Search Results - "Terabe, Fumitaka"

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis by Serada, Satoshi, Fujimoto, Minoru, Mihara, Masahiko, Koike, Nobuo, Ohsugi, Yoshiyuki, Nomura, Shintaro, Yoshida, Hiroto, Nishikawa, Teppei, Terabe, Fumitaka, Ohkawara, Tomoharu, Takahashi, Tsuyoshi, Ripley, Barry, Kimura, Akihiro, Kishimoto, Tadamitsu, Naka, Tetsuji

“…The development of Th17 cells is a key event in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), a murine model of human multiple sclerosis…”
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Blockade of Interleukin-6 Receptor Alleviates Disease in Mouse Model of Scleroderma by Kitaba, Shun, Murota, Hiroyuki, Terao, Mika, Azukizawa, Hiroaki, Terabe, Fumitaka, Shima, Yoshihito, Fujimoto, Minoru, Tanaka, Toshio, Naka, Tetsuji, Kishimoto, Tadamitsu, Katayama, Ichiro

“…Activation of fibroblasts by interleukin-6 (IL-6) is implicated in the pathogenesis of scleroderma, suggesting that the inhibition of fibroblast activation may…”
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Blockade of interleukin-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses by Hohki, Satoshi, Ohguro, Nobuyuki, Haruta, Hiroshi, Nakai, Kei, Terabe, Fumitaka, Serada, Satoshi, Fujimoto, Minoru, Nomura, Shintaro, Kawahata, Hirohisa, Kishimoto, Tadamitsu, Naka, Tetsuji

“…The aim of this study was to investigate the effect of anti-mouse IL-6 receptor monoclonal antibody (MR16-1) treatment on CD4 T cell differentiation and…”
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Suppressor of cytokine signaling-1 ameliorates dextran sulfate sodium-induced colitis in mice by Horino, Jiro, Fujimoto, Minoru, Terabe, Fumitaka, Serada, Satoshi, Takahashi, Tsuyoshi, Soma, Yoshihito, Tanaka, Kentaro, Chinen, Takatoshi, Yoshimura, Akihiko, Nomura, Shintaro, Kawase, Ichiro, Hayashi, Norio, Kishimoto, Tadamitsu, Naka, Tetsuji

“…Inflammatory bowel disease (IBD) is a chronic disorder of the gastrointestinal tract. Although the etiology and pathogenesis of IBD remain unknown,…”
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Green tea polyphenol epigallocatechin gallate inhibits cell signaling by inducing SOCS1 gene expression by Ripley, Barry J. M., Fujimoto, Minoru, Serada, Satoshi, Ohkawara, Tomoharu, Nishikawa, Teppei, Terabe, Fumitaka, Matsukawa, Yuko, Stephanou, Anastasis, Knight, Richard A., Isenberg, David A., Latchman, David S., Kishimoto, Tadamitsu, Naka, Tetsuji

“…Therapeutic effects of green tea involve an inhibitory function of its constituent polyphenol epigallocatechin gallate (EGCG) on cell signaling. The…”
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Imatinib mesylate inhibited rat adjuvant arthritis and PDGF-dependent growth of synovial fibroblast via interference with the Akt signaling pathway by Terabe, Fumitaka, Kitano, Masayasu, Kawai, Mari, Kuwahara, Yusuke, Hirano, Toru, Arimitsu, Junsuke, Hagihara, Keisuke, Shima, Yoshihito, Narazaki, Masashi, Tanaka, Toshio, Kawase, Ichiro, Sano, Hajime, Ogata, Atsushi

“…Overgrowth of the synovium plays an important role in the pathogenesis of rheumatoid arthritis (RA). Platelet-derived growth factor (PDGF) is one of the most…”
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A case of pancreatic pseudocyst associated with pancreatic cancer successfully treated with endoscopic pseudocyst drainage, which allowed continuation of chemotherapy by Maegawa, Yuki, Terabe, Fumitaka, Ueda, Takashi, Ito, Motoyo, Miyoshi, Kouhei, Nakamura, Masashi, Tanaka, Eri, Suemura, Shigeki, Tatsumi, Osamu, Fukui, Hiroyuki

“…We report a case of pancreatic pseudocyst associated with pancreatic cancer that was successfully treated with endoscopic pseudocyst drainage, which allowed…”
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CORRELATIONS BETWEEN VIDEO CAPSULE ENDOSCOPIC FINDINGS AND CLINICAL ACTIVITY IN CROHN'S DISEASE by Morita, Eijiro, Tanaka, Torao, Nakamura, Tetsuya, Terabe, Fumitaka, Hirata, Ichiro, Katsu, Kenichi, Takazoe, Masakazu, Terano, Akira

“…Background and Aims:  Video capsule endoscopy (VCE) has become increasingly important as a simple method for observing the entire small intestine. The…”
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Serum leucine‐rich alpha‐2 glycoprotein is a disease activity biomarker in ulcerative colitis by Serada, Satoshi, Fujimoto, Minoru, Terabe, Fumitaka, Iijima, Hideki, Shinzaki, Shinichiro, Matsuzaki, Shinya, Ohkawara, Tomoharu, Nezu, Riichiro, Nakajima, Sachiko, Kobayashi, Taku, Plevy, Scott Eric, Takehara, Tetsuo, Naka, Tetsuji

“…Background: Reliable biomarkers for monitoring disease activity have not been clinically established in ulcerative colitis (UC). This study aimed to…”
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Aberrant expression of glycosylation in juvenile gastrointestinal stromal tumors by Takahashi, Tsuyoshi, Naka, Tetsuji, Fujimoto, Minoru, Serada, Satoshi, Horino, Jirou, Terabe, Fumitaka, Hirota, Seiichi, Miyoshi, Eiji, Hirai, Toshihiro, Nakajima, Kiyokazu, Nishitani, Akiko, Souma, Yoshihito, Sawa, Yoshiki, Nishida, Toshirou

