Search Results - "Teubner, Wera"

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    Identification and localization of soluble sulfotransferases in the human gastrointestinal tract by Teubner, Wera, Meinl, Walter, Florian, Simone, Kretzschmar, Michael, Glatt, Hansruedi

    Published in Biochemical journal (01-06-2007)
    “…Soluble SULTs (sulfotransferases) are important in the regulation of messenger molecules and the elimination of xenobiotics. However, sulfo-conjugation of…”
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    Putting the parts together: Combining in vitro methods to test for skin sensitizing potentials by Bauch, Caroline, Kolle, Susanne N., Ramirez, Tzutzuy, Eltze, Tobias, Fabian, Eric, Mehling, Annette, Teubner, Wera, van Ravenzwaay, Bennard, Landsiedel, Robert

    Published in Regulatory toxicology and pharmacology (01-08-2012)
    “…► Comparative testing of 54 chemicals in five in vitro tests: DPRA, KeratinoSensTM, LuSens, hCLAT, mMUSST. ► Evaluation of the predictivity of the OECD QSAR…”
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    Non-animal test methods for predicting skin sensitization potentials by Mehling, Annette, Eriksson, Tove, Eltze, Tobias, Kolle, Susanne, Ramirez, Tzutzuy, Teubner, Wera, van Ravenzwaay, Bennard, Landsiedel, Robert

    Published in Archives of toxicology (01-08-2012)
    “…Contact allergies are complex diseases, and it is estimated that 15–20 % of the general population suffers from contact allergy, with increasing prevalence…”
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    Indicators for lack of systemic availability of organic pigments by Stratmann, Heidi, Hellmund, Maria, Veith, Ulrich, End, Nicole, Teubner, Wera

    Published in Regulatory toxicology and pharmacology (01-08-2020)
    “…Experimental data of all 143 organic pigments registered with the European Chemicals Agency, of which 88 were listed in a nanomaterial inventory, was retrieved…”
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    Assessment of Pre- and Pro-haptens Using Nonanimal Test Methods for Skin Sensitization by Urbisch, Daniel, Becker, Matthias, Honarvar, Naveed, Kolle, Susanne Noreen, Mehling, Annette, Teubner, Wera, Wareing, Britta, Landsiedel, Robert

    Published in Chemical research in toxicology (16-05-2016)
    “…Because of ethical and regulatory reasons, several nonanimal test methods to assess the skin sensitization potential of chemicals have been developed and…”
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    Computer models versus reality: How well do in silico models currently predict the sensitization potential of a substance by Teubner, Wera, Mehling, Anette, Schuster, Paul Xaver, Guth, Katharina, Worth, Andrew, Burton, Julien, van Ravenzwaay, Bennard, Landsiedel, Robert

    Published in Regulatory toxicology and pharmacology (01-12-2013)
    “…•In-silico prediction of skin sensitization tested with 100 industrial chemicals.•TIMES-SS, OECD toolbox, Case Ultra, TOPKAT, Vega, ToxWiz and…”
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    Local Tolerance Testing under REACH: Accepted Non-animal Methods are Not on Equal Footing with Animal Tests by Sauer, Ursula G., Hill, Erin H., Curren, Rodger D., Kolle, Susanne N., Teubner, Wera, Mehling, Annette, Landsiedel, Robert

    Published in Alternatives to laboratory animals (01-07-2016)
    “…In general, no single non-animal method can cover the complexity of any given animal test. Therefore, fixed sets of in vitro (and in chemico) methods have been…”
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    Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay by Kolle, Susanne N, Sauer, Ursula G, Moreno, Maria C Rey, Teubner, Wera, Wohlleben, Wendel, Landsiedel, Robert

    Published in Particle and fibre toxicology (15-04-2016)
    “…Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging…”
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    Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects by Glatt, H, Boeing, H, Engelke, C E, Ma, L, Kuhlow, A, Pabel, U, Pomplun, D, Teubner, W, Meinl, W

    Published in Mutation research (01-10-2001)
    “…Cytosolic sulphotransferases transfer the sulpho moiety from the cofactor 5'-phosphoadenosine-3'-phosphosulphate (PAPS) to nucleophilic groups of xenobiotics…”
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    LuSens: A keratinocyte based ARE reporter gene assay for use in integrated testing strategies for skin sensitization hazard identification by Ramirez, Tzutzuy, Mehling, Annette, Kolle, Susanne N., Wruck, Christoph J., Teubner, Wera, Eltze, Tobias, Aumann, Alexandra, Urbisch, Daniel, van Ravenzwaay, Ben, Landsiedel, Robert

    Published in Toxicology in vitro (01-12-2014)
    “…•The LuSens assay uses a human keratinocyte ARE reporter cell line.•The LuSens addresses a key step of the adverse outcome pathway of skin sensitization.•The…”
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    Malignant transformation of human colon epithelial cells by benzo[ c]phenanthrene dihydrodiolepoxides as well as 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5- b]pyridine by Herbst, Uta, Fuchs, Judith Iris, Teubner, Wera, Steinberg, Pablo

    Published in Toxicology and applied pharmacology (15-04-2006)
    “…Polycyclic aromatic hydrocarbons (PAHs) and heterocyclic aromatic amines (HCAs) ingested with food have repeatedly been suggested to be involved in the…”
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    Stable expression of rat sulfotransferase 1B1 in V79 cells: activation of benzylic alcohols to mutagens by Teubner, Wera, Meinl, Walter, Glatt, Hansruedi

    Published in Carcinogenesis (New York) (01-11-2002)
    “…We have constructed Chinese hamster V79-derived cell lines (V79-rSULT1B1-A and -B) that express rat sulfotransferase 1B1 (rSULT1B1). Sulfotransferase activity…”
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