Aspergillus vertebral osteomyelitis and epidural abscess

We present the first reported case of Aspergillus vertebral osteomyelitis and epidural abscess in Singapore in a 50-year-old man with post-tuberculous bronchiectasis. The patient presented with acute urinary retention and flaccid paraplegia. Despite surgical debridement and treatment with voriconazo...

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Bibliographic Details
Published in:	Singapore medical journal Vol. 50; no. 4; p. e151
Main Authors:	Tew, C W, Han, F C, Jureen, R, Tey, B H
Format:	Journal Article
Language:	English
Published:	Singapore 01-04-2009
Subjects:	Administration, Oral Antifungal Agents - administration & dosage Aspergillosis - diagnosis Aspergillosis - pathology Aspergillosis - surgery Aspergillus fumigatus Diagnosis, Differential Epidural Abscess - diagnosis Epidural Abscess - pathology Epidural Abscess - surgery Fatal Outcome Humans Infusions, Intravenous Laminectomy Magnetic Resonance Imaging Male Middle Aged Osteomyelitis - diagnosis Osteomyelitis - pathology Osteomyelitis - surgery Pneumonectomy Postoperative Complications - diagnosis Postoperative Complications - pathology Postoperative Complications - surgery Pulmonary Aspergillosis - complications Pulmonary Aspergillosis - pathology Pulmonary Aspergillosis - surgery Pyrimidines - administration & dosage Spinal Cord Compression - diagnosis Spinal Cord Compression - pathology Spinal Cord Compression - surgery Spondylitis - diagnosis Spondylitis - pathology Spondylitis - surgery Thoracic Vertebrae - pathology Thoracic Vertebrae - surgery Triazoles - administration & dosage Voriconazole
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Summary:	We present the first reported case of Aspergillus vertebral osteomyelitis and epidural abscess in Singapore in a 50-year-old man with post-tuberculous bronchiectasis. The patient presented with acute urinary retention and flaccid paraplegia. Despite surgical debridement and treatment with voriconazole, the patient developed multiorgan failure and died two weeks after presentation. Early diagnosis and prompt initiation of treatment are emphasised in the hope of improving the outcome of this aggressive condition.
ISSN:	0037-5675