Search Results - "Terada, Tatsuhiro"
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Extrastriatal spreading of microglial activation in Parkinson’s disease: a positron emission tomography study
Published in Annals of nuclear medicine (01-10-2016)“…Background The neuroinflammatory glial response contributes to the degenerative process in Parkinson’s disease (PD). However, the pattern of microglial…”
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Increased anteroventral striatal dopamine transporter and motor recovery after subthalamic deep brain stimulation in Parkinson's disease
Published in Journal of neurosurgery (01-08-2022)“…Subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease is effective; however, its mechanism is unclear. To investigate the degree of…”
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Neuroinflammation following anti-parkinsonian drugs in early Parkinson’s disease: a longitudinal PET study
Published in Scientific reports (27-02-2024)“…The progression of neuroinflammation after anti-parkinsonian therapy on the Parkinson’s disease (PD) brain and in vivo evidence of the therapy purporting…”
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tDCS-induced modulation of GABA concentration and dopamine release in the human brain: A combination study of magnetic resonance spectroscopy and positron emission tomography
Published in Brain stimulation (01-01-2021)“…Transcranial direct current stimulation (tDCS) to the dorsolateral prefrontal cortex (DLPFC) hypothetically modulates cognitive functions by facilitating or…”
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Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer's disease
Published in Molecular neurodegeneration (26-04-2021)“…Mitochondrial electron transport chain abnormalities have been reported in postmortem pathological specimens of Alzheimer's disease (AD). However, it remains…”
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Alterations in α4β2 nicotinic receptors in cognitive decline in Alzheimer’s aetiopathology
Published in Brain (London, England : 1878) (01-10-2013)“…Nicotinic acetylcholine receptor subtype α4β2 is considered important in the regulation of attention and memory, and cholinergic degeneration is known as one…”
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Mitochondrial complex I abnormalities underlie neurodegeneration and cognitive decline in Alzheimer’s disease
Published in European journal of neurology (01-05-2022)“…Background and purpose Abnormal mitochondrial metabolism has been described in the Alzheimer's disease (AD) brain. However, the relationship between AD…”
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In vivo Illustration of Altered Dopaminergic and GABAergic Systems in Early Parkinson's Disease
Published in Frontiers in neurology (17-05-2022)“…Changes in γ-aminobutyric acid (GABA) function are noted in patients with Parkinson's disease (PD) who have some non-motor impairments. However,…”
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Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin
Published in Biochimica et biophysica acta (01-11-2010)“…Ceruloplasmin plays an essential role in cellular iron efflux by oxidizing ferrous iron exported from ferroportin. Ferroportin is posttranslationally regulated…”
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Neuroinflammation following disease modifying therapy in multiple sclerosis: A pilot positron emission tomography study
Published in Journal of the neurological sciences (15-02-2018)“…Chronic activation of microglia accelerates the neurodegenerative process in multiple sclerosis (MS). Although disease modifying therapy (DMT) is reportedly…”
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In vivo Depiction of α7 Nicotinic Receptor Loss for Cognitive Decline in Alzheimer's Disease
Published in Journal of Alzheimer's disease (2018)“…The α7 subtype of the nicotinic acetylcholine receptor (nAChR) is considered important in higher cognitive functions, and cholinergic loss underpins the…”
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Coexistence of cerebral hypometabolism and neuroinflammation in the thalamo-limbic-brainstem region in young women with functional somatic syndrome
Published in EJNMMI research (20-03-2020)“…Background Functional somatic syndrome (FSS) is a disorder characterized by clusters of medically unexplained symptoms. Some women suffer from persistent FSS…”
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Alterations in Phase-Related Prefrontal Activation During Cognitive Tasks and Nicotinic α4β2 Receptor Availability in Alzheimer's Disease
Published in Journal of Alzheimer's disease (03-08-2016)“…Evidence shows that the cholinergic system plays an important role in regulating working memory and that working memory-related prefrontal activation decreases…”
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Case of presymptomatic aceruloplasminemia treated with deferasirox
Published in Hepatology research (01-11-2014)“…Aceruloplasminemia is an autosomal recessive disease characterized by an abnormal iron metabolism. The absence of ferroxidase activity caused by mutation of…”
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Alterations in serotonin transporter and body image-related cognition in anorexia nervosa
Published in NeuroImage clinical (01-01-2019)“…The serotonin system has been implicated in the pathophysiology of anorexia nervosa (AN). A recent report proposed that body image distortion (BID), a core…”
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Effectiveness of Oral Iron Chelator Treatment with Deferasirox in an Aceruloplasminemia Patient with a Novel Ceruloplasmin Gene Mutation
Published in Internal Medicine (01-01-2013)“…A 59-year-old man presented with refractory anemia, choreoathetosis in the left upper extremity, an unsteady gait and cognitive dysfunction. The laboratory…”
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In vivo Mesolimbic D2/3 Receptor Binding Predicts Posttherapeutic Clinical Responses in Restless Legs Syndrome: A Positron Emission Tomography Study
Published in Journal of cerebral blood flow and metabolism (01-04-2012)“…Although D2/3 agonists have been used as a first-line medication for idiopathic restless legs syndrome (iRLS), findings on D2/3 receptors have been…”
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Frontal assessment battery and frontal atrophy in amyotrophic lateral sclerosis
Published in Brain and behavior (01-06-2017)“…Objectives To determine the potential utility of the frontal assessment battery (FAB) in assessing cognitive impairments in amyotrophic lateral sclerosis…”
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Effect of Subthalamic Nucleus Stimulation during Exercise on the Mesolimbocortical Dopaminergic Region in Parkinson'S Disease: A Positron Emission Tomography Study
Published in Journal of cerebral blood flow and metabolism (01-03-2013)“…To elucidate the dynamic effects of deep brain stimulation (DBS) in the subthalamic nucleus (STN) during activity on the dopaminergic system, 12 PD patients…”
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The Possible Link between GABAergic Dysfunction and Cognitive Decline in a Patient with Idiopathic Hypoparathyroidism
Published in Internal Medicine (01-01-2015)“…Idiopathic hypoparathyroidism (IHP) is accompanied by cognitive impairment. We report the case of a 70-year-old IHP patient with cognitive disturbance. Brain…”
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