Search Results - "Terrand, Jerome"

Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation by El Asmar, Zeina, Terrand, Jérome, Jenty, Marion, Host, Lionel, Mlih, Mohamed, Zerr, Aurélie, Justiniano, Hélène, Matz, Rachel L., Boudier, Christian, Scholler, Estelle, Garnier, Jean-Marie, Bertaccini, Diego, Thiersé, Danièle, Schaeffer, Christine, Van Dorsselaer, Alain, Herz, Joachim, Bruban, Véronique, Boucher, Philippe

“…The low density lipoprotein receptor-related protein 1 (LRP1) is a ubiquitously expressed cell surface receptor that protects from intracellular cholesterol…”
Get full text

The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells by Woldt, Estelle, Terrand, Jérome, Mlih, Mohamed, Matz, Rachel L., Bruban, Véronique, Coudane, Fanny, Foppolo, Sophie, El Asmar, Zeina, Chollet, Maria Eugenia, Ninio, Ewa, Bednarczyk, Audrey, Thiersé, Danièle, Schaeffer, Christine, Van Dorsselaer, Alain, Boudier, Christian, Wahli, Walter, Chambon, Pierre, Metzger, Daniel, Herz, Joachim, Boucher, Philippe

“…Vascular calcification is a hallmark of advanced atherosclerosis. Here we show that deletion of the nuclear receptor PPARγ in vascular smooth muscle cells of…”
Get full text

Cholesterol trafficking, lysosomal function, and atherosclerosis by Skeyni, Alaa, Pradignac, Alain, Matz, Rachel L, Terrand, Jérôme, Boucher, Philippe

“…Despite years of study and major research advances over the past 50 years, atherosclerotic diseases continue to rank as the leading global cause of death…”
Get more information

Differential Signaling by Adaptor Molecules LRP1 and ShcA Regulates Adipogenesis by the Insulin-like Growth Factor-1 Receptor by Woldt, Estelle, Matz, Rachel L., Terrand, Jérome, Mlih, Mohamed, Gracia, Céline, Foppolo, Sophie, Martin, Sophie, Bruban, Véronique, Ji, Julie, Velot, Emilie, Herz, Joachim, Boucher, Philippe

“…The low density lipoprotein receptor-related protein (LRP1) is a transmembrane receptor that integrates multiple signaling pathways. Its cytoplasmic domain…”
Get full text

Corticosteroids inhibit cell death induced by doxorubicin in cardiomyocytes: induction of antiapoptosis, antioxidant, and detoxification genes by Chen, Qin M, Alexander, Donnia, Sun, Haipeng, Xie, Lifang, Lin, Yan, Terrand, Jerome, Morrissy, Steve, Purdom, Sally

“…Psychological or physical stress induces an elevation of corticosteroids in the circulating system. We report here that corticosterone (CT) protects…”
Get more information

c-Fos Phosphorylation Induced by H2O2 Prevents Proteasomal Degradation of c-Fos in Cardiomyocytes by Coronella-Wood, June, Terrand, Jerome, Sun, Haipeng, Chen, Qin M.

“…Oxidants cause activation of the AP-1 transcription factor in cardiomyocytes. c-Fos, a component of the AP-1 transcription factor, is transiently induced by…”
Get full text

Wnt5a Promotes Lysosomal Cholesterol Egress and Protects Against Atherosclerosis by Awan, Sara, Lambert, Magalie, Imtiaz, Ali, Alpy, Fabien, Tomasetto, Catherine, Oulad-Abdelghani, Mustapha, Schaeffer, Christine, Moritz, Chloé, Julien-David, Diane, Najib, Souad, Martinez, Laurent O., Matz, Rachel L., Collet, Xavier, Silva-Rojas, Roberto, Böhm, Johann, Herz, Joachim, Terrand, Jérôme, Boucher, Philippe

“…Impairment of cellular cholesterol trafficking is at the heart of atherosclerotic lesions formation. This involves egress of cholesterol from the lysosomes and…”
Get full text

Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation by Abou-Jaoude, Antoine, Badiqué, Lise, Mlih, Mohamed, Awan, Sara, Guo, Sunning, Lemle, Alexandre, Abboud, Clauda, Foppolo, Sophie, Host, Lionel, Terrand, Jérôme, Justiniano, Hélène, Herz, Joachim, Matz, Rachel L., Boucher, Philippe

“…ShcA is an adaptor protein that binds to the cytoplasmic tail of receptor tyrosine kinases and of the Low Density Lipoprotein-related receptor 1 (LRP1), a…”
Get full text

Calcium-mediated activation of pyruvate dehydrogenase in severely injured postischemic myocardium by Terrand, J, Papageorgiou, I, Rosenblatt-Velin, N, Lerch, R

“…Indirect evidence suggests that activity of pyruvate dehydrogenase (PDH) influences recovery of the myocardium after transient ischemia. The present study…”
Get more information

