Search Results - "Terra, Patrícia Pereira"
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Changes in serotoninergic and noradrenergic descending pain pathways during painful diabetic neuropathy: The preventive action of IGF1
Published in Neurobiology of disease (01-07-2011)“…Abstract Painful diabetic neuropathy (PDN) induces neuronal hyperactivity at the spinal cord and periaqueductal gray (PAG), a key area in descending…”
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The Role of Ephrins-B1 and -B2 During Fetal Rat Lung Development
Published in Cellular physiology and biochemistry (01-01-2015)“…Background/ Aims: The knowledge of the molecular network that governs fetal lung branching is an essential step towards the discovery of novel therapeutic…”
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Lower NPAS3 expression during the later stages of abnormal lung development in rat congenital diaphragmatic hernia
Published in Pediatric surgery international (01-07-2015)“…Purpose Congenital diaphragmatic hernia (CDH) is characterized by a developmental defect in the diaphragm, pulmonary hypoplasia and pulmonary hypertension…”
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4
Inflammation in Human Heart Failure: Major Mediators and Therapeutic Targets
Published in Frontiers in physiology (11-10-2021)“…Inflammation has been recognized as a major pathophysiological contributor to the entire spectrum of human heart failure (HF), including HF with reduced…”
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Neuronal hyperactivity at the spinal cord and periaqueductal grey during painful diabetic neuropathy: Effects of gabapentin
Published in European journal of pain (01-08-2010)“…Abstract Painful diabetic neuropathy may be due to impairments in descending modulation of nociceptive transmission at the spinal cord. In the present study,…”
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Prenatal microRNA miR-200b Therapy Improves Nitrofen-induced Pulmonary Hypoplasia Associated With Congenital Diaphragmatic Hernia
Published in Annals of surgery (01-05-2019)“…OBJECTIVE:We aimed to evaluate the use of miR-200b as a prenatal transplacental therapy in the nitrofen rat model of abnormal lung development and congenital…”
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Synthesis of a Small Library of Nature-Inspired Xanthones and Study of Their Antimicrobial Activity
Published in Molecules (Basel, Switzerland) (21-05-2020)“…A series of thirteen xanthones - was prepared based on substitutional (appendage) diversity reactions. The series was structurally characterized based on their…”
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Lichen Xanthones as Models for New Antifungal Agents
Published in Molecules (Basel, Switzerland) (12-10-2018)“…Due to the emergence of multidrug-resistant pathogenic microorganisms, the search for new antimicrobial compounds plays an important role in current medicinal…”
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Neuroendocrine factors regulate retinoic acid receptors in normal and hypoplastic lung development
Published in The Journal of physiology (01-08-2015)“…Key points Retinoic acid (RA) and ghrelin levels are altered in human hypoplastic lungs when compared to healthy lungs. Although considerable data have been…”
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10
Endothelitis profile in acute heart failure and cardiogenic shock patients: Endocan as a potential novel biomarker and putative therapeutic target
Published in Frontiers in physiology (11-08-2022)“…Aims: Inflammation-driven endothelitis seems to be a hallmark of acute heart failure (AHF) and cardiogenic shock (CS). Endocan, a soluble proteoglycan secreted…”
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Urinary Cysteinyl Leukotrienes as Biomarkers of Endothelial Activation, Inflammation and Oxidative Stress and Their Relationship with Organ Dysfunction in Human Septic Shock
Published in Biomedicines (01-11-2022)“…Cysteinyl leukotrienes (CysLT) are potent vascular leakage-promoting agents but have been scarcely explored in human septic shock (SS). We evaluated CysLT at…”
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Unique Tracheal Fluid MicroRNA Signature Predicts Response to FETO in Patients With Congenital Diaphragmatic Hernia
Published in Annals of surgery (01-12-2015)“…OBJECTIVE AND BACKGROUND:Our objective was to determine the fetal in vivo microRNA signature in hypoplastic lungs of human fetuses with severe isolated…”
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Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and putative therapeutic targets in COVID-19 patients
Published in Inflammation research (01-03-2023)“…Background Cysteinyl leukotrienes (CysLT) are potent inflammation-promoting mediators, but remain scarcely explored in COVID-19. We evaluated urinary CysLT…”
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New marine-derived indolymethyl pyrazinoquinazoline alkaloids with promising antimicrobial profiles
Published in RSC advances (21-08-2020)“…Due to the emergence of multidrug-resistant pathogenic microorganisms, the search for novel antimicrobials is urgent. Inspired by marine alkaloids, a series of…”
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Lower NPAS^sub 3^ expression during the later stages of abnormal lung development in rat congenital diaphragmatic hernia
Published in Pediatric surgery international (01-07-2015)“…Congenital diaphragmatic hernia (CDH) is characterized by a developmental defect in the diaphragm, pulmonary hypoplasia and pulmonary hypertension. NPAS^sub 3^…”
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Journal Article -
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Looking for Mechanisms Regulating Lung Growth in CDH: Rat and Human Studies
Published 01-01-2015“…Lung development is a complex process that involves a coordinated orchestration of several signalling pathways and mechanisms in order to growth normally…”
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Dissertation