Search Results - "Terence G. Meighan"

Development of a thermal spray coating aerosol generator and inhalation exposure system by Afshari, Aliakbar A., McKinney, Walter, Cumpston, Jared L., Leonard, Howard D., Cumpston, James B., Meighan, Terence G., Jackson, Mark, Friend, Sherri, Kodali, Vamsi, Lee, Eun Gyung, Antonini, James M.

“…[Display omitted] •An automated thermal spray coating generator and inhalation exposure system was designed and developed.•The system can generate a consistent…”
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Welding fume inhalation exposure and high-fat diet change lipid homeostasis in rat liver by Boyce, Greg R., Shoeb, Mohammad, Kodali, Vamsi, Meighan, Terence G., Roach, Katherine A., McKinney, Walter, Stone, Samuel, Powell, Matthew J., Roberts, Jenny R., Zeidler-Erdely, Patti C., Erdely, Aaron, Antonini, James M.

“…It is estimated that greater than 1 million workers are exposed to welding fume (WF) by inhalation daily. The potentially toxic metals found in WF are known to…”
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Aerosol characterization and pulmonary responses in rats after short-term inhalation of fumes generated during resistance spot welding of galvanized steel by Antonini, James M, Afshari, Aliakbar, Meighan, Terence G, McKinney, Walter, Jackson, Mark, Schwegler-Berry, Diane, Burns, Dru A, LeBouf, Ryan F, Chen, Bean T, Shoeb, Mohammad, Zeidler-Erdely, Patti C

“…Resistance spot welding is a common process to join metals in the automotive industry. Adhesives are often used as sealers to seams of metals that are joined…”
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Absence of lung tumor promotion with reduced tumor size in mice after inhalation of copper welding fumes by Zeidler-Erdely, Patti C, Kodali, Vamsi, Falcone, Lauryn M, Mercer, Robert, Leonard, Stephen S, Stefaniak, Aleksandr B, Grose, Lindsay, Salmen, Rebecca, Trainor-DeArmitt, Taylor, Battelli, Lori A, McKinney, Walter, Stone, Samuel, Meighan, Terence G, Betler, Ella, Friend, Sherri, Hobbie, Kristen R, Service, Samantha, Kashon, Michael, Antonini, James M, Erdely, Aaron

“…Abstract Welding fumes are a Group 1 (carcinogenic to humans) carcinogen as classified by the International Agency for Research on Cancer. The process of…”
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Evaluation of the Pulmonary Toxicity of a Fume Generated from a Nickel-, Copper-Based Electrode to be Used as a Substitute in Stainless Steel Welding by Antonini, James M., Badding, Melissa A., Meighan, Terence G., Keane, Michael, Leonard, Stephen S., Roberts, Jenny R.

“…Epidemiology has indicated a possible increase in lung cancer among stainless steel welders. Chromium (Cr) is a primary component of stainless steel welding…”
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Lung toxicity, deposition, and clearance of thermal spray coating particles with different metal profiles after inhalation in rats by Antonini, James M, Kodali, Vamsi, Meighan, Terence G, McKinney, Walter, Cumpston, Jared L, Leonard, Howard D, Cumpston, James B, Friend, Sherri, Leonard, Stephen S, Andrews, Ronnee, Zeidler-Erdely, Patti C, Erdely, Aaron, Lee, Eun Gyung, Afshari, Aliakbar A

“…Thermal spray coating is a process in which molten metal is sprayed onto a surface. Little is known about the health effects associated with these aerosols…”
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Effect of Age, High-Fat Diet, and Rat Strain on Serum Biomarkers and Telomere Length and Global DNA Methylation in Peripheral Blood Mononuclear Cells by Antonini, James M., Kodali, Vamsi, Meighan, Terence G., Roach, Katherine A., Roberts, Jenny R., Salmen, Rebecca, Boyce, Greg R., Zeidler-Erdely, Patti C., Kashon, Michael, Erdely, Aaron, Shoeb, Mohammad

“…The objective of the current study was to determine if age, diet, and genetic disposition (animal strain) in an animal model had early effects on specific…”
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Bioactivity of Circulatory Factors After Pulmonary Exposure to Mild or Stainless Steel Welding Fumes by Kodali, Vamsi, Shoeb, Mohammad, Meighan, Terence G, Eye, Tracy, Friend, Sherri A, Hubczak, John, Kashon, Michael L, Zeidler-Erdely, Patti C, Antonini, James M, Erdely, Aaron

“…Studies suggest that alterations in circulating factors are a driver of pulmonary-induced cardiovascular dysfunction. To evaluate, if circulating factors…”
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Inhalation of gas metal arc–stainless steel welding fume promotes lung tumorigenesis in A/J mice by Falcone, Lauryn M., Erdely, Aaron, Meighan, Terence G., Battelli, Lori A., Salmen, Rebecca, McKinney, Walter, Stone, Samuel, Cumpston, Amy, Cumpston, Jared, Andrews, Ronnee N., Kashon, Michael, Antonini, James M., Zeidler-Erdely, Patti C.

