Search Results - "Terán, Joel L"

Diastereoselective Functionalization of Chiral N‐Acyl‐1,3‐oxazolidines and Their Applications in the Synthesis of Bioactive Molecules by Morales‐Monarca, Gerardo H., Gnecco, Dino, Terán, Joel L.

“…1,3‐Oxazolidines, derived from widely available enantiomerically pure 1,2‐aminoalcohols, are versatile chiral auxiliaries for several key transformations,…”
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Correlation between Molecular Docking and the Stabilizing Interaction of HOMO-LUMO: Spirostans in CHK1 and CHK2, an In Silico Cancer Approach by Rosales-López, Antonio, López-Castillo, Guiee N, Sandoval-Ramírez, Jesús, Terán, Joel L, Carrasco-Carballo, Alan

“…Checkpoint kinases 1 and 2 (CHK1 and CHK2) are enzymes that are involved in the control of DNA damage. At the present time, these enzymes are some of the most…”
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β -Secretase-1: In Silico Drug Reposition for Alzheimer's Disease by Galeana-Ascencio, Roberto A, Mendieta, Liliana, Limon, Daniel I, Gnecco, Dino, Terán, Joel L, Orea, María L, Carrasco-Carballo, Alan

“…The -secretase-1 enzyme (BACE-1) performs a key role in the production of beta-Amyloid protein (Aβ), which is associated with the development of Alzheimer's…”
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Chiral Indolizinium Salts Derived from 2-Pyridinecarbaldehyde-First Diastereoselective Syntheses of (-)-1- epi- lentiginosine by Rodriguez-Matsui, Hisami, Aparicio, David M, Orea, María L, Juárez, Jorge R, Gómez-Calvario, Victor, Gnecco, Dino, Carrasco-Carballo, Alan, Terán, Joel L

“…The first diastereoselective synthesis of (-)-1- -lentiginosine from a common chiral -epoxyamide derived from 2-pyridincarbaldehyde is reported. This…”
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The Stabilizing Role of the Intramolecular C–H···O Hydrogen Bond in Cyclic Amides Derived From α‑Methylbenzylamine by Sandoval-Lira, Jacinto, Fuentes, Lilia, Quintero, Leticia, Höpfl, Herbert, Hernández-Pérez, Julio M, Terán, Joel L, Sartillo-Piscil, Fernando

“…A series of five-, six-, seven-, and eight-membered lactams containing the chiral auxiliary α-methylbenzylamine were structurally analyzed and further studied…”
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An approach for the diastereoselective synthesis of (R)‐(+)‐methyl pipecolate and (+)‐dextro‐erythrophacetoperane from (S)‐(−)‐methylbenzylamine by Aguilar‐Aguilar, Alan, Carrasco‐Carballo, Alan, Gnecco, Dino, Rodríguez‐Matsui, Hisami, Aparicio‐Solano, David, Terán, Joel L.

“…A diastereoselective synthesis for the preparation of (R)‐methyl pipecolate and dextro‐erythrophacetoperane, analogs of methylphenidate, drugs used to treat…”
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α-(Aminomethyl)acrylates as acceptors in radical–polar crossover 1,4-additions of dialkylzincs: insights into enolate formation and trapping by Palillero-Cisneros, Angel, Gordillo-Guerra, Paola G, García-Alvarez, Fernando, Jackowski, Olivier, Ferreira, Franck, Chemla, Fabrice, Terán, Joel L, Perez-Luna, Alejandro

“…We demonstrate that α-(aminomethyl)acrylates are suitable acceptors for 1,4-additions of dialkylzincs in aerobic conditions. The air-promoted radical–polar…”
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Diastereoselective synthesis of new zwitterionic bicyclic lactams, scaffolds for construction of 2-substituted-4-hydroxy piperidine and its pipecolic acid derivatives by Reyes-Bravo, Enrique, Gnecco, Dino, Juárez, Jorge R, Orea, María L, Bernès, Sylvain, Aparicio, David M, Terán, Joel L

“…The synthesis of new chiral highly functionalized zwitterionic bicyclic lactams starting from acyclic β-enaminoesters derived from ( R )-(−)-2-phenylglycinol…”
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L-Aspartic acid pyridinium salts: In silico, synthesis and adjuvant vs antibiotic antibacterial evaluation by Gutiérrez Cano, Jessica R., Paulina Morales-Sandoval, I., Gnecco, Dino, Carrasco-Carballo, Alan, Terán, Joel L.

