Extracts from Cabbage Leaves: Preliminary Results towards a “Universal” Highly-Performant Antibacterial and Antifungal Natural Mixture

Extracts from Cabbage Leaves: Preliminary Results towards a “Universal” Highly-Performant Antibacterial and Antifungal Natural Mixture

As dramatically experienced in the recent world pandemic, viral, bacterial, fungal pathogens constitute very serious concerns in the global context of human health. Regarding this issue, the World Health Organization has promoted research studies that aim to develop new strategies using natural prod...

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Bibliographic Details
Published in:Biology (Basel, Switzerland) Vol. 11; no. 7; p. 1080
Main Authors: Arrais, Aldo, Testori, Fabio, Calligari, Roberta, Gianotti, Valentina, Roncoli, Maddalena, Caramaschi, Alice, Todeschini, Valeria, Massa, Nadia, Bona, Elisa
Format: Journal Article
Language:English
Published: Basel MDPI AG 20-07-2022
MDPI
Subjects:
Agricultural wastes
antibacterial activity
Antibiotics
antifungal activity
Antimicrobial agents
Antimicrobial resistance
Bacteria
Brassica oleracea
C. albicans
Chromatography
Communication
diethyl ether extraction
Environmental impact
Infrared spectroscopy
Lipophilic
Microorganisms
Natural products
Nosocomial infections
Pathogens
savoy cabbage
Solvents
Staphylococcus infections
white cabbage
St Louis Missouri
United States > US
Italy
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Summary:As dramatically experienced in the recent world pandemic, viral, bacterial, fungal pathogens constitute very serious concerns in the global context of human health. Regarding this issue, the World Health Organization has promoted research studies that aim to develop new strategies using natural products. Although they are often competitive with synthetic pharmaceuticales in clinical performance, they lack their critical drawbacks, i.e., the environmental impact and the high economic costs of processing. In this paper, the isolation of a highly performant antibacterial and antifungal lipophilic natural mixture from leaves of savoy and white cabbages is proposed as successful preliminary results for the valorization of agricultural waste produced in cabbage cultivation. The fraction was chemically extracted from vegetables with diethyl ether and tested against two Candida species, as well as Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus reference strains. All the different fractions (active and not active) were chemically characterized by vibrational FT-IR spectroscopy and GC-MS analyses. The extracts showed high growth-inhibition performance on pathogens, thus demonstrating strong application potential. We think that this work, despite being at a preliminary stage, is very promising, both from pharmaceutical and industrial points of view, and can be proposed as a proof of concept for the recovery of agricultural production wastes.
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ISSN:2079-7737
2079-7737
DOI:10.3390/biology11071080