Search Results - "Terzi, Erdem M."

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis by Alvarez, Samantha W., Sviderskiy, Vladislav O., Terzi, Erdem M., Papagiannakopoulos, Thales, Moreira, Andre L., Adams, Sylvia, Sabatini, David M., Birsoy, Kıvanç, Possemato, Richard

“…Cancers growing in high-oxygen environments, such as lung adenocarcinomas, select for the iron–sulfur cluster synthesizing enzyme NFS1 to support malignant…”
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Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5 by Terzi, Erdem M, Sviderskiy, Vladislav O, Alvarez, Samantha W, Whiten, Gabrielle C, Possemato, Richard

“…Intracellular iron levels are strictly regulated to support homeostasis and avoid iron-mediated ROS production. Loss of iron-sulfur cluster (ISC) synthesis can…”
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Author Correction: NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis by Alvarez, Samantha W., Sviderskiy, Vladislav O., Terzi, Erdem M., Papagiannakopoulos, Thales, Moreira, Andre L., Adams, Sylvia, Sabatini, David M., Birsoy, Kıvanç, Possemato, Richard

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Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε by Sviderskiy, Vladislav O., Blumenberg, Lili, Gorodetsky, Elizabeth, Karakousi, Triantafyllia R., Hirsh, Nicole, Alvarez, Samantha W., Terzi, Erdem M., Kaparos, Efiyenia, Whiten, Gabrielle C., Ssebyala, Shakirah, Tonzi, Peter, Mir, Hannan, Neel, Benjamin G., Huang, Tony T., Adams, Sylvia, Ruggles, Kelly V., Possemato, Richard

“…Knowledge of fundamental differences between breast cancer subtypes has driven therapeutic advances; however, basal-like breast cancer (BLBC) remains…”
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Abstract NG02: NFS1 undergoes positive selection in lung tumors and protects cells from ferroptosis by Alvarez, Samantha W., Sviderskiy, Vladislav O., Terzi, Erdem M., Papagiannakopoulos, Thales, Moreira, Andre L., Adams, Sylvia, Sabatini, David M., Birsoy, Kıvanç, Possemato, Richard L.

“…Abstract Environmental nutrient levels impact cancer cell metabolism, resulting in context-dependent gene essentiality. Here, using RNAi-based loss of function…”
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Iron-Sulfur Cluster Deficiency Can Be Sensed by IRP2 and Regulates Iron Homeostasis and Sensitivity to Ferroptosis Independent of IRP1 and FBXL5 by Terzi, Erdem M

“…Intracellular iron levels are strictly regulated to support homeostasis and avoid iron-mediated ROS production. Loss of iron-sulfur cluster (ISC) synthesis can…”
Get full text