Search Results - "Teutonico, D."

Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model by Kuepfer, L, Niederalt, C, Wendl, T, Schlender, J‐F, Willmann, S, Lippert, J, Block, M, Eissing, T, Teutonico, D

“…The aim of this tutorial is to introduce the fundamental concepts of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling with a special…”
Get full text

Generating Virtual Patients by Multivariate and Discrete Re-Sampling Techniques by Teutonico, D., Musuamba, F., Maas, H. J., Facius, A., Yang, S., Danhof, M., Della Pasqua, O.

“…Purpose Clinical Trial Simulations (CTS) are a valuable tool for decision-making during drug development. However, to obtain realistic simulation scenarios,…”
Get full text

Characterization of chitosan thiolation and application to thiol quantification onto nanoparticle surface by Bravo-Osuna, I., Teutonico, D., Arpicco, S., Vauthier, C., Ponchel, G.

“…The objective of the present work was to establish a simple and appropriated method for the quantification of thiol groups standing on the surface of…”
Get full text

Prediction of Disease Progression, Treatment Response and Dropout in Chronic Obstructive Pulmonary Disease (COPD) by Musuamba, F. T., Teutonico, D., Maas, H. J., Facius, A., Yang, S., Danhof, M., Della Pasqua, O.

“…Purpose Drug development in chronic obstructive pulmonary disease (COPD) has been characterised by unacceptably high failure rates. In addition to the poor…”
Get full text

Concentration and surface of absorption: Concepts and applications to gastrointestinal patches delivery by Teutonico, D., Montanari, S., Ponchel, G.

“…Gastrointestinal patches represent a novel multiparticulate drug delivery system able to increase the intestinal absorption of drugs with poor bioavailability…”
Get full text

Information campaign planned for Kyrgyzstan by Teutonico, D

Get more information

Characteristics of Men Receiving Vasectomies In the United States, 1998-1999 by Barone, Mark A., Johnson, Christopher H., Luick, Melanie A., Teutonico, Daria L., Magnani, Robert J.

“…CONTEXT: Even though vasectomy is a popular method of contraception in the United States, there is limited information on the characteristics of men choosing…”
Get full text

Effect of Dialysate Calcium Concentrations on Parathyroid Hormone and Calcium Balance During a Single Dialysis Session Using Bicarbonate Hemodialysis: A Crossover Clinical Trial by Basile, Carlo, MD, Libutti, Pasquale, MD, Di Turo, Anna Lucia, MD, Vernaglione, Luigi, MD, Casucci, Francesco, MD, Losurdo, Nicola, MD, Teutonico, Annalisa, MD, Lomonte, Carlo, MD

“…Background In bicarbonate-based hemodialysis, dialysate total calcium (tCa) concentration may have effects on mineral metabolism. Study Design Randomized…”
Get full text

Monitoring Antitumor Efficacy of Rapamycin in Kaposi Sarcoma by Di Paolo, Salvatore, MD, Teutonico, Annalisa, MD, Ranieri, Elena, PhD, Gesualdo, Loreto, MD, Schena, Paolo F., MD

“…Background The clinical challenge for the application of rapamycin and its derivatives as anticancer drugs is the ability to prospectively identify which…”
Get full text

Monitoring Biological Action of Rapamycin in Renal Transplantation by Leogrande, Domenica, MD, Teutonico, Annalisa, MD, Ranieri, Elena, PhD, Saldarelli, Marilisa, PhD, Gesualdo, Loreto, MD, Schena, F. Paolo, MD, Di Paolo, Salvatore, MD

“…Background Inhibition of P70S6 kinase (P70S6K ) phosphorylation in activated T cells is 1 of the major mechanisms by which rapamycin exerts its…”
Get full text

In Reply by Di Paolo, Salvatore, MD, Leogrande, Domenica, MD, Teutonico, Annalisa, MD, Ranieri, Elena, PhD, Saldarelli, Marilisa, PhD, Gesualdo, Loreto, MD, Schena, Paolo F., MD

Get full text