Search Results - "Tertov, VV"

Carbohydrate composition of protein and lipid components in sialic acid-rich and -poor low density lipoproteins from subjects with and without coronary artery disease by Tertov, VV, Orekhov, AN, Sobenin, IA, Morrisett, JD, Gotto, AM, Guevara, JG

“…Low density lipoprotein (LDL) from patients with coronary heart disease (CHD) caused 78-286% increase in accumulation of cholesterol in human aortic…”
Get full text

Human plasma trans-sialidase causes atherogenic modification of low density lipoprotein by Tertov, V.V., Kaplun, V.V., Sobenin, I.A., Boytsova, E.Yu, Bovin, N.V., Orekhov, A.N.

“…In earlier studies we have found that incubation of low density lipoprotein (LDL) with autologous blood plasma-derived serum leads to a loss of sialic acid…”
Get full text

Low-density lipoprotein modification occurring in human plasma: Possible mechanism of in vivo lipoprotein desialylation as a primary step of atherogenic modification by Tertov, V.V, Kaplun, V.V, Sobenin, I.A, Orekhov, A.N

“…We previously found in human blood a fraction of low-density lipoprotein (LDL) that is characterized by a reduced content of sialic acid. Desialylated LDL also…”
Get full text

Specificity of human trans-sialidase as probed with gangliosides by Nikonova, E.Yu, Tertov, V.V., Sato, C., Kitajima, K., Bovin, N.V.

“…Human blood trans-sialidase able to form and split α2-8 disialic bond in gangliosides. It has been shown that human blood contains a soluble 67kDa enzyme,…”
Get full text

In vitro effect of garlic powder extract on lipid content in normal and atherosclerotic human aortic cells by Orekhov, Alexander N., Tertov, Vladimir V.

“…In the present study, the mechanism of the in vitro effect of garlic powder extract (GPE) on lipid content of cultured human aortic cells was investigated. The…”
Get full text

Apolipoprotein B-Bound Lipids as a Marker for Evaluation of Low Density Lipoprotein Oxidation in Vivo by Tertov, V.V., Kaplun, V.V., Dvoryantsev, S.N., Orekhov, A.N.

“…It has been generally accepted that oxidized low density lipoprotein (LDL) plays an important role in atherogenesis. However, oxidized LDL was not detected in…”
Get full text

Desialylated low density lipoprotein--naturally occurring modified lipoprotein with atherogenic potency by Orekhov, A N, Tertov, V V, Mukhin, D N

“…We have recently established that low density lipoprotein (LDL) of most patients with coronary atherosclerosis differs from the LDL of most healthy subjects by…”
Get more information

Multiple-modified desialylated low density lipoproteins that cause intracellular lipid accumulation. Isolation, fractionation and characterization by Tertov, V V, Sobenin, I A, Gabbasov, Z A, Popov, E G, Jaakkola, O, Solakivi, T, Nikkari, T, Smirnov, V N, Orekhov, A N

“…The basic differences between sialylated (sialic acid rich) and desialylated (sialic acid poor) human low density lipoproteins (LDL) are not fully defined. It…”
Get more information

Metabolism of Native and Naturally Occurring Multiple Modified Low Density Lipoprotein in Smooth Muscle Cells of Human Aortic Intima by Tertov, Vladimir V., Orekhov, Alexander N.

“…The subfraction of low density lipoprotein (LDL) with low sialic acid content that caused accumulation of cholesterol esters in human aortic smooth muscle…”
Get full text

Optimization of the assay for sialic acid determination in low density lipoprotein by Sobenin, I A, Tertov, V V, Orekhov, A N

“…Sialic acid level in blood plasma and circulating glycoproteins is considered to be a marker for a number of pathologic conditions, including atherosclerosis,…”
Get full text

Atherogenic modified LDL in diabetes by Sobenin, I A, Tertov, V V, Orekhov, A N

“…This paper summarizes the recent findings on LDL atherogenic modifications in diabetic patients. LDL from diabetic patients, unlike LDL from healthy subjects,…”
Get full text

Desialylation decreases the resistance of apo B-containing lipoproteins to aggregation and increases their atherogenic potential by Mel'nichenko, A A, Tertov, V V, Ivanova, O A, Aksenov, D V, Sobenin, I A, Popov, E V, Kaplun, V V, Suprun, I V, Panasenko, O M, Orekhov, A N

“…Subfractions of apo B-containing lipoproteins (VLDL and intermediate-density lipoproteins) with reduced content of sialic acid were found in human blood. These…”
Get full text

Modification of low density lipoprotein by desialylation causes lipid accumulation in cultured cells: discovery of desialylated lipoprotein with altered cellular metabolism in the blood of atherosclerotic patients by Orekhov, A N, Tertov, V V, Mukhin, D N, Mikhailenko, I A

“…Low density lipoprotein (LDL) isolated from the blood of healthy donors was partially desialylated by incubating the lipoprotein with sialidase…”
Get more information

Three Types of Naturally Occurring Modified Lipoproteins Induce Intracellular Lipid Accumulation Due to Lipoprotein Aggregation by Tertov, V V, Orekhov, A N, Sobenin, I A, Gabbasov, Z A, Popov, E G, Yaroslavov, A A, Smirnov, V N

“…Low density lipoprotein (LDL) from patients with coronary atherosclerosis and diabetes mellitus as well as in vitro desialylated LDL, glycosylated LDL, and…”
Get full text

Characteristics of low density lipoprotein isolated from circulating immune complexes by Tertov, V.V., Sobenin, I.A., Orekhov, A.N., Jaakkola, O., Solakivi, T., Nikkari, T.

“…Circulating immune complexes (CIC) containing low density lipoprotein (LDL) were recently found in the blood of patients with coronary atherosclerosis. In the…”
Get full text

Antioxidant content in low density lipoprotein and lipoprotein oxidation in vivo and in vitro by Tertov, V V, Sobenin, I A, Kaplun, V V, Orekhov, A N

“…Human blood contains naturally occurring multiple-modified low density lipoprotein (nomLDL) capable of inducing the accumulation of cholesteryl esters in the…”
Get more information

The content of lipoperoxidation products in normal and atherosclerotic human aorta by Tertov, V V, Kaplun, V V, Mikhailova, I A, Suprun, I V, Orekhov, A N

“…To evaluate the role of lipid oxidation in atherogenesis the levels of lipid- and protein-bound products of peroxidation in normal and atherosclerotic areas of…”
Get full text

Modified low density lipoprotein from diabetic patients causes cholesterol accumulation in human intimal aortic cells by Sobenin, I A, Tertov, V V, Koschinsky, T, Bünting, C E, Slavina, E S, Dedov, I I, Orekhov, A N

“…Fifty-five serum samples from 99 Type 1 and 71 serum samples from 81 Type 2 diabetic patients (56% and 88%, respectively) brought about a 1.5-3.5-fold increase…”
Get more information

Human plasma trans-sialidase donor and acceptor specificity by Tertov, V V, Nikonova, E Yu, Nifant'ev, N E, Bovin, N V, Orekhov, A N

“…Earlier we have isolated from human plasma desialylated low density lipoproteins (dLDL) and showed that, first, dLDL induce cholesterol esters…”
Get full text

Direct anti-atherosclerosis-related effects of garlic by Orekhov, A N, Tertov, V V, Sobenin, I A, Pivovarova, E M

“…Direct anti-atherosclerosis-related effects of garlic were studied using cell culture. An aqueous extract from garlic powder (GPE) was added to smooth muscle…”
Get more information