Wax, Martin B, Stjernschantz, Johan

“…To determine whether bimatoprost is hydrolyzed to its free acid after topical application in humans in vivo. Prospective, masked, and vehicle controlled…”
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A high-throughput multicomponent screening method for diuretics, masking agents, central nervous system (CNS) stimulants and opiates in human urine by UPLC-MS/MS: Sports Doping Explored by THÖRNGREN, John-Olof, OSTERVALL, Fredrik, GARLE, Mats

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Testosterone challenge and androgen receptor activity in relation to UGT 2B17 genotypes by Ekström, Lena, Cevenini, Luca, Michelini, Elisa, Schulze, Jenny, Thörngren, John‐Olof, Belanger, Alain, Guillemette, Chantal, Garle, Mats, Roda, Aldo, Rane, Anders

“…Abstract Background We investigated the androgen receptor ( AR ) bioluminescense response in serum and urine before and after testosterone challenge in…”
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Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study by Kolmert, Johan, Gómez, Cristina, Balgoma, David, Sjödin, Marcus, Bood, Johan, Konradsen, Jon R, Ericsson, Magnus, Thörngren, John-Olof, James, Anna, Mikus, Maria, Sousa, Ana R, Riley, John H, Bates, Stewart, Bakke, Per S, Pandis, Ioannis, Caruso, Massimo, Chanez, Pascal, Fowler, Stephen J, Geiser, Thomas, Howarth, Peter, Horváth, Ildikó, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Behndig, Annelie, Shaw, Dominick E, Knowles, Richard G, J Holweg, Cécile T, Wheelock, Åsa M, Dahlén, Barbro, Nordlund, Björn, Alving, Kjell, Hedlin, Gunilla, Chung, Kian Fan, Adcock, Ian M, Sterk, Peter J, Djukanovic, Ratko, Dahlén, Sven-Erik, Wheelock, Craig E

“…A study which examines whether urinary eicosanoid metabolites can direct asthma phenotyping is presented. Cysteinyl leukotrienes (CysLTs), urinary metabolites…”
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Stratification of asthma phenotypes by airway proteomic signatures by Burg, Dominic, Nicholas, Ben, Strazzeri, Fabio, Staykova, Doroteya, Bansal, Aruna T., Xian, Yang, Corfield, Julie, Wilson, Susan, Ward, Jonathan, Lutter, Rene, Shaw, Dominick E., Bakke, Per S., Caruso, Massimo, Dahlen, Sven-Erik, Fowler, Stephen J., Horváth, Ildikó, Howarth, Peter, Krug, Norbert, Montuschi, Paolo, Sandström, Thomas, Sun, Kai, Riley, John, Auffray, Charles, De Meulder, Bertrand, Lefaudeux, Diane, Sterk, Peter J., Djukanović, Ratko, Ahmed, H., Badorrek, P., Ballereau, S., Baribaud, F., Behndig, A.F., Berglind, A., Berton, A., Bigler, J., Boedigheimer, M.J., Bønnelykke, K., Brinkman, P., Bush, A., Casaulta, C., Chaiboonchoe, A., Davison, T., De Meulder, B., Delin, I., El Hadjam, L., Erzen, D., Faulenbach, C., Fitch, N., Formaggio, E., Gahlemann, M., Garissi, D., Garret, T., Gent, J., Guillmant-Farry, E., Henriksson, E., James, A., Johnson, K., Jullian, N., Kerry, G., Klüglich, M., Knowles, R., Konradsen, J.R., Kretsos, K., Lantz, A.-S., Larminie, C., Latzin, P., Lefaudeux, D., Lemonnier, N., Lowe, L.A., Lutter, R., Mazein, A., McEvoy, L., Mores, N., Murray, C.S., Nething, K., Nordlund, B., Nsubuga, S., Pellet, J., Pison, C., Praticò, G., Valls, M. Puig, Rossios, C., Santini, G., Saqi, M., Sehgal, N., Söderman, P., Sogbesan, A., Spycher, F., Stephan, S., Stokholm, J., Sunther, M., Szentkereszty, M., Tamasi, L., Valente, S., van Aalderen, W.M., van Drunen, C.M., Van Eyll, J., Vyas, A., Yu, W., Zwinderman, A.H.

