Search Results - "Terry, Samantha YA"
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Mechanisms of inclusion of thallium-201 into Prussian blue nanoparticles for nuclear medicine applications
Published in Journal of materials chemistry. B, Materials for biology and medicine (22-08-2024)“…Prussian blue is known for its high affinity for thallium and other univalent metal cations and has been used as a treatment for radiocaesium and…”
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Second Symposium of the European Working Group on the Radiobiology of Molecular Radionuclide Therapy
Published in Journal of Nuclear Medicine (01-11-2023)“…Molecular radionuclide therapy is a relatively novel anticancer treatment option using radiolabeled, tumor-specific vectors. On binding of these vectors to…”
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Marshalling the Potential of Auger Electron Radiopharmaceutical Therapy
Published in Journal of Nuclear Medicine (01-09-2023)“…Auger electron (AE) radiopharmaceutical therapy (RPT) may have the same therapeutic efficacy as α-particles for oncologic small disease, with lower risks of…”
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Clinical trials in molecular radiotherapy-Tribulations and Triumphs Report of the NCRI CTRad meeting held at the Lift Islington, 8 June 2018
Published in British journal of radiology (01-08-2019)“…It has been almost a decade since the commentary by Gaze and Flux (2010) . The overarching feeling then was that no individual or organisation has taken up the…”
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Status of radiobiology in molecular radionuclide therapy – Hope for the future
Published in Nuclear medicine and biology (01-07-2022)Get full text
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Immuno-PET and Immuno-SPECT of Rheumatoid Arthritis with Radiolabeled Anti-Fibroblast Activation Protein Antibody Correlates with Severity of Arthritis
Published in Journal of Nuclear Medicine (01-05-2015)“…One of the most prominent cell populations playing a role in rheumatoid arthritis (RA) is activated fibroblast-like synoviocytes. Among many other proteins,…”
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Toward Bifunctional Chelators for Thallium-201 for Use in Nuclear Medicine
Published in Bioconjugate chemistry (20-07-2022)“…Auger electron therapy exploits the cytotoxicity of low-energy electrons emitted during radioactive decay that travel very short distances (typically <1 μm)…”
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[68Ga]Ga-THP-Pam: A Bisphosphonate PET Tracer with Facile Radiolabeling and Broad Calcium Mineral Affinity
Published in Bioconjugate chemistry (21-07-2021)“…Calcium minerals such as hydroxyapatite (HAp) can be detected noninvasively in vivo using nuclear imaging agents such as [18F]NaF (available from cyclotrons),…”
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In vitro cytotoxicity of Auger electron-emitting [67Ga]Ga-trastuzumab
Published in Nuclear medicine and biology (01-01-2020)“…Molecular radiotherapy exploiting short-range Auger electron-emitting radionuclides has potential for targeted cancer treatment and, in particular, is an…”
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Validation of the plasmid study to relate DNA damaging effects of radionuclides to those from external beam radiotherapy
Published in Nuclear medicine and biology (01-09-2021)“…The biological consequences of absorbed radiation doses are ill-defined for radiopharmaceuticals, unlike for external beam radiotherapy (EBRT). A reliable…”
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In Vivo Characterization of 4 ^sup 68^Ga-Labeled Multimeric RGD Peptides to Image a^sub v^ß^sub 3^ Integrin Expression in 2 Human Tumor Xenograft Mouse Models
Published in The Journal of nuclear medicine (1978) (01-08-2018)“…αvβ3 integrins play an important role in angiogenesis and cell migration in cancer and are highly expressed on the activated endothelial cells of newly formed…”
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Imaging DNA Damage Repair In Vivo After 177Lu-DOTATATE Therapy
Published in The Journal of nuclear medicine (1978) (01-05-2020)“…Molecular radiotherapy using 177Lu-DOTATATE is a most effective treatment for somatostatin receptor–expressing neuroendocrine tumors. Despite its frequent and…”
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A Clinical Feasibility Study to Image Angiogenesis in Patients with Arteriovenous Malformations Using 68Ga-RGD PET/CT
Published in The Journal of nuclear medicine (1978) (01-02-2020)“…Arteriovenous malformations (AVMs) have an inherent capacity to form new blood vessels, resulting in excessive lesion growth, and this process is further…”
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In Vivo Imaging of Antileukemic Drug Asparaginase Reveals a Rapid Macrophage-Mediated Clearance from the Bone Marrow
Published in Journal of Nuclear Medicine (01-02-2017)“…The antileukemic drug asparaginase, a key component in the treatment of acute lymphoblastic leukemia, acts by depleting asparagine from the blood. However,…”
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Monitoring Therapy Response of Experimental Arthritis with Radiolabeled Tracers Targeting Fibroblasts, Macrophages, or Integrin [alpha]^sub v^[Beta]^sub 3
Published in The Journal of nuclear medicine (1978) (01-03-2016)“…Rheumatoid arthritis is an autoimmune disease resulting in chronic synovial inflammation. Molecular imaging could be used to monitor therapy response, thus…”
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Monitoring Therapy Response of Experimental Arthritis with Radiolabeled Tracers Targeting Fibroblasts, Macrophages, or Integrin [alpha] sigma ub v[Beta] sigma ub 3
Published in The Journal of nuclear medicine (1978) (01-03-2016)“…Rheumatoid arthritis is an autoimmune disease resulting in chronic synovial inflammation. Molecular imaging could be used to monitor therapy response, thus…”
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The Therapeutic Protein Asparaginase Is Efficiently Cleared By Bone Barrow and Spleen Resident Macrophages
Published in Blood (06-12-2014)“…Asparaginase (ASNase) is one of the cornerstones of the multi-drug treatment protocol that is used to treat acute lymphoblastic leukemia (ALL) in pediatric and…”
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Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase
Published in Blood (03-12-2015)“…Asparaginase (ASNase) is one of the cornerstones of the multi-drug treatment protocol that is used to treat acute lymphoblastic leukemia (ALL) in pediatric and…”
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Can^sup 111^In-RGD2 Monitor Response to Therapy in Head and Neck Tumor Xenografts?
Published in The Journal of nuclear medicine (1978) (01-11-2014)“…RGD (arginylglycylaspartic acid)-based imaging tracers allow specific imaging of integrin ... expression, proteins overexpressed during angiogenesis; however,…”
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Can super(111)In-RGD2 Monitor Response to Therapy in Head and Neck Tumor Xenografts?
Published in The Journal of nuclear medicine (1978) (01-11-2014)“…RGD (arginylglycylaspartic acid)-based imaging tracers allow specific imaging of integrin alpha v beta 3 expression, proteins overexpressed during…”
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