Search Results - "Testanera, Mauricio"

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  1. 1
    Structural and Functional Analysis of a Highly Active Designed Phosphotriesterase for the Detoxification of Organophosphate Nerve Agents Reveals an Unpredicted Conformation of the Active Site Loop

    Structural and Functional Analysis of a Highly Active Designed Phosphotriesterase for the Detoxification of Organophosphate Nerve Agents Reveals an Unpredicted Conformation of the Active Site Loop by Job, Laura, Köhler, Anja, Eichinger, Andreas, Testanera, Mauricio, Escher, Benjamin, Worek, Franz, Skerra, Arne

    Published in Biochemistry (Easton) (21-02-2023)
    “…Neurotoxic organophosphorus compounds (OPs) pose a severe threat if misused in military conflicts or by terrorists. Administration of a hydrolytic enzyme that…”
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  2. 2
    Engineering of a phosphotriesterase with improved stability and enhanced activity for detoxification of the pesticide metabolite malaoxon

    Engineering of a phosphotriesterase with improved stability and enhanced activity for detoxification of the pesticide metabolite malaoxon by Job, Laura, Köhler, Anja, Testanera, Mauricio, Escher, Benjamin, Worek, Franz, Skerra, Arne

    Published in Protein engineering, design and selection (21-01-2023)
    “…Abstract Organophosphorus (OP) pesticides are still widely applied but pose a severe toxicological threat if misused. For in vivo detoxification, the…”
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