Search Results - "Tervaniemi, M H"
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Low expression of the CCL5 gene and low serum concentrations of CCL5 in severe invasive group a streptococcal disease
Published in Infection (12-06-2024)“…Our objective was to elucidate host dependent factors of disease severity in invasive group A Streptococcal disease (iGAS) using transcriptome profiling of…”
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NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis
Published in Scientific reports (15-03-2016)“…Psoriatic skin differs distinctly from normal skin by its thickened epidermis. Most gene expression comparisons utilize full-thickness biopsies, with…”
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Transient DUX4 expression in human embryonic stem cells induces blastomere-like expression program that is marked by SLC34A2
Published in Stem cell reports (12-07-2022)“…Embryonic genome activation (EGA) is critical for embryonic development. However, our understanding of the regulatory mechanisms of human EGA is still…”
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Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes
Published in BMC genomics (04-06-2018)“…CCHCR1 (Coiled-Coil α-Helical Rod protein 1) is a putative psoriasis candidate gene with the risk alleles CCHCR1*WWCC and *Iso3, the latter inhibiting the…”
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Gene expression analysis of skin grafts and cultured keratinocytes using synthetic RNA normalization reveals insights into differentiation and growth control
Published in BMC genomics (25-06-2015)“…Keratinocytes (KCs) are the most frequent cells in the epidermis, and they are often isolated and cultured in vitro to study the molecular biology of the skin…”
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Optimized single-cell RNA sequencing protocol to study early genome activation in mammalian preimplantation development
Published in STAR protocols (15-09-2023)“…Here, we present a modification of single-cell tagged reverse transcription protocol to study gene expression on a single-cell level or with limited RNA input…”
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Comprehensive characterization of the embryonic factor LEUTX
Published in iScience (17-03-2023)“…The paired-like homeobox transcription factor LEUTX is expressed in human preimplantation embryos between the 4- and 8-cell stages, and then silenced in…”
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Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization
Published in PloS one (26-11-2012)“…CCHCR1 (Coiled-Coil α-Helical Rod protein 1), within the major psoriasis susceptibility locus PSORS1, is a plausible candidate gene with the psoriasis…”
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Transcriptome Analysis of Psoriatic Epidermis
Published in JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)Get full text
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