“…[Display omitted] •L-Aspartic pyr salts can cross membranes and affect CATIII, DNA GyrB and TryRS.•L-Aspartic pyr salts are effective as antibiotics with MIC…”
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Divergent Synthesis of 5,6- and 3,6-Dihydropyridin-2(1H)-one via Intramolecular Knoevenagel Condensation by L. Terán, Joel, M. Aparicio, David, Bocardo-Bautista, Arturo, L. Orea, María, R. Juárez, Jorge, Gnecco, Dino

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A Concise Stereoselective Synthesis of (R)‐2‐Benzylmorpholine and ML398 from (R)‐(−)‐2‐Phenylglycinol by Torres, Saúl, Velasco, Manuel, Gallegos‐Rojas, José Ángel, Bernès, Sylvain, Orea, María L., Terán, Joel L., Huelgas, Gabriela, Gómez‐Calvario, Víctor, Juárez, Jorge R.

“…We describe here an efficient stereoselective method for the preparation of (R)‐2‐benzylmorpholine and ML398. The present method features a high…”
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Diastereoselective Synthesis of 3-Alkylindoloquinolizine Derivatives via Regiospecific Oxidative Cyclization by R. Juárez, Jorge, Morales-Barba, Susana, L. Terán, Joel, Gnecco, Dino, L. Orea, María, M. Aparicio, David, Gómez-Calvario, Víctor

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Preparation of Chiral β-Enamino Esters from Methyl Propiolate: Synthesis of Chiral Methyl 1-Substituted 6-Oxo-1,4,5,6-tetrahydropyridine-3-carboxylates by Gnecco, Dino, L. Orea, María, Pilotzi, Hugo, M. Aparicio, David, L. Terán, Joel, R. Juárez, Jorge

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Highly Regioselective Ring Opening of a Common N,N-Dialkylaziridinium Ion by Carboxylic Acids by R. Juárez, Jorge, Hernández, Ulises, Velasco, Manuel, Vázquez, Jaime, L. Terán, Joel, Gnecco, Dino, L. Orea, María, M. Aparicio, David

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Diastereoselective Approach to cis-4-Methyl/thiol-Pipecolic Esters Based on RCM Reaction and Conjugate Michael Addition by Zárate, Araceli, Orea, Laura, Juárez, Jorge R., Castro, Alejandro, Mendoza, Angel, Gnecco, Dino, Terán, Joel L.

“…A synthetic route for the access to enantiopure cis-4-methyl/thiol-pipecolic esters is presented. It is based on the ring-closing metathesis reaction to build…”
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Diastereoselective synthesis of aryl and alkyl trans-glycidic amides from pseudoephedrine-derived sulfonium salt. Chemospecific exo-tet ring closure for morpholin-3-ones by Aparicio, David M., Gnecco, Dino, Juárez, Jorge R., Orea, María L., Mendoza, Angel, Waksman, Noemí, Salazar, Ricardo, Fores-Alamo, Marcos, Terán, Joel L.

“…A regiospecific and high diastereoselective synthesis of trans-glycidic amides coming from a common pseudoephedrine sulfonium salt 2 precursor is presented…”
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Diastereoselective arylation of enantiopure 3-bromopiperidin-2-one derived from ( R)-(−)-2-phenylglycinol with organocuprate reagents by Romero, Oscar, Castro, Alejandro, Terán, Joel L., Gnecco, Dino, Orea, María L., Mendoza, Ángel, Flores, Marcos, Roa, Luis F., Juárez, Jorge R.

“…The diastereoselective substitution of 3-bromolactam derived from ( R)-(−)-2-phenylglycinol with a variety of arylcuprate reagents is presented. The…”
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Application of amide-stabilized sulfur ylide reactivity to the stereodivergent synthesis of ( R, S)- and ( S, R)-reboxetine by Aparicio, David M., Terán, Joel L., Gnecco, Dino, Galindo, Alberto, Juárez, Jorge R., Orea, María L., Mendoza, Angel

“…A simple access to ( R, S)- and ( S, R)-reboxetine from a single chiral sulfonium salt 4 is reported. This approach, based on a stabilized sulfur…”
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Boron trifluoride etherate for regioselective rearrangement or opening of secondary aryl glycidic amides by Aparicio, David M., Tépox-Luna, Dulce, Bedolla-Medrano, Mercedes, Gnecco, Dino, Juárez, Jorge R., Mendoza, Ángel, Orea, María L., Terán, Joel L.

“…A regioselective 1,2-acyl, 1,2-hydrogen migration, and intermolecular opening of secondary aryl glycidic amides catalyzed by BF3·OEt2 were investigated…”
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Crystal structures of two chiral piperidine derivatives: 1-[(1 R )-2-hydroxy-1-phenylethyl]piperidin-4-one and 8-[(1 S )-1-phenylethyl]-1,4-dioxa-8-azaspiro[4.5]decane-7-thione by Romero, Nancy, Bernès, Sylvain, Roa, Luis F., Terán, Joel L., Gnecco, Dino

“…The crystal structures of the two title piperidine derivatives show different conformations for the six-membered heterocycle. The N -substituted 4-piperidinone…”
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