Search Results - "Thétiot‐Laurent, Sophie"

Improving the Antioxidant Properties of Calophyllum inophyllum Seed Oil from French Polynesia: Development and Biological Applications of Resinous Ethanol-Soluble Extracts by Cassien, Mathieu, Mercier, Anne, Thétiot-Laurent, Sophie, Culcasi, Marcel, Ricquebourg, Emilie, Asteian, Alice, Herbette, Gaëtan, Bianchini, Jean-Pierre, Raharivelomanana, Phila, Pietri, Sylvia

“…Tamanu oil from L. has long been used in traditional medicine. Ethanol extraction was found the best strategy for recovering bioactive compounds from the resin…”
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Schistosomiasis Chemotherapy by Thétiot-Laurent, Sophie A.-L., Boissier, Jérôme, Robert, Anne, Meunier, Bernard

“…After malaria, schistosomiasis (or bilharzia) is the second most prevalent disease in Africa, and is occurring in over 70 countries in tropical and subtropical…”
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New Biocompatible β‐Phosphorylated Linear Nitrones Targeting Mitochondria: Protective Effect in Apoptotic Cells by Culcasi, Marcel, Delehedde, Caroline, Esgulian, Mathieu, Cassien, Mathieu, Chocry, Mathieu, Rockenbauer, Antal, Pietri, Sylvia, Thétiot‐Laurent, Sophie

“…The mitochondrion, an essential organelle involved in cellular respiration, energy production, and cell death, is the main cellular source of reactive oxygen…”
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Novel Sterically Crowded and Conformationally Constrained α-Aminophosphonates with a Near-Neutral pKa as Highly Accurate 31P NMR pH Probes. Application to Subtle pH Gradients Determination in Dictyostelium discoideum Cells by Delehedde, Caroline, Culcasi, Marcel, Ricquebourg, Emilie, Cassien, Mathieu, Siri, Didier, Blaive, Bruno, Pietri, Sylvia, Thétiot-Laurent, Sophie

“…In order to discover new 31P NMR markers for probing subtle pH changes (<0.2 pH unit) in biological environments, fifteen new conformationally constrained or…”
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Constrained Cyclic β,γ‐Diamino Acids from Glutamic Acid: Synthesis of Both Diastereomers and Unexpected Kinetic Resolution by Wan, Yang, Auberger, Nicolas, Thétiot‐Laurent, Sophie, Bouillère, Francelin, Zulauf, Anaïs, He, Jiefang, Courtiol‐Legourd, Stéphanie, Guillot, Régis, Kouklovsky, Cyrille, Cote des Combes, Sylvain, Pacaud, Christophe, Devillers, Ingrid, Alezra, Valérie

“…We describe here an efficient synthesis of both diastereomers of cyclic β,γ‐diamino acids starting from l‐glutamic acid, based on the Blaise reaction. We show…”
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New Amino‐Acid‐Based β‐Phosphorylated Nitroxides for Probing Acidic pH in Biological Systems by EPR Spectroscopy by Thétiot‐Laurent, Sophie, Gosset, Gaëlle, Clément, Jean‐Louis, Cassien, Mathieu, Mercier, Anne, Siri, Didier, Gaudel‐Siri, Anouk, Rockenbauer, Antal, Culcasi, Marcel, Pietri, Sylvia

“…There is increasing interest in measuring pH in biological samples by using nitroxides with pH‐dependent electron paramagnetic resonance (EPR) spectra. Aiming…”
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Design of New Probes for Oxidized Amino Acids Localization by Esgulian, Mathieu, Camoin, Luc, Cassien, Mathieu, Toiron, Yves, Pietri, Sylvia, Thétiot-Laurent, Sophie

“…Protein carbonyls (PC) are oxidative damage observed in many diseases. Proteins are possibly the most immediate vehicle for inflicting oxidative damage on…”
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Synthesis and antioxidant properties of pulvinic acids analogues by Nadal, Brice, Thetiot-Laurent, Sophie A.-L., Pin, Serge, Renault, Jean-Philippe, Cressier, Damien, Rima, Ghassoub, Le Roux, Antoine, Meunier, Stéphane, Wagner, Alain, Lion, Claude, Le Gall, Thierry

“…The synthesis of 28 pulvinic acids analogues from dimethyl l-tartrate and the evaluation of their antioxidant properties, using antioxidant capacity assays and…”
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Design and Synthesis of New Antioxidants Predicted by the Model Developed on a Set of Pulvinic Acid Derivatives by Le Roux, Antoine, Kuzmanovski, Igor, Habrant, Damien, Meunier, Stéphane, Bischoff, Pierre, Nadal, Brice, Thetiot-Laurent, Sophie A.-L, Le Gall, Thierry, Wagner, Alain, Novič, Marjana

“…Antioxidative activity expressed as protection of thymidine has been investigated for a set of 30 pulvinic acid derivatives. A combination of in vitro testing…”
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Chemotherapie gegen Schistosomiasis by Thétiot-Laurent, Sophie A.-L., Boissier, Jérôme, Robert, Anne, Meunier, Bernard

“…Schistosomiasis (Bilharziose) ist nach Malaria die zweithäufigste Krankheit in Afrika. Schätzungsweise 600 Millionen Menschen in über 70 Ländern in den Tropen…”
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Metformin-Derived Hybrid Molecules for Glioblastoma Treatment by Delehedde, Caroline, Chocry, Mathieu, Thétiot-Laurent, Sophie, Garrouste, Françoise, Culcasi, Marcel, Kovacic, Hervé O, Pietri, Sylvia

