Search Results - "Testi, Claudia"

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    Cryo-EM structure of the human ferritin–transferrin receptor 1 complex by Montemiglio, Linda Celeste, Testi, Claudia, Ceci, Pierpaolo, Falvo, Elisabetta, Pitea, Martina, Savino, Carmelinda, Arcovito, Alessandro, Peruzzi, Giovanna, Baiocco, Paola, Mancia, Filippo, Boffi, Alberto, des Georges, Amédée, Vallone, Beatrice

    Published in Nature communications (08-03-2019)
    “…Human transferrin receptor 1 (CD71) guarantees iron supply by endocytosis upon binding of iron-loaded transferrin and ferritin. Arenaviruses and the malaria…”
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    Journal Article
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    Engineered ferritin for lanthanide binding by Calisti, Lorenzo, Trabuco, Matilde Cardoso, Boffi, Alberto, Testi, Claudia, Montemiglio, Linda Celeste, des Georges, Amédée, Benni, Irene, Ilari, Andrea, Taciak, Bartłomiej, Białasek, Maciej, Rygiel, Tomasz, Król, Magdalena, Baiocco, Paola, Bonamore, Alessandra

    Published in PloS one (13-08-2018)
    “…Ferritin H-homopolymers have been extensively used as nanocarriers for diverse applications in the targeted delivery of drugs and imaging agents, due to their…”
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    Journal Article
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    Exploring the Use of Dimethyl Fumarate as Microglia Modulator for Neurodegenerative Diseases Treatment by Rosito, Maria, Testi, Claudia, Parisi, Giacomo, Cortese, Barbara, Baiocco, Paola, Di Angelantonio, Silvia

    Published in Antioxidants (01-08-2020)
    “…The maintenance of redox homeostasis in the brain is critical for the prevention of the development of neurodegenerative diseases. Drugs acting on brain redox…”
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    Journal Article
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    A novel strategy for molecular interfaces optimization: The case of Ferritin-Transferrin receptor interaction by Di Rienzo, Lorenzo, Milanetti, Edoardo, Testi, Claudia, Montemiglio, Linda Celeste, Baiocco, Paola, Boffi, Alberto, Ruocco, Giancarlo

    “…Protein-protein interactions regulate almost all cellular functions and rely on a fine tune of surface amino acids properties involved on both molecular…”
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    Journal Article
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    Advantages of integrating Brillouin microscopy in multimodal mechanical mapping of cells and tissues by Handler, Chenchen, Testi, Claudia, Scarcelli, Giuliano

    Published in Current opinion in cell biology (01-06-2024)
    “…Recent research has highlighted the growing significance of the mechanical properties of cells and tissues in the proper execution of physiological functions…”
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    Journal Article
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    Structural analysis of the transferrin receptor multifaceted ligand(s) interface by Testi, Claudia, Boffi, Alberto, Montemiglio, Linda Celeste

    Published in Biophysical chemistry (01-11-2019)
    “…The transferrin receptor 1 (TfR1) is one of the key regulators of iron homeostasis for most higher organisms. It mediates cellular iron import through a…”
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    Journal Article
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    Dimethyl Fumarate Reduces Microglia Functional Response to Tissue Damage and Favors Brain Iron Homeostasis by Pagani, Francesca, Testi, Claudia, Grimaldi, Alfonso, Corsi, Giorgio, Cortese, Barbara, Basilico, Bernadette, Baiocco, Paola, De Panfilis, Simone, Ragozzino, Davide, Di Angelantonio, Silvia

    Published in Neuroscience (15-07-2020)
    “…•Dimethyl fumarate (DMF) is used to treat multiple sclerosis (MS), but very little is known on its mechanism of action.•DMF treatment downregulates microglia…”
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    Subcellular localization of the five members of the human steroid 5α-reductase family by Scaglione, Antonella, Montemiglio, Linda Celeste, Parisi, Giacomo, Asteriti, Italia Anna, Bruni, Renato, Cerutti, Gabriele, Testi, Claudia, Savino, Carmelinda, Mancia, Filippo, Lavia, Patrizia, Vallone, Beatrice

    Published in Biochimie open (01-06-2017)
    “…In humans the steroid 5α-reductase (SRD5A) family comprises five integral membrane enzymes that carry out reduction of a double bond in lipidic substrates:…”
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    Journal Article
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