“…Epidemiologic studies suggest an increased risk of lung cancer with exposure to welding fumes, but controlled animal studies are needed to support this…”
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Altered ion transport in normal human bronchial epithelial cells following exposure to chemically distinct metal welding fume particles by Fedan, Jeffrey S., Thompson, Janet A., Meighan, Terence G., Zeidler-Erdely, Patti C., Antonini, James M.

“…Welding fume inhalation causes pulmonary toxicity, including susceptibility to infection. We hypothesized that airway epithelial ion transport is a target of…”
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Comparison of cell counting methods in rodent pulmonary toxicity studies: automated and manual protocols and considerations for experimental design by Zeidler-Erdely, Patti C., Antonini, James M., Meighan, Terence G., Young, Shih-Houng, Eye, Tracy J., Hammer, Mary Ann, Erdely, Aaron

“…Pulmonary toxicity studies often use bronchoalveolar lavage (BAL) to investigate potential adverse lung responses to a particulate exposure. The BAL cellular…”
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Induction of miR-21-PDCD4 signaling by UVB in JB6 cells involves ROS-mediated MAPK pathways by Hou, Lichao, Bowman, Linda, Meighan, Terence G., Pratheeshkumar, Poyil, Shi, Xianglin, Ding, Min

“…Ultraviolet (UV) irradiation plays a major role in the development of human skin cancer. The present study examined the alterations of miR-21-PDCD4 signaling…”
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Lung tumor promotion by chromium-containing welding particulate matter in a mouse model by Zeidler-Erdely, Patti C, Meighan, Terence G, Erdely, Aaron, Battelli, Lori A, Kashon, Michael L, Keane, Michael, Antonini, James M

“…Epidemiology suggests that occupational exposure to welding particulate matter (PM) may increase lung cancer risk. However, animal studies are lacking to…”
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Oxidative Stress, DNA Methylation, and Telomere Length Changes in Peripheral Blood Mononuclear Cells after Pulmonary Exposure to Metal-Rich Welding Nanoparticles by Shoeb, Mohammad, Kodali, Vamsi K, Farris, Breanne Y, Bishop, Lindsey M, Meighan, Terence G, Salmen, Rebecca, Eye, Tracy, Friend, Sherri, Schwegler-Berry, Diane, Roberts, Jenny R, Zeidler-Erdely, Patti C, Erdely, Aaron, Antonini, James M

“…Welding fume is a complex mixture of different potentially cytotoxic and genotoxic metals, such as chromium (Cr), manganese (Mn), nickel (Ni), and iron (Fe)…”
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Neurotoxicity following acute inhalation of aerosols generated during resistance spot weld-bonding of carbon steel by Sriram, Krishnan, Jefferson, Amy M., Lin, Gary X., Afshari, Aliakbar, Zeidler-Erdely, Patti C., Meighan, Terence G., McKinney, Walter, Jackson, Mark, Cumpston, Amy, Cumpston, Jared L., Leonard, Howard D., Frazer, David G., Antonini, James M.

“…Abstract Welding generates complex metal aerosols, inhalation of which is linked to adverse health effects among welders. An important health concern of…”
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Induction of miR-21-PDCD4 signaling by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS-mediated MAPK pathways by Hou, Lichao, Bowman, Linda, Meighan, Terence G, Shi, Xianglin, Ding, Min

“…Tungsten carbide-cobalt (WC-Co) nanoparticle composites have wide applications because of their hardness and toughness. WC-Co was classified as "probably…”
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Effects of acute inhalation of aerosols generated during resistance spot welding with mild-steel on pulmonary, vascular and immune responses in rats by Zeidler-Erdely, Patti C., Meighan, Terence G., Erdely, Aaron, Fedan, Jeffrey S., Thompson, Janet A., Bilgesu, Suzan, Waugh, Stacey, Anderson, Stacey, Marshall, Nikki B., Afshari, Aliakbar, McKinney, Walter, Frazer, David G., Antonini, James M.

“…Abstract Spot welding is used in the automotive and aircraft industries, where high-speed, repetitive welding is needed to join thin sections of metal. Epoxy…”
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Development and characterization of a resistance spot welding aerosol generator and inhalation exposure system by Afshari, Aliakbar, Zeidler-Erdely, Patti C., McKinney, Walter, Chen, Bean T., Jackson, Mark, Schwegler-Berry, Diane, Friend, Sherri, Cumpston, Amy, Cumpston, Jared L., Donny Leonard, H., Meighan, Terence G., Frazer, David G., Antonini, James M.

“…Abstract Limited information exists regarding the health risks associated with inhaling aerosols that are generated during resistance spot welding of metals…”
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Altered Ion Transport in Normal Human Bronchial Epithelial (NHBE) Cells Following Exposure to Metal Welding Particles by Fedan, Jeffrey S, Thompson, Janet A, Meighan, Terence G, Erdely, Patti C, Antonini, James M

“…Abstract only Inhalation of welding fumes is associated with adverse effects in the pulmonary system, including susceptibility to infection. Several types of…”
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Comparative Microscopic Study of Human and Rat Lungs after Exposure to Welding Fume by Antonini, James Michael, Roberts, Jenny R, Meighan, Terence G, Schwegler‐Berry, Diane, Mercer, Robert R

“…Abstract only Welding generates complex aerosols of hazardous metal fumes. Animal models and the ability to control the welding fume (WF) exposure have helped…”
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