Search Results - "Tewari, Deepshikha"
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Cell Type-Specific Extracellular Vesicles and Their Impact on Health and Disease
Published in International journal of molecular sciences (27-02-2024)“…Extracellular vesicles (EVs), a diverse group of cell-derived exocytosed particles, are pivotal in mediating intercellular communication due to their ability…”
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A naphthalimide-based peptide conjugate for concurrent imaging and apoptosis induction in cancer cells by utilizing endogenous hydrogen sulfide
Published in Chemical science (Cambridge) (15-12-2021)“…The excessive production of endogenous hydrogen sulfide (H 2 S) in cancer cells leads to enhanced tumor growth and metastasis. On the other hand, decreased…”
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Tripeptide-induced modulation of mesenchymal stem cell biomechanics stimulates proliferation and wound healing
Published in Chemical communications (Cambridge, England) (10-03-2020)“…We demonstrate the ability of two tripeptides to promote proliferation and modulate the mechanical properties of human mesenchymal stem cells (hMSCs). Notably,…”
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BMP Signaling is Required for Adult Skeletal Homeostasis and Mediates Bone Anabolic Action of Parathyroid Hormone
Published in Bone (New York, N.Y.) (01-11-2016)“…Abstract Bmp2 and Bmp4 genes were ablated in adult mice ( KO ) using a conditional gene knockout technology. Bones were evaluated by microcomputed tomography…”
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Increased Bone Marrow-Specific Adipogenesis by Clofazimine Causes Impaired Fracture Healing, Osteopenia, and Osteonecrosis Without Extraskeletal Effects in Rats
Published in Toxicological sciences (01-11-2019)“…Mycobacterium leprae infection causes bone lesions and osteoporosis, however, the effect of antileprosy drugs on the bone is unknown. We, therefore, set out to…”
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Developmental exposure to As, Cd, and Pb mixture diminishes skeletal growth and causes osteopenia at maturity via osteoblast and chondrocyte malfunctioning in female rats
Published in Toxicological sciences (01-07-2013)“…We studied the effect of metal mixture (MM), comprising As, Cd, and Pb, in developing female rat skeleton from gestation day 5 until postnatal day 60 (P-60)…”
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Ethanol extract of Peperomia pellucida (Piperaceae) promotes fracture healing by an anabolic effect on osteoblasts
Published in Journal of ethnopharmacology (21-06-2013)“…The whole plant or some part of Peperomia pellucida (L.) HBK is used in some parts of Cameroon as a treatment for fracture healing. To evaluate the effect of…”
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Analysis of constituents of the eastern Nigeria mistletoe, Loranthus micranthus linn revealed presence of new classes of osteogenic compounds
Published in Journal of ethnopharmacology (2014)“…Mistletoe extracts (decoctions) are used traditionally in eastern Nigeria for the management of bone pain, post menopausal syndrome and diabetes amongst…”
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Phytoceramides and acylated phytosterol glucosides from Pterospermum acerifolium Willd. seed coat and their osteogenic activity
Published in Phytochemistry (Oxford) (01-09-2012)“…Two phytoceramides (1, 2) and two acylated phytosterol glucosides (3, 4) along with five known compounds (5–9) were isolated from the seed coats of P…”
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Evaluation of Cameroonian plants towards experimental bone regeneration
Published in Journal of ethnopharmacology (07-05-2012)“…Ethanol extracts of Elephantopus mollis leaves and whole plant of Spilanthes africana stimulate bone regeneration in adult Sprague–Dawley rats having fracture…”
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Ovariectomized Rats with Established Osteopenia have Diminished Mesenchymal Stem Cells in the Bone Marrow and Impaired Homing, Osteoinduction and Bone Regeneration at the Fracture Site
Published in Stem cell reviews (01-04-2015)“…We investigated deleterious changes that take place in mesenchymal stem cells (MSC) and its fracture healing competence in ovariectomy (Ovx)-induced…”
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Association of coronary artery disease with polymorphisms of angiotensin-converting enzyme and methylenetetrahydrofolate reductase gene
Published in Indian heart journal (01-07-2006)“…Angiotensin-converting enzyme plays an important role in maintaining blood pressure, while methylenetetrahydrofolate reductase is involved in homocysteine…”
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