Search Results - "Tepper, Armand W.J.W."

Shape and Release Control of a Peptide Decorated Vesicle through pH Sensitive Orthogonal Supramolecular Interactions by Versluis, Frank, Tomatsu, Itsuro, Kehr, Seda, Fregonese, Carlo, Tepper, Armand W.J.W, Stuart, Marc C. A, Ravoo, Bart Jan, Koning, Roman I, Kros, Alexander

“…A pH sensitive carrier is obtained by coating a cyclodextrin vesicle with an adamantane-terminated octapeptide through the formation of an inclusion complex…”
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Identification of a Radical Intermediate in the Enzymatic Reduction of Oxygen by a Small Laccase by Tepper, Armand W.J.W, Milikisyants, Sergey, Sottini, Silvia, Vijgenboom, Erik, Groenen, Edgar J.J, Canters, Gerard W

“…The enzyme mechanism of the Cu-containing small laccase (SLAC) from Streptomyces coelicolor has been investigated by optical and electron paramagnetic…”
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NOVEL AB OLIGOMER–SPECIFIC ANTIBODIES AND STABILIZED AB OLIGOMERS AS RELIABLE AND DISEASE RELEVANT REFERENCE STANDARDS IN ALZHEIMER’S BIOMARKER ASSAYS by Tepper, Armand W.J.W, van Diggelen, Femke, de Poli, Angela, Scheefhals, Guus A.P.H, Vis, Joost D.J, Hoogveld, Emily, Schut, Ivar C, Anderegg, Birgit, de Boer, Marco

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Bi-Enzyme Sensor for Phenolic Compounds with Fluorescent Read-Out by Strianese, Maria, Zauner, Gerhild, Tabares, Leandro C, Tepper, Armand W. J. W., De Martino, Franco, Pellecchia, Claudio, Aartsma, Thijs J., Canters, Gerard W.

“…In this paper, the use of tyrosinase (Ty) from Streptomyces antibioticus, labeled with a fluorescent tag, in combination with soluble quinoprotein…”
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Aβ oligomers as tractable drug targets in Alzheimer's disease: in vivo proof of concept for the oligomer-binding small-molecule therapeutic candidate cbb68 by Tepper, Armand W.J.W, de Boer, Elizabeth C, Hoogveld, Emily, Vis, Joost D.J, Schut, Ivar C, Vereyken, Ingrid J, Hoffmann, Marcel, Scheefhals, Guus A.P.H

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Determination of phenolic compounds using recombinant tyrosinase from Streptomyces antibioticus by Streffer, Katrin, Vijgenboom, Erik, Tepper, Armand W.J.W, Makower, Alexander, Scheller, Frieder W, Canters, Gerard W, Wollenberger, Ulla

“…Properties of Streptomyces antibioticus tyrosinase and the implementation of the enzyme in a biosensor for the detection of phenolic compounds were…”
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Structural Basis and Mechanism of the Inhibition of the Type-3 Copper Protein Tyrosinase from Streptomyces antibioticusby Halide Ions by Tepper, Armand W.J.W., Bubacco, Luigi, Canters, Gerard W.

“…The inhibition of the type-3 copper enzyme tyrosinase by halide ions was studied by kinetic and paramagnetic 1 H NMR methods. All halides are inhibitors in the…”
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What are the structural features of the active site that define binuclear copper proteins function? by Bubacco, Luigi, van Gastel, Maurice, Benfatto, Maurizio, Tepper, Armand W.J.W, Canters, Gerard W

“…The structural basis that define the physiological functions of binuclear copper enzymes is discussed in the frame of the data generated by a broad…”
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The interactome of stabilized α‐synuclein oligomers and neuronal proteins by Diggelen, Femke, Frank, Signe Andrea, Somavarapu, Arun Kumar, Scavenius, Carsten, Apetri, Mihaela M., Nielsen, Janni, Tepper, Armand W. J. W., Enghild, Jan J., Otzen, Daniel E.

“…While it is generally accepted that α‐synuclein oligomers (αSOs) play an important role in neurodegeneration in Parkinson's disease, the basis for their…”
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Development and characterization of rabbit monoclonal antibodies that recognize human spermine oxidase and application to immunohistochemistry of human cancer tissues by Tepper, Armand W J W, Chu, Gerald, Klaren, Vincent N A, Kalin, Jay H, Molina-Ortiz, Patricia, Impagliazzo, Antonietta

“…The enzyme spermine oxidase (SMOX) is involved in polyamine catabolism and converts spermine to spermidine. The enzymatic reaction generates reactive hydrogen…”
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α‐Synuclein Oligomers: A Study in Diversity by van Diggelen, Femke, Tepper, Armand W. J. W., Apetri, Mihaela M., Otzen, Daniel E.

