Search Results - "Testa, Raymond T"

In vitro susceptibility of characterized β-lactamase-producing strains tested with avibactam combinations by Li, Henry, Estabrook, Mark, Jacoby, George A, Nichols, Wright W, Testa, Raymond T, Bush, Karen

“…Avibactam, a broad-spectrum β-lactamase inhibitor, was tested with ceftazidime, ceftaroline, or aztreonam against 57 well-characterized Gram-negative strains…”
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Biochemical Characterization of Novel Tetrahydrofuranyl 1β-Methylcarbapenems: Stability to Hydrolysis by Renal Dehydropeptidases and Bacterial β-Lactamases, Binding to Penicillin Binding Proteins, and Permeability Properties by YOUJUN YANG, TESTA, R. T, BHACHECH, N, RASMUSSEN, B. A, BUSH, K

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In Vivo Activities of Peptidic Prodrugs of Novel Aminomethyl Tetrahydrofuranyl-1β-Methylcarbapenems by WEISS, W. J, MIKELS, S. M, PETERSEN, P. J, JACOBUS, N. V, BITHA, P, LIN, Y.-I, TESTA, R. T

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In Vitro Activities of Aminomethyl-Substituted Analogs of Novel Tetrahydrofuranyl Carbapenems by WEISS, W. J, PETERSEN, P. J, JACOBUS, N. V, LIN, Y.-I, BITHA, P, TESTA, R. T

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Synthesis and antibacterial activity of 9-substituted minocycline derivatives by Sum, Phaik-Eng, Ross, Adma T., Petersen, Peter J., Testa, Raymond T.

“…Novel sulfonamide and acylamino derivatives of minocycline were synthesized. Many of these derivatives exhibited potent antibacterial activity against…”
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Sulfinemycin, a new anthelmintic antibiotic: fermentation, isolation and structure determination by Lee, T M, Siegel, M M, Morton, G O, Goodman, J J, Testa, R T, Borders, D B

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Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines by Sum, P.-E, Lee, Ving J, Testa, Raymond T, Hlavka, Joseph J, Ellestad, George A, Bloom, Jonathan D, Gluzman, Yakov, Tally, Francis P

“…This report describes the discovery of a new generation of tetracycline antibacterial agents, the "glycylcyclines". These agents are notable for their activity…”
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"Glycylcyclines". 3. 9-Aminodoxycyclinecarboxamides by Barden, Timothy C, Buckwalter, Brian L, Testa, Raymond T, Petersen, Peter J, Lee, Ving J

“…A series of 9-(acylamino)doxycycline derivatives has been prepared. These analogs exhibit good activity against both tetracycline sensitive and tetracycline…”
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LL-AF283 antibiotics, cyclic biphenyl peptides by Chang, C C, Morton, G O, James, J C, Siegel, M M, Kuck, N A, Testa, R T, Borders, D B

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Antibiotic 6640. II. Fermentation, isolation, and properties by Wagman, G H, Testa, R T, Marquez, J A

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Megalomicin, a new macrolide antibiotic complex produced by Micromonospora by Weinstein, M J, Wagman, G H, Marquez, J A, Testa, R T, Oden, E, Waitz, J A

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Susceptibility of enterococci, methicillin-resistant Staphylococcus aureus and Streptococcus pneumoniae to the glycylcyclines by Weiss, W J, Jacobus, N V, Petersen, P J, Testa, R T

“…The in-vitro activities of two glycylcyclines, DMG-MINO and DMG-DMDOT, and several comparative agents were determined against 263 enterococci, 102…”
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Synthesis and structure-activity relationships of novel THF 1β-methylcarbapenems by Lin, Yang-I, Bitha, Panayota, Sakya, Subas M., Strohmeyer, Timothy W., Li, Zhong, Lee, Ving J., Lang, Stanley A., Yang, Youjun, Bhachech, Niraja, Weiss, William J., Petersen, Peter J., Jacobus, Nilda V., Bush, Karen, Testa, Raymond T., Tally, Francis P.

“…A series of twelve highly active aminomethyl-THF 1β-methylcarbapenems 3a-1 were synthesized. Of these, carbapenems 3a-f demonstrated a spectrum of…”
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Peptidic prodrugs of novel aminomethyl-THF 1β-methylcarbapenems by Lin, Yang-I, Bitha, Panayota, Sakya, Subas M., Li, Zhong, Lang, Stanley A., Yang, Youjun, Bhachech, Niraja, Weiss, William J., Petersen, Peter J., Jacobus, Nilda V., Bush, Karen, Testa, Raymond T.

“…Peptidic prodrugs of the five most active aminomethyl-THF 1β-methylcarbapenems were synthesized. Of these, only L-amino acid derivatives from 1a demonstrated…”
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Mono and bis double ester prodrugs of novel aminomethyl-THF 1β-methylcarbapenems by Lin, Yang-I, Bitha, Panayota, Li, Zhong, Sakya, Subas M., Strohmeyer, Timothy W., Lang, Stanley A., Yang, Youjun, Bhachech, Niraja, Weiss, William J., Petersen, Peter J., Jacobus, Nilda V., Bush, Karen, Testa, Raymond T.

“…Mono and bis double ester prodrugs of aminomethyl THF 1β-methylcarbapenems 1 were synthesized. Mono double ester derivatives ( 2, 4 and 7) did not demonstrate…”
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Synthesis and structure-activity relationships of novel THF 1β-methylcarbapenems II by Lin, Yang-I, Bitha, Panayota, Sakya, Subas M., Lang, Stanley A., Yang, Youjun, Weiss, William J., Petersen, Peter J., Bush, Karen, Testa, Raymond T.

“…Two series of active aminomethyl-THF 1β-methylcarbapenem derivatives were synthesized. In general, they were all slightly less active than their parent…”
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In vitro activity of piperacillin/tazobactam against isolates from patients enrolled in clinical trials by Kuck, Nydia A., Jacobus, Nilda V., Spengler, Michael D., Testa, Raymond T.

“…The in vitro activity of piperacillin alone or titrated with a constant concentration of 4 μg/ml tazobactam was evaluated against 3962 baseline pathogens…”
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New antitumor antibiotic, LL-D05139 beta. Fermentation, isolation, structure determination and biological activities by Lee, M D, Fantini, A A, Kuck, N A, Greenstein, M, Testa, R T, Borders, D B

“…The LL-D05139 complex, containing LL-D05139 beta and azaserine, was recovered from the fermentation filtrate of Glycomyces harbinensis (NRRL 15337). A…”
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