Search Results - "Tessema, Efrem N"
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Potential Applications of Phyto-Derived Ceramides in Improving Epidermal Barrier Function
Published in Skin pharmacology and physiology (01-01-2017)“…The outer most layer of the skin, the stratum corneum, consists of corneocytes which are coated by a cornified envelope and embedded in a lipid matrix of…”
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Structural characterization of plant glucosylceramides and the corresponding ceramides by UHPLC-LTQ-Orbitrap mass spectrometry
Published in Journal of pharmaceutical and biomedical analysis (05-01-2021)“…•GlcCERs with 4,8-sphingadienine, 8-sphingenine and 4-hydroxy-8-sphingenine sphingoid bases amid linked to C 14 - 26 FAs were detected.•Lupin bean contains…”
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Delivery of oat-derived phytoceramides into the stratum corneum of the skin using nanocarriers: Formulation, characterization and in vitro and ex-vivo penetration studies
Published in European journal of pharmaceutics and biopharmaceutics (01-06-2018)“…[Display omitted] Deficiency or altered composition of stratum corneum (SC) lipids such as ceramides (CERs), causing skin barrier dysfunction and skin dryness,…”
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Potential application of oat-derived ceramides in improving skin barrier function: Part 1. Isolation and structural characterization
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-10-2017)“…•A reversed phase LC/APCI-MS/MS method was used to separate and characterize the GlcCERs isolated from Ethiopian oat.•Oat GlcCERs consisted of C18 dihydroxy…”
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Development and validation of LC/APCI-MS method for the quantification of oat ceramides in skin permeation studies
Published in Analytical and bioanalytical chemistry (01-08-2018)“…Ceramides (CERs) are the backbone of the intercellular lipid lamellae of the stratum corneum (SC), the outer layer of the skin. Skin diseases such as atopic…”
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Isolation and structural characterization of glucosylceramides from Ethiopian plants by LC/APCI-MS/MS
Published in Journal of pharmaceutical and biomedical analysis (15-07-2017)“…•A reversed phase LC/APCI-MS/MS method for the separation and structural characterization of plant GlcCERs was developed.•C18 di/trihydroxy sphingoid bases…”
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