“…Glioblastoma is the most common cerebral tumor in adults. The median survival of glioblastoma patients is 12 months. Metformin is a biguanide used as a…”
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Chitosan as an antioxidant alternative to sulphites in oenology: EPR investigation of inhibitory mechanisms by Castro Marín, Antonio, Culcasi, Marcel, Cassien, Mathieu, Stocker, Pierre, Thétiot-Laurent, Sophie, Robillard, Bertrand, Chinnici, Fabio, Pietri, Sylvia

“…•Metal chelation and free radical scavenging in wine oxidation were tested by EPR.•A dose of 2 g/L of approved chitosan efficiently stabilized an unsulphited…”
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Antidiabetic, antioxidant and anti inflammatory properties of water and n-butanol soluble extracts from Saharian Anvillea radiata in high-fat-diet fed mice by Kandouli, Chouaib, Cassien, Mathieu, Mercier, Anne, Delehedde, Caroline, Ricquebourg, Emilie, Stocker, Pierre, Mekaouche, Mourad, Leulmi, Zineb, Mechakra, Aicha, Thétiot-Laurent, Sophie, Culcasi, Marcel, Pietri, Sylvia

“…According to Saharian traditional medicine, Anvillea radiata Coss. & Dur. (Asteraceae) has been valued for treating a variety of ailments such as…”
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Inhibitory effect of fungoid chitosan in the generation of aldehydes relevant to photooxidative decay in a sulphite-free white wine by Castro Marin, Antonio, Stocker, Pierre, Chinnici, Fabio, Cassien, Mathieu, Thétiot-Laurent, Sophie, Vidal, Nicolas, Riponi, Claudio, Robillard, Bertrand, Culcasi, Marcel, Pietri, Sylvia

“…•Fungoid chitosan reduces the generation of aldehydes during wine photo-oxidation.•In extended oxidative conditions SO2 is a poorer wine anti-browning agent…”
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Foldamers containing γ-amino acid residues or their analogues: structural features and applications by Bouillère, Francelin, Thétiot-Laurent, Sophie, Kouklovsky, Cyrille, Alezra, Valérie

“…Over the past 20 years, the field of foldamers has rapidly increased. Many β-peptides have already been described and shown interesting properties. γ-Peptides…”
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A fluorescent homogeneous assay for myeloperoxidase measurement in biological samples. A positive correlation between myeloperoxidase-generated HOCl level and oxidative status in STZ-diabetic rats by Stocker, Pierre, Cassien, Mathieu, Vidal, Nicolas, Thétiot-Laurent, Sophie, Pietri, Sylvia

“…Myeloperoxidase (MPO) is a key enzyme derived from leukocytes which is associated with the initiation and progression of many inflammatory diseases. Increased…”
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On the vasoprotective mechanisms underlying novel β-phosphorylated nitrones: Focus on free radical characterization, scavenging and NO-donation in a biological model of oxidative stress by Cassien, Mathieu, Petrocchi, Consuelo, Thétiot-Laurent, Sophie, Robin, Maxime, Ricquebourg, Emilie, Kandouli, Chouaib, Asteian, Alice, Rockenbauer, Antal, Mercier, Anne, Culcasi, Marcel, Pietri, Sylvia

“…A series of new hybrid 2-(diethoxyphosphoryl)-N-(benzylidene)propan-2-amine oxide derivatives with different aromatic substitution (PPNs) were synthesized…”
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Peptide screen identifies a new NADPH oxidase inhibitor: impact on cell migration and invasion by Mousslim, Mohamed, Pagano, Alessandra, Andreotti, Nicolas, Garrouste, Françoise, Thuault, Sylvie, Peyrot, Vincent, Parat, Fabrice, Luis, José, Culcasi, Marcel, Thétiot-Laurent, Sophie, Pietri, Sylvia, Sabatier, Jean-Marc, Kovacic, Hervé

“…The NADPH oxidase proteins catalyse the formation of superoxide anion which act as signalling molecules in physiological and pathological processes…”
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Efficient synthesis of both diastereomers of β,γ-diamino acids from phenylalanine and tryptophan by Auberger, Nicolas, Stanovych, Andrii, Thétiot-Laurent, Sophie, Guillot, Régis, Kouklovsky, Cyrille, Cote des Combes, Sylvain, Pacaud, Christophe, Devillers, Ingrid, Alezra, Valérie

“…We synthesized in a few steps both diastereomers of orthogonally protected β,γ-diamino acids starting from l -phenylalanine or l -tryptophan. These final…”
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Novel Sterically Crowded and Conformationally Constrained α-Aminophosphonates with a Near-Neutral pKa as Highly Accurate 31 P NMR pH Probes. Application to Subtle pH Gradients Determination in Dictyostelium discoideum Cells by Delehedde, Caroline, Culcasi, Marcel, Ricquebourg, Emilie, Cassien, Mathieu, Siri, Didier, Blaive, Bruno, Pietri, Sylvia, Thétiot-Laurent, Sophie A.L.

“…In order to discover new 31 P NMR markers for probing subtle pH changes (<0.2 pH unit) in biological environments, fifteen new conformationally constrained or…”
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