“…A critical step in Parkinson's disease (PD) is the formation of toxic α‐synuclein oligomers (αSOs). In vitro αSOs are formed by self‐assembly of α‐synuclein at…”
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CROSSBETA STABLE Aβ OLIGOMERS: DISEASE-RELEVANT DRUG TARGETS AND VERSATILE REFERENCE STANDARDS IN BIOMARKER ASSAYS IN AD by Apetri, Mihaela, Tepper, Armand W.J.W., Hoogveld, Emily, Vis, Joost D.J., de Boer, Marco, Scheefhals, Guus A.P.H.

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Electrical Contacting of an Assembly of Pseudoazurin and Nitrite Reductase Using DNA-Directed Immobilization by Tepper, Armand W. J. W

“…A method for the electrical contacting of redox enzymes that obtain oxidizing or reducing equivalents from small electron-transfer proteins is demonstrated…”
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P4‐164: Aβ oligomers as tractable drug targets in Alzheimer's disease: in vivo proof of concept for the oligomer‐binding small‐molecule therapeutic candidate cbb68 by Tepper, Armand W.J.W., Boer, Elizabeth C., Hoogveld, Emily, Vis, Joost D.J., Schut, Ivar C., Vereyken, Ingrid J., Hoffmann, Marcel, Scheefhals, Guus A.P.H.

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P2‐161: Novel AB Oligomer–Specific Antibodies and Stabilized AB Oligomers as Reliable and Disease Relevant Reference Standards in Alzheimer’s Biomarker Assays by Tepper, Armand W.J.W., Diggelen, Femke, Poli, Angela, Scheefhals, Guus A.P.H., Vis, Joost D.J., Hoogveld, Emily, Schut, Ivar C., Anderegg, Birgit, Boer, Marco

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Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor by Diaz, Elsie, Adhikary, Suraj, Tepper, Armand W. J. W., Riley, Daniel, Ortiz-Meoz, Rodrigo, Krosky, Daniel, Buyck, Christophe, Lamenca, Carolina Martinez, Llaveria, Josep, Fang, Lichao, Kalin, Jay H., Klaren, Vincent N. A., Fahmy, Shorouk, Shaffer, Paul L., Kirkpatrick, Robert, Carbajo, Rodrigo J., Thomsen, Maren, Impagliazzo, Antonietta

“…Human spermine oxidase (hSMOX) plays a central role in polyamine catabolism. Due to its association with several pathological processes, including inflammation…”
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Sensitive detection of histamine using fluorescently labeled oxido-reductases by Gustiananda, Marsia, Andreoni, Alessio, Tabares, Leandro C., Tepper, Armand W.J.W., Fortunato, Luca, Aartsma, Thijs J., Canters, Gerard W.

“…► A new FRET-based method for histamine detection in biological samples is presented. ► Usage of fluorescence allows for high sensitivity and precision. ►…”
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Site−Site Interactions Enhances Intramolecular Electron Transfer in Streptomyces coelicolor laccase by Farver, Ole, Tepper, Armand W. J. W, Wherland, Scot, Canters, Gerard W, Pecht, Israel

“…Control of electron transfer rates, caused by intrinsic protein structural properties, is an intriguing feature of internal biological electron transfer (ET)…”
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A protein-based oxygen biosensor for high-throughput monitoring of cell growth and cell viability by Strianese, Maria, Zauner, Gerhild, Tepper, Armand W.J.W., Bubacco, Luigi, Breukink, Eefjan, Aartsma, Thijs J., Canters, Gerard W., Tabares, Leandro C.

“…Fluorescently labeled hemocyanin has been previously proposed as an oxygen sensor. In this study, we explored the efficacy of this biosensor for monitoring the…”
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Involvement of Tyr108 in the Enzyme Mechanism of the Small Laccase from Streptomyces coelicolor by Gupta, Ankur, Nederlof, Igor, Sottini, Silvia, Tepper, Armand W. J. W, Groenen, Edgar J. J, Thomassen, Ellen A. J, Canters, Gerard W

“…The enzyme mechanism of the multicopper oxidase (MCO) SLAC from Streptomyces coelicolor was investigated by structural (XRD), spectroscopic (optical, EPR), and…”
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