Search Results - "Teubner, Wera"
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A medical-toxicological view of tattooing
Published in The Lancet (British edition) (23-01-2016)“…Summary Long perceived as a form of exotic self-expression in some social fringe groups, tattoos have left their maverick image behind and become mainstream,…”
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Identification and localization of soluble sulfotransferases in the human gastrointestinal tract
Published in Biochemical journal (01-06-2007)“…Soluble SULTs (sulfotransferases) are important in the regulation of messenger molecules and the elimination of xenobiotics. However, sulfo-conjugation of…”
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Putting the parts together: Combining in vitro methods to test for skin sensitizing potentials
Published in Regulatory toxicology and pharmacology (01-08-2012)“…► Comparative testing of 54 chemicals in five in vitro tests: DPRA, KeratinoSensTM, LuSens, hCLAT, mMUSST. ► Evaluation of the predictivity of the OECD QSAR…”
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Non-animal test methods for predicting skin sensitization potentials
Published in Archives of toxicology (01-08-2012)“…Contact allergies are complex diseases, and it is estimated that 15–20 % of the general population suffers from contact allergy, with increasing prevalence…”
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Read-across for hazard assessment: the ugly duckling is growing up
Published in Alternatives to laboratory animals (01-12-2015)Get full text
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Indicators for lack of systemic availability of organic pigments
Published in Regulatory toxicology and pharmacology (01-08-2020)“…Experimental data of all 143 organic pigments registered with the European Chemicals Agency, of which 88 were listed in a nanomaterial inventory, was retrieved…”
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Assessment of Pre- and Pro-haptens Using Nonanimal Test Methods for Skin Sensitization
Published in Chemical research in toxicology (16-05-2016)“…Because of ethical and regulatory reasons, several nonanimal test methods to assess the skin sensitization potential of chemicals have been developed and…”
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Computer models versus reality: How well do in silico models currently predict the sensitization potential of a substance
Published in Regulatory toxicology and pharmacology (01-12-2013)“…•In-silico prediction of skin sensitization tested with 100 industrial chemicals.•TIMES-SS, OECD toolbox, Case Ultra, TOPKAT, Vega, ToxWiz and…”
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Local Tolerance Testing under REACH: Accepted Non-animal Methods are Not on Equal Footing with Animal Tests
Published in Alternatives to laboratory animals (01-07-2016)“…In general, no single non-animal method can cover the complexity of any given animal test. Therefore, fixed sets of in vitro (and in chemico) methods have been…”
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Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay
Published in Particle and fibre toxicology (15-04-2016)“…Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging…”
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Analysis of in chemico and in silico methods to predict skin sensitization potentials
Published in Toxicology letters (10-09-2014)Get full text
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Comparative short-term inhalation toxicity of five organic diketopyrrolopyrrole pigments and two inorganic iron-oxide-based pigments
Published in Inhalation toxicology (23-08-2016)“…Diketopyrrolopyrroles (DPP) are a relatively new class of organic high-performance pigments. The present inhalation and particle characterization studies were…”
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Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects
Published in Mutation research (01-10-2001)“…Cytosolic sulphotransferases transfer the sulpho moiety from the cofactor 5'-phosphoadenosine-3'-phosphosulphate (PAPS) to nucleophilic groups of xenobiotics…”
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LuSens: A keratinocyte based ARE reporter gene assay for use in integrated testing strategies for skin sensitization hazard identification
Published in Toxicology in vitro (01-12-2014)“…•The LuSens assay uses a human keratinocyte ARE reporter cell line.•The LuSens addresses a key step of the adverse outcome pathway of skin sensitization.•The…”
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Alternative method in practice: Post-validation experience of the skin sensitization in vitro test strategy
Published in Toxicology letters (28-08-2013)Get full text
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Applicability of in silico models for the prediction of the sensitization potential of industrial chemicals
Published in Toxicology letters (28-08-2013)Get full text
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Predicting sensitization via in silico and in chemico assessment of protein binding
Published in Toxicology letters (17-06-2012)Get full text
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Malignant transformation of human colon epithelial cells by benzo[ c]phenanthrene dihydrodiolepoxides as well as 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5- b]pyridine
Published in Toxicology and applied pharmacology (15-04-2006)“…Polycyclic aromatic hydrocarbons (PAHs) and heterocyclic aromatic amines (HCAs) ingested with food have repeatedly been suggested to be involved in the…”
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Stable expression of rat sulfotransferase 1B1 in V79 cells: activation of benzylic alcohols to mutagens
Published in Carcinogenesis (New York) (01-11-2002)“…We have constructed Chinese hamster V79-derived cell lines (V79-rSULT1B1-A and -B) that express rat sulfotransferase 1B1 (rSULT1B1). Sulfotransferase activity…”
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