Search Results - "Tesson, Bruno M"
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DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules
Published in BMC bioinformatics (06-10-2010)“…Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying…”
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Genetical genomics: spotlight on QTL hotspots
Published in PLoS genetics (01-10-2008)“… [...]a key consideration in eQTL analysis is in the effective design of a permutation strategy to assess statistical significance. [...]the number of…”
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Expression quantitative trait loci are highly sensitive to cellular differentiation state
Published in PLoS genetics (01-10-2009)“…Genetical genomics is a strategy for mapping gene expression variation to expression quantitative trait loci (eQTLs). We performed a genetical genomics…”
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Undifferentiated Embryonic Cell Transcription Factor 1 Regulates ESC Chromatin Organization and Gene Expression
Published in Stem cells (Dayton, Ohio) (01-10-2010)“…Previous reports showed that embryonic stem (ES) cells contain hyperdynamic and globally transcribed chromatin—properties that are important for ES cell…”
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Critical reasoning on causal inference in genome-wide linkage and association studies
Published in Trends in genetics (01-12-2010)“…Genome-wide linkage and association studies of tens of thousands of clinical and molecular traits are currently underway, offering rich data for inferring…”
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Defining gene and QTL networks
Published in Current opinion in plant biology (01-04-2009)“…Current technologies for high-throughput molecular profiling of large numbers of genetically different individuals offer great potential for elucidating the…”
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XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments
Published in Genome biology (09-03-2010)“…We present an extensible software model for the genotype and phenotype community, XGAP. Readers can download a standard XGAP (http://www.xgap.org) or…”
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eQTL analysis in mice and rats
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2009)“…Since the introduction of genetical genomics in 2001, many studies have been published on various organisms, including mouse and rat. Genetical genomics makes…”
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Abstract 5130: Integrative approaches for the identification of therapeutic targets in basal like breast cancer from multi-level molecular data
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Basal-like breast cancer is a molecular subtype of breast carcinoma accounting for up to 15% of cases and associated with a poor prognosis. There is…”
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Defining gene and QTL networks: Genome studies and molecular genetics
Published in Current opinion in plant biology (2009)Get full text
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Expression Quantitative Trait Loci Are Highly Sensitive to Cellular Differentiation State: e1000692
Published in PLoS genetics (01-10-2009)“…Genetical genomics is a strategy for mapping gene expression variation to expression quantitative trait loci (eQTLs). We performed a genetical genomics…”
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Genetical Genomics: Spotlight on QTL Hotspots: e1000232
Published in PLoS genetics (01-10-2008)“…[...]a key consideration in eQTL analysis is in the effective design of a permutation strategy to assess statistical significance. [...]the number of…”
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