Search Results - "Teuthorn, Andrew P"

Diverting Reactive Intermediates Toward Unusual Chemistry: Unexpected Anthranil Products from Davis–Beirut Reaction by Zhu, Jie S, Son, Jung-Ho, Teuthorn, Andrew P, Haddadin, Makhluf J, Kurth, Mark J, Tantillo, Dean J

“…The discovery of a new variation on the Davis–Beirut reaction is described in which an atypical heterocyclic framework (the anthranil or benzo­[c]­isoxazole…”
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High-Potency Phenylquinoxalinone Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activators by Son, Jung-Ho, Zhu, Jie S, Phuan, Puay-Wah, Cil, Onur, Teuthorn, Andrew P, Ku, Colton K, Lee, Sujin, Verkman, Alan S, Kurth, Mark J

“…We previously identified phenylquinoxalinone CFTRact-J027 (4) as a cystic fibrosis transmembrane conductance regulator (CFTR) activator with an EC50 of ∼200 nM…”
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Davis–Beirut Reaction: Alkoxide versus Hydroxide Addition to the Key o‑Nitrosoimine Intermediate by Zhu, Jie S, Duong, Matthew R, Teuthorn, Andrew P, Lu, Julia Y, Son, Jung-Ho, Haddadin, Makhluf J, Kurth, Mark J

“…Reaction options, alkoxide vs hydroxide vs amine addition to the key intermediate (o-nitrosoimine) generated in the Davis–Beirut reaction of an…”
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Correction to “Diverting Reactive Intermediates Toward Unusual Chemistry: Unexpected Anthranil Products from Davis–Beirut Reaction” by Zhu, Jie S, Son, Jung-Ho, Teuthorn, Andrew P, Haddadin, Makhluf J, Kurth, Mark J, Tantillo, Dean J

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Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation by Cil, Onur, Phuan, Puay-Wah, Son, Jung-Ho, Zhu, Jie S., Ku, Colton K., Tabib, Niloufar Akhavan, Teuthorn, Andrew P., Ferrera, Loretta, Zachos, Nicholas C., Lin, Ruxian, Galietta, Luis J.V., Donowitz, Mark, Kurth, Mark J., Verkman, Alan S.

“…Constipation is a common condition for which current treatments can have limited efficacy. By high-throughput screening, we recently identified a…”
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Phenylquinoxalinone CFTR activator as potential pro-secretory therapy for constipation by Cil, Onur, Phuan, Puay-Wah, Son, Jung-Ho, Zhu, Jie S, Ku, Colton K, Tabib, Niloufar Akhavan, Teuthorn, Andrew P, Ferrera, Loretta, Zachos, Nicholas C, Lin, Ruxian, Galietta, Luis J.V, Donowitz, Mark, Kurth, Mark J, Verkman, A.S

“…Abstract Constipation is a common condition for which current treatments can have limited efficacy. By high-throughput screening we recently identified a…”
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