Search Results - "Teuber, Alina"

KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape by Mühlenberg, Thomas, Falkenhorst, Johanna, Schulz, Tom, Fletcher, Benjamin S, Teuber, Alina, Krzeciesa, Dawid, Klooster, Isabella, Lundberg, Meijun, Wilson, Lydia, Lategahn, Jonas, von Mehren, Margaret, Grunewald, Susanne, Tüns, Alicia Isabell, Wardelmann, Eva, Sicklick, Jason K, Brahmi, Mehdi, Serrano, César, Schildhaus, Hans-Ulrich, Sievers, Sonja, Treckmann, Jürgen, Heinrich, Michael C, Raut, Chandrajit P, Ou, Wen-Bin, Marino-Enriquez, Adrian, George, Suzanne, Rauh, Daniel, Fletcher, Jonathan A, Bauer, Sebastian

“…Imatinib resistance in GI stromal tumors (GISTs) is primarily caused by secondary mutations, and clonal heterogeneity of these secondary mutations represents a…”
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Abstract 3887: ATP-binding pocket substitutions as secondary or tertiary in-cis mutations are major on-target ripretinib resistance mechanisms in gastrointestinal stromal tumor by Mühlenberg, Thomas, Falkenhorst, Johanna, Schulz, Tom, Fletcher, Benjamin S., Teuber, Alina, Krzeciesa, Dawid, Klooster, Isabella, Lategahn, Jonas, Ou, Wen-Bin, Lundberg, Meijun, von Mehren, Margaret, Grunewald, Susanne, Tüns, Alicia I., Brahmi, Mehdi, Heinrich, Michael C., Serrano, Cesar, Schildhaus, Hans-Ulrich, Sievers, Sonja, Treckmann, Jürgen, Wilson, Lydia, Raut, Chandrajit P., Marino-Enriquez, Adrian, George, Suzanne, Rauh, Daniel, Fletcher, Jonathan A., Bauer, Sebastian

“…Abstract Introduction: Ripretinib (Rip) is a kinase inhibitor with broad preclinical activity against mutant KIT. Based on the INVICTUS trial, Rip was approved…”
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