Search Results - "Teulon, Jacques"
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The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron
Published in Journal of the American Society of Nephrology (01-01-2017)“…Chloride transport by the renal tubule is critical for blood pressure (BP), acid-base, and potassium homeostasis. Chloride uptake from the urinary fluid is…”
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2
Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells
Published in EMBO reports (01-12-2013)“…Mechanical forces associated with fluid flow and/or circumferential stretch are sensed by renal epithelial cells and contribute to both adaptive or disease…”
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3
Acute genetic ablation of pendrin lowers blood pressure in mice
Published in Nephrology, dialysis, transplantation (01-07-2017)“…Pendrin, the chloride/bicarbonate exchanger of β-intercalated cells of the renal connecting tubule and the collecting duct, plays a key role in NaCl…”
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4
Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+channel subunit contrasts with that observed in SeSAME/EAST syndrome
Published in Proceedings of the National Academy of Sciences - PNAS (21-06-2011)“…The heteromeric inwardly rectifying Kir4.1/Kir5.1 K + channel underlies the basolateral K + conductance in the distal nephron and is extremely sensitive to…”
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Kir4.1/Kir5.1 channel forms the major K+ channel in the basolateral membrane of mouse renal collecting duct principal cells
Published in American journal of physiology. Renal physiology (01-06-2008)“…K(+) channels in the basolateral membrane of mouse cortical collecting duct (CCD) principal cells were identified with patch-clamp technique, real-time PCR,…”
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In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening
Published in Scientific reports (03-08-2017)“…The human ClC-Kb channel plays a key role in exporting chloride ions from the cytosol and is known to be involved in Bartter syndrome type 3 when its…”
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7
A calcium-permeable non-selective cation channel in the thick ascending limb apical membrane of the mouse kidney
Published in Biochimica et biophysica acta (01-05-2012)“…Non-selective cation channels have been described in the basolateral membrane of the renal tubule, but little is known about functional channels on the apical…”
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Identification and functional expression of a glutamate- and avermectin-gated chloride channel from Caligus rogercresseyi, a southern Hemisphere sea louse affecting farmed fish
Published in PLoS pathogens (01-09-2014)“…Parasitic sea lice represent a major sanitary threat to marine salmonid aquaculture, an industry accounting for 7% of world fish production. Caligus…”
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9
A Na+- and Cl- -activated K+ channel in the thick ascending limb of mouse kidney
Published in The Journal of general physiology (01-02-2006)“…This study investigates the presence and properties of Na+-activated K+ (K(Na)) channels in epithelial renal cells. Using real-time PCR on mouse microdissected…”
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10
An inward rectifier K+ channel at the basolateral membrane of the mouse distal convoluted tubule: similarities with Kir4-Kir5.1 heteromeric channels
Published in The Journal of physiology (15-01-2002)“…In this study, K + channels present in the basolateral membrane of the distal convoluted tubule (DCT) were investigated using patch-clamp methods. In addition,…”
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11
Properties of an inwardly rectifying K(+) channel in the basolateral membrane of mouse TAL
Published in American journal of physiology. Renal physiology (01-05-2002)“…We investigated the properties of K(+) channels in the basolateral membrane of the cortical thick ascending limb (CTAL) using the patch-clamp technique…”
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12
Defective bicarbonate reabsorption in Kir4.2 potassium channel deficient mice impairs acid-base balance and ammonia excretion
Published in Kidney international (01-02-2020)“…The kidneys excrete the daily acid load mainly by generating and excreting ammonia but the underlying molecular mechanisms are not fully understood. Here we…”
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13
Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels
Published in Physiological reviews (01-01-2015)“…K(+) channels fulfill roles spanning from the control of excitability to the regulation of transepithelial transport. Here we review two groups of K(+)…”
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14
Molecular Aspects of Structure, Gating, and Physiology of pH-Sensitive Background K 2P and Kir K + -Transport Channels
Published in Physiological reviews (01-01-2015)“…K + channels fulfill roles spanning from the control of excitability to the regulation of transepithelial transport. Here we review two groups of K + channels,…”
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15
ClC-K chloride channels: emerging pathophysiology of Bartter syndrome type 3
Published in American journal of physiology. Renal physiology (15-06-2015)“…The mutations in the CLCNKB gene encoding the ClC-Kb chloride channel are responsible for Bartter syndrome type 3, one of the four variants of Bartter syndrome…”
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Vasopressin‐stimulated chloride transport in transimmortalized mouse cell lines derived from the distal convoluted tubule and cortical and inner medullary collecting ducts
Published in Nephrology, dialysis, transplantation (01-02-2001)“…Background. The fine control of NaCl absorption takes place in the distal parts of the renal tubule, but the regulation of Cl− transport in this region has not…”
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17
A new regulator of the vacuolar H+-ATPase in the kidney
Published in Kidney international (01-11-2011)“…Xu et al. identify Slc26a11, a novel member of the Slc26 anion exchanger family, as an electrogenic (Cl−)n/HCO3− exchanger. Functional characterization of this…”
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18
Inhibition of the Calcium Release-activated Calcium (CRAC) Current in Jurkat T Cells by the HIV-1 Envelope Protein gp160
Published in The Journal of biological chemistry (22-02-2002)“…The HIV-1 envelope glycoprotein gp120/160 has pleiotropic effects on T cell function. We investigated whether Ca2+ signaling, a crucial step for T cell…”
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A new mouse model for Bartter's syndrome
Published in American journal of physiology. Renal physiology (01-08-2011)Get more information
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Dual regulation of the native ClC-K2 chloride channel in the distal nephron by voltage and pH
Published in The Journal of general physiology (01-09-2016)“…ClC-K2, a member of the ClC family of Cl(-) channels and transporters, forms the major basolateral Cl(-) conductance in distal nephron epithelial cells and…”
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