“…Stratification by eosinophil and neutrophil counts increases our understanding of asthma and helps target therapy, but there is room for improvement in our…”
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Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation by Sparreman Mikus, Maria, Kolmert, Johan, Andersson, Lars I, Östling, Jörgen, Knowles, Richard G, Gómez, Cristina, Ericsson, Magnus, Thörngren, John-Olof, Emami Khoonsari, Payam, Dahlén, Barbro, Kupczyk, Maciej, De Meulder, Bertrand, Auffray, Charles, Bakke, Per S, Beghe, Bianca, Bel, Elisabeth H, Caruso, Massimo, Chanez, Pascal, Chawes, Bo, Fowler, Stephen J, Gaga, Mina, Geiser, Thomas, Gjomarkaj, Mark, Horváth, Ildikó, Howarth, Peter H, Johnston, Sebastian L, Joos, Guy, Krug, Norbert, Montuschi, Paolo, Musial, Jacek, Niżankowska-Mogilnicka, Ewa, Olsson, Henric K, Papi, Alberto, Rabe, Klaus F, Sandström, Thomas, Shaw, Dominick E, Siafakas, Nikolaos M, Uhlén, Mathias, Riley, John H, Bates, Stewart, Middelveld, Roelinde J M, Wheelock, Craig E, Chung, Kian Fan, Adcock, Ian M, Sterk, Peter J, Djukanovic, Ratko, Nilsson, Peter, Dahlén, Sven-Erik, James, Anna

“…Asthma phenotyping requires novel biomarker discovery. To identify plasma biomarkers associated with asthma phenotypes by application of a new proteomic panel…”
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Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort by Alahmadi, Fahad H., Simpson, Andrew J., Gomez, Cristina, Ericsson, Magnus, Thörngren, John-Olof, Wheelock, Craig E., Shaw, Dominic E., Fleming, Louise J., Riley, John, Bates, Stewart, Sousa, Ana R., Bansal, Aruna T., Pandis, Ioannis, Sun, Kai, Caruso, Massimo, Chanez, Pascal, Dahlén, Barbro, Horvath, Ildiko, Krug, Norbert, Singer, Florian, Wagers, Scott, Adcock, Ian M., Djukanovic, Ratko, Dahlen, Sven-Erik, Fowler, Stephen J., Adcock, I.M., Ahmed, H., Auffray, C., Bakke, P., Bansal, A.T., Bates, S., Bel, E.H., Bisgaard, H., Boedigheimer, M.J., Bønnelykke, K., Brinkman, P., Bucchioni, E., Caruso, M., Chaiboonchoe, A., Chanez, P., Chung, F.K., D'Amico, A., Dahlèn, B., Dahlén, S.E., Erpenbeck, V.J., Fichtner, K., Fitch, N., Fleming, L.J., Formaggio, E., Fowler, S.J., Gahlemann, M., Geiser, T., Goss, V., Guo, Y., Hedlin, G., Hekking, P.W., Higenbottam, T., Holweg, C., Horváth, I., Howarth, P., James, A.J., Knowles, R.G., Knox, A.J., Krug, N., Lefaudeux, D., Lutter, R., Manta, A., Matthews, J.G., Meiser, A., Middelveld, R.J.M., Mores, N., Murray, C.S., Musial, J., Myles, D., Pahus, L., Pavlidis, S., Postle, A., Powel, P., Praticò, G., Valls, M. Puig, Rao, N., Riley, J., Roberts, A., Rowe, A., Schofield, J.P.R., Seibold, W., Selby, A., Sigmund, R., Skipp, P.J., Sousa, A.R., Sterk, P.J., Sun, K., Thornton, B., van Aalderen, W.M., Vestbo, J., Vissing, N.H., Wagers, S.S., Weiszhart, Z., Wheelock, C.E., Wilson, S.J.

“…Although estimates of suboptimal adherence to oral corticosteroids in asthma range from 30% to 50%, no ideal method for measurement exists; the impact of poor…”
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Urinary Leukotriene E 4 and Prostaglandin D 2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study by Kolmert, Johan, Gómez, Cristina, Balgoma, David, Sjödin, Marcus, Bood, Johan, Konradsen, Jon R, Ericsson, Magnus, Thörngren, John-Olof, James, Anna, Mikus, Maria, Sousa, Ana R, Riley, John H, Bates, Stewart, Bakke, Per S, Pandis, Ioannis, Caruso, Massimo, Chanez, Pascal, Fowler, Stephen J, Geiser, Thomas, Howarth, Peter, Horváth, Ildikó, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Behndig, Annelie, Shaw, Dominick E, Knowles, Richard G, Holweg, Cécile T J, Wheelock, Åsa M, Dahlén, Barbro, Nordlund, Björn, Alving, Kjell, Hedlin, Gunilla, Chung, Kian Fan, Adcock, Ian M, Sterk, Peter J, Djukanovic, Ratko, Dahlén, Sven-Erik, Wheelock, Craig E

“…New approaches are needed to guide personalized treatment of asthma. To test if urinary eicosanoid metabolites can direct asthma phenotyping. Urinary…”
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