Search Results - "Terry, Alvin V."

Neurotoxicity in acute and repeated organophosphate exposure by Naughton, Sean X., Terry, Alvin V.

“…The term organophosphate (OP) refers to a diverse group of chemicals that are found in hundreds of products worldwide. As pesticides, their most common use,…”
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α7 nicotinic acetylcholine receptors as therapeutic targets in schizophrenia: Update on animal and clinical studies and strategies for the future by Terry, Alvin V., Callahan, Patrick M.

“…Schizophrenia is a devastating mental illness and its effective treatment is among the most challenging issues in psychiatry. The symptoms of schizophrenia are…”
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Nicotinic acetylcholine receptors in neurological and psychiatric diseases by Terry, Alvin V., Jones, Keri, Bertrand, Daniel

“…Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are widely distributed both pre- and post-synaptically in the mammalian…”
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Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse by Dinkins, Michael B, Enasko, John, Hernandez, Caterina, Wang, Guanghu, Kong, Jina, Helwa, Inas, Liu, Yutao, Terry, Jr, Alvin V, Bieberich, Erhard

“…Recent evidence implicates exosomes in the aggregation of Aβ and spreading of tau in Alzheimer's disease. In neural cells, exosome formation can be blocked by…”
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Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons by Wen, Lei, Lu, Yi-Sheng, Zhu, Xin-Hong, Li, Xiao-Ming, Woo, Ran-Sook, Chen, Yong-Jun, Yin, Dong-Min, Lai, Cary, Terry, Alvin V. Jr, Vazdarjanova, Almira, Xiong, Wen-Cheng, Mei, Lin

“…Neuregulin 1 (NRG1) is a trophic factor thought to play a role in neural development. Recent studies suggest that it may regulate neurotransmission, mechanisms…”
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Potential roles of gangliosides in chemical-induced neurodegenerative diseases and mental health disorders by Itokazu, Yutaka, Terry, Jr, Alvin V

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An inverse relationship between cortisol and BDNF levels in schizophrenia: Data from human postmortem and animal studies by Issa, George, Wilson, Christina, Terry, Alvin V, Pillai, Anilkumar

“…Abstract Stress and stress-induced glucocorticoids have been implicated in many neuropsychiatric disorders including schizophrenia. In addition, the…”
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Nicotinic ligands as multifunctional agents for the treatment of neuropsychiatric disorders by Terry Jr, Alvin V., Callahan, Patrick M., Hernandez, Caterina M.

“…[Display omitted] The challenges associated with developing more effective treatments for neurologic and psychiatric illness such as Alzheimer’s disease and…”
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Intermittent Stimulation of the Nucleus Basalis of Meynert Improves Working Memory in Adult Monkeys by Liu, Ruifeng, Crawford, Jonathan, Callahan, Patrick M., Terry, Alvin V., Constantinidis, Christos, Blake, David T.

“…Acetylcholine in the neocortex is critical for executive function [1–3]. Degeneration of cholinergic neurons in aging and Alzheimer’s dementia is commonly…”
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Desensitization of nicotinic acetylcholine receptors as a strategy for drug development by Buccafusco, Jerry J, Beach, J Warren, Terry, Jr, Alvin V

“…The specific pharmacological response evoked by a nicotinic acetylcholine receptor (nAChR) agonist is governed by the anatomical distribution and expression of…”
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Age-dependent alterations in nerve growth factor (NGF)-related proteins, sortilin, and learning and memory in rats by Terry, Alvin V, Kutiyanawalla, Ammar, Pillai, Anilkumar

“…Abstract The objective of this study was to evaluate the effects of aging on the performance of specific memory-related tasks in rats as well as to determine…”
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Aged rhesus monkeys: Cognitive performance categorizations and preclinical drug testing by Plagenhoef, Marc R., Callahan, Patrick M., Beck, Wayne D., Blake, David T., Terry, Alvin V.

“…Rodent models have facilitated major discoveries in neurobiology, however, the low success rate of novel medications in clinical trials have led to questions…”
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Manganese-enhanced magnetic resonance imaging method detects age-related impairments in axonal transport in mice and attenuation of the impairments by a microtubule-stabilizing compound by Terry, Alvin V., Beck, Wayne D., Lin, Ping-Chang, Callahan, Patrick M., Rudic, R. Daniel, Hamrick, Mark W.

“…[Display omitted] •Axonal transport is impaired in many age-related neurodegenerative disorders.•The effects of age of axonal transport, however, are poorly…”
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Differential effects of alkaloids on memory in rodents by Callahan, Patrick M., Terry, Alvin V., Peitsch, Manuel C., Hoeng, Julia, Koshibu, Kyoko

“…Nicotinic acetylcholine receptors (nAChRs) play a critical role in the neuropharmacology of learning and memory. As such, naturally occurring alkaloids that…”
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Juvenile Plasma Factors Improve Organ Function and Survival following Injury by Promoting Antioxidant Response by Chu, Xiaogang, Subramani, Kumar, Thomas, Bobby, Terry, Jr, Alvin V, Fulzele, Sadanand, Raju, Raghavan Pillai

“…Studies have shown that factors in the blood of young organisms can rejuvenate the old ones. Studies using heterochronic parabiosis models further reinforced…”
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Cysteamine attenuates the decreases in TrkB protein levels and the anxiety/depression-like behaviors in mice induced by corticosterone treatment by Kutiyanawalla, Ammar, Terry, Jr, Alvin V, Pillai, Anilkumar

“…Stress and glucocorticoid hormones, which are released into the circulation following stressful experiences, have been shown to contribute significantly to the…”
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Health consequences of exposure to aircraft contaminated air and fume events: a narrative review and medical protocol for the investigation of exposed aircrew and passengers by Burdon, Jonathan, Budnik, Lygia Therese, Baur, Xaver, Hageman, Gerard, Howard, C Vyvyan, Roig, Jordi, Coxon, Leonie, Furlong, Clement E, Gee, David, Loraine, Tristan, Terry, Jr, Alvin V, Midavaine, John, Petersen, Hannes, Bron, Denis, Soskolne, Colin L, Michaelis, Susan

“…Thermally degraded engine oil and hydraulic fluid fumes contaminating aircraft cabin air conditioning systems have been well documented since the 1950s. Whilst…”
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Chromosome 21-derived MicroRNAs Provide an Etiological Basis for Aberrant Protein Expression in Human Down Syndrome Brains by Kuhn, Donald E., Nuovo, Gerard J., Terry, Alvin V., Martin, Mickey M., Malana, Geraldine E., Sansom, Sarah E., Pleister, Adam P., Beck, Wayne D., Head, Elizabeth, Feldman, David S., Elton, Terry S.

“…Down syndrome (DS), or Trisomy 21, is the most common genetic cause of cognitive impairment and congenital heart defects in the human population. Bioinformatic…”
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Exposure to variable prenatal stress in rats: Effects on anxiety-related behaviors, innate and contextual fear, and fear extinction by Wilson, Christina A., Vazdarjanova, Almira, Terry, Alvin V.

“…► Prenatal stress leads to decreased innate fear responses to predator odor. ► Prenatal stress leads to impaired fear extinction. ► Prenatal stress leads to…”
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Design and Synthesis of Ranitidine Analogs as Multi-Target Directed Ligands for the Treatment of Alzheimer's Disease by Gao, Jie, Suo, Chen, Tseng, Jui-Heng, Moss, Melissa A, Terry, Jr, Alvin V, Chapman, James

“…The aggregation of amyloid β (Aβ) peptides and deposition of amyloid plaques are implicated in the pathogenesis of Alzheimer's disease (AD). Therefore,…”
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