“…Most adult gastrointestinal stromal tumors (GIST) are thought to be caused by activating mutations in the KIT or PDGFRA gene. However, many juvenile GIST lack…”
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The influence of excessive IL-6 production in vivo on the development and function of Foxp3+ regulatory T cells by Fujimoto, Minoru, Nakano, Mayumi, Terabe, Fumitaka, Kawahata, Hirohisa, Ohkawara, Tomoharu, Han, Yongmei, Ripley, Barry, Serada, Satoshi, Nishikawa, Teppei, Kimura, Akihiro, Nomura, Shintaro, Kishimoto, Tadamitsu, Naka, Tetsuji

“…IL-6 is a proinflammatory cytokine and its overproduction is implicated in a variety of inflammatory disorders. Recent in vitro analyses suggest that IL-6 is a…”
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iTRAQ-based proteomic identification of leucine-rich alpha-2 glycoprotein as a novel inflammatory biomarker in autoimmune diseases by Serada, Satoshi, Fujimoto, Minoru, Ogata, Atsushi, Terabe, Fumitaka, Hirano, Toru, Iijima, Hideki, Shinzaki, Shinichiro, Nishikawa, Teppei, Ohkawara, Tomoharu, Iwahori, Kota, Ohguro, Nobuyuki, Kishimoto, Tadamitsu, Naka, Tetsuji

“…To identify a novel serum biomarker of disease activity in inflammatory autoimmune disorders. Sera obtained from rheumatoid arthritis (RA) patients before and…”
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Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulatory T cells in experimental autoimmune uveoretinitis by Haruta, Hiroshi, Ohguro, Nobuyuki, Fujimoto, Minoru, Hohki, Satoshi, Terabe, Fumitaka, Serada, Satoshi, Nomura, Shintaro, Nishida, Kohji, Kishimoto, Tadamitsu, Naka, Tetsuji

“…PURPOSE. Both Th17 and Th1 cells contribute to experimental autoimmune uveoretinitis (EAU). Interleukin-6 (IL-6) blockade inhibits Th17 differentiation in EAU…”
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Su1092 Age of Onset Is Associated With Seasonality of Onset and Exacerbation in Inflammatory Bowel Disease: A Multi-Center Observational Study by the Osaka Gut Forum by Araki, Manabu, Shinzaki, Shinichiro, Lijima, Hideki, Hiyama, Satoshi, Yamada, Takuya, Arimitsu, Shoko, Komori, Masato, Ito, Mari, Mukai, Akira, Nakajima, Sachiko, Terabe, Fumitaka, Kinoshita, Kazuo, Kitamura, Shinji, Murayama, Yoko, Ogawa, Hiroyuki, Yasunaga, Yuichi, Oshita, Masahide, Masuda, Eiji, Tsujii, Masahiko, Takehara, Tetsuo

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Comparative analysis of the effects of anti‐IL‐6 receptor mAb and anti‐TNF mAb treatment on CD4+ T‐cell responses in murine colitis by Terabe, Fumitaka, Fujimoto, Minoru, Serada, Satoshi, Shinzaki, Shinichiro, Iijima, Hideki, Tsujii, Masahiko, Hayashi, Norio, Nomura, Shintaro, Kawahata, Hirohisa, Jang, Myoung Ho, Miyasaka, Masayuki, Mihara, Masahiko, Ohsugi, Yoshiyuki, Kishimoto, Tadamitsu, Naka, Tetsuji

“…Background: The efficacy of anti‐tumor necrosis factor monoclonal antibody (anti‐TNF mAb) for Crohn's disease (CD) is well established, and anti‐interleukin‐6…”
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PS1-28 The effect of IL-6 overproduction in vivo on wound healing by Fujimoto, Minoru, Kotobuki, Yorihisa, Kitaba, Shun, Ukita, Tomohiro, Terabe, Fumitaka, Haruta, Hiroshi, Kishimoto, Tadamitsu, Naka, Tetsuji

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PS1-21 Blockade of IL-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses by Hohki, Satoshi, Ohguro, Nobuyuki, Haruta, Hiroshi, Terabe, Fumitaka, Serada, Satoshi, Fujimoto, Minoru, Kishimoto, Tadamitsu, Naka, Tetsuji

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Identification of leucine rich alpha 2 glycoprotein as a novel biomarker associated with disease activity of inflammatory autoimmune disorders by Serada, Satoshi, Terabe, Fumitaka, Fujimoto, Minoru, Nishikawa, Teppei, Kishimoto, Tadamitsu, Naka, Tetsuji

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Etanercept improved primary biliary cirrhosis associated with rheumatoid arthritis by Ogata, Atsushi, Terabe, Fumitaka, Nakanishi, Kaori, Kawai, Mari, Kuwahara, Yusuke, Hirano, Toru, Arimitsu, Jyunsuke, Hagihara, Keisuke, Shima, Yoshihito, Narazaki, Masashi, Tanaka, Toshio, Kawase, Ichiro

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85 Anti-interleukin-6 receptor antibody prevents T-cell transfer colitis not only via suppression of Th17 differentiation but also via suppression of Th1 proliferation by Terabe, Fumitaka, Fujimoto, Minoru, Serada, Satoshi, Horino, Jirou, Takahashi, Tsuyoshi, Souma, Yoshihito, Matsukawa, Yuko, Nishikawa, Teppei, Ohkawara, Tomoharu, Ripley, Barry, Kishimoto, Tadamitsu, Naka, Tetsuji

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