Caveolin-1 regulates glioblastoma aggressiveness through the control of alpha(5)beta(1) integrin expression and modulates glioblastoma responsiveness to SJ749, an alpha(5)beta(1) integrin antagonist by Martin, Sophie, Cosset, Erika C, Terrand, Jérôme, Maglott, Anne, Takeda, Ken, Dontenwill, Monique

“…Caveolin-1 plays a checkpoint function in the regulation of processes often altered in cancer. Although increased expression of caveolin-1 seems to be the norm…”
Get more information

LRP1 Controls Intracellular Cholesterol Storage and Fatty Acid Synthesis through Modulation of Wnt Signaling by Terrand, Járome, Bruban, Váronique, Zhou, Li, Gong, Wanfeng, El Asmar, Zeina, May, Petra, Zurhove, Kai, Haffner, Philipp, Philippe, Claude, Woldt, Estelle, Matz, Rachel L., Gracia, Cáline, Metzger, Daniel, Auwerx, Johan, Herz, Joachim, Boucher, Philippe

“…The low-density lipoprotein receptor-related protein LRP1 is a cell surface receptor with functions in diverse physiological pathways, including lipid…”
Get full text

Caveolin-1 regulates glioblastoma aggressiveness through the control of α5β1 integrin expression and modulates glioblastoma responsiveness to SJ749, an α5β1 integrin antagonist by Martin, Sophie, Cosset, Erika C., Terrand, Jérôme, Maglott, Anne, Takeda, Ken, Dontenwill, Monique

Get full text

The Src Homology and Collagen A (ShcA) Adaptor Protein Is Required for the Spatial Organization of the Costamere/Z-disk Network during Heart Development by Mlih, Mohamed, Host, Lionel, Martin, Sophie, Niederhoffer, Nathalie, Monassier, Laurent, Terrand, Jérôme, Messaddeq, Nadia, Radke, Michael, Gotthardt, Michael, Bruban, Véronique, Kober, Frank, Bernard, Monique, Canet-Soulas, Emmanuelle, Abt-Jijon, Francisco, Boucher, Philippe, Matz, Rachel L.

“…Src homology and collagen A (ShcA) is an adaptor protein that binds to tyrosine kinase receptors. Its germ line deletion is embryonic lethal with abnormal…”
Get full text

Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulation by Xie, Lifang, Terrand, Jerome, Xu, Beibei, Tsaprailis, George, Boyer, Jean, Chen, Qin M.

“…Aims Numerous lines of evidence suggest a role of oxidative stress in initiation and progression of heart failure. We identify novel pathways of oxidative…”
Get full text

p21(WAF1/Cip1/Sdi1) knockout mice respond to doxorubicin with reduced cardiotoxicity by Terrand, Jerome, Xu, Beibei, Morrissy, Steve, Dinh, Thai Nho, Williams, Stuart, Chen, Qin M

“…Doxorubicin (Dox) is an antineoplastic agent that can cause cardiomyopathy in humans and experimental animals. As an inducer of reactive oxygen species and a…”
Get full text

atherosclerosis: gone with the Wnt? by Boucher, Philippe, Matz, Rachel L., Terrand, Jérôme

“…Atherosclerosis, a pathology affecting large and medium-sized arteries, is the major cause of cardiovascular morbidity/mortality in industrialized countries…”
Get full text

p21WAF1/Cip1/Sdi1 knockout mice respond to doxorubicin with reduced cardiotoxicity by Terrand, Jerome, Xu, Beibei, Morrissy, Steve, Dinh, Thai Nho, Williams, Stuart, Chen, Qin M.

“…Doxorubicin (Dox) is an antineoplastic agent that can cause cardiomyopathy in humans and experimental animals. As an inducer of reactive oxygen species and a…”
Get full text

p21 WAF1/Cip1/Sdi1 knockout mice respond to doxorubicin with reduced cardiotoxicity by Terrand, Jerome, Xu, Beibei, Morrissy, Steve, Dinh, Thai Nho, Williams, Stuart, Chen, Qin M.

“…Doxorubicin (Dox) is an antineoplastic agent that can cause cardiomyopathy in humans and experimental animals. As an inducer of reactive oxygen species and a…”
Get full text

Wnt5a Promotes Lysosomal Cholesterol Egress and Protects Against Atherosclerosis by Awan, Sara, Lambert, Magalie, Imtiaz, Ali, Alpy, Fabien, Tomasetto, Catherine, Oulad- Abdelghani, Mustapha, Schaeffer, Christine, Moritz, Chloé, Julien-David, Diane, Najib, Souad, Martinez, Laurent O., Matz, Rachel L., Collet, Xavier, Silva-Rojas, Roberto, Böhm, Johann, Herz, Joachim, Terrand, Jérôme, Boucher, Philippe

Get full text

Pattern of superoxide dismutase enzymatic activity and RNA changes in rat heart ventricles after myocardial infarction by Assem, M, Teyssier, JR, Benderitter, M, Terrand, J, Laubriet, A, Javouhey, A, David, M, Rochette, L

“…A multiplex reverse transcription polymerase chain reaction assay was designed to measure manganese superoxide dismutase (MnSOD) and CuZnSOD mRNAs in the left